Listar Artículos (Fisiología Médica y Biofísica) por título
Mostrando ítems 267-286 de 330
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Artículo
Single K+ channels in membrane patches of arterial chemoreceptor cells are modulated by 02 tension
(1991)Type I cells of the carotid body are known to participate in the detection of 02 tension in arterial blood but the primary ...
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Ponencia
Single restraint stress sensitizes acute chewing movements induced by haloperidol, but not if the 5-HT agonist 8-OH-DPAT is given prior to stress
(Elsevier, 1997)The objective of this study was two-fold: ( i) to analyze behavioral sensitization to haloperidol 2 weeks after single ...
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El sistema endógeno de serotonina no participa en la abstinencia opiácea, aunque su inhibición por estimulación del receptor 5-HT1A incrementa la eficacia antidisfórica de la clonidina en ratas
(2003)El objetivo del estudio fue discernir el papel del sistema endógeno de serotonina en la abstinencia opiácea, tanto en su ...
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Artículo
SMN Is Physiologically Downregulated at Wild-Type Motor Nerve Terminals but Aggregates Together with Neurofilaments in SMA Mouse Models
(MDPI, 2022-10-20)muscular atrophy (SMA). SMN forms the core of a protein complex localized at the cytoplasm and nuclear gems and that ...
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Artículo
SMN Requirement for Synaptic Vesicle, Active Zone and Microtubule Postnatal Organization in Motor Nerve Terminals
(2011-10-12)Low levels of the Survival Motor Neuron (SMN) protein produce Spinal Muscular Atrophy (SMA), a severe monogenetic disease ...
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Artículo
Smn-Deficiency Increases the Intrinsic Excitability of Motoneurons
(2017-09-05)During development, motoneurons experience significant changes in their size and in the number and strength of connections ...
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Sodium and Calcium Currents in Dispersed Mammalian Septal Neurons
(1991)Voltage-gated Na+ and Ca2+ conductances of freshly dissociated septal neurons were studied in the whole-cell configuration ...
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Artículo
SOS GEFs in health and disease
(Elsevier, 2020)SOS1 and SOS2 are the most universal and widely expressed family of guanine exchange factors (GEFs) capable or activating ...
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Artículo
SOS2 Comes to the Fore: Differential Functionalities in Physiology and Pathology
(MDPI, 2021-06-21)The SOS family of Ras-GEFs encompasses two highly homologous and widely expressed members, SOS1 and SOS2. Despite their ...
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Artículo
Spanish Cell Therapy Network (TerCel): 15 years of successful collaborative translational research
(Elsevier, 2020)In the current article we summarize the 15-year experience of the Spanish Cell Therapy Network (TerCel), a successful ...
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Artículo
Spike protein of SARS-CoV-2 Omicron variant An in-silico study evaluating spike interactions and immune evasion
(Frontiers Media, 2022-11-29)Background: The fundamentals of the infectivity and immune evasion of the SARS-CoV-2 Omicron variant are not yet fully ...
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Artículo
SPT6-driven error-free DNA repair safeguards genomic stability of glioblastoma cancer stem-like cells
(Nature Portfolio, 2020)Glioblastoma cancer-stem like cells (GSCs) display marked resistance to ionizing radiation (IR), a standard of care for ...
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Artículo
State-Dependent Subnetworks of Parvalbumin-Expressing Interneurons in Neocortex
(Cell Press, 2019-02-26)Brain state determines patterns of spiking output that underlie behavior. In neocortex, brain state is reflected in the ...
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Artículo
Statistical Agnostic Mapping: A framework in neuroimaging based on concentration inequalities
(Elsevier, 2021-02)In the 1970s a novel branch of statistics emerged focusing its effort on the selection of a function for the pattern ...
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Artículo
STIM and Orai1 Variants in Store-Operated Calcium Entry
(Frontiers Research Foundation, 2016-01-13)Store-operated Ca2+ entry (SOCE) is an ubiquitous mechanism for Ca2+ entry in eukaryotic cells. This route for Ca2+ influx ...
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Artículo
Store-operated calcium entry in breast cancer cells is insensitive to Orai1 and STIM1 N-linked glycosylation
(MDPI, 2022-12-29)N-linked glycosylation is a post-translational modification that affects protein function, structure, and interaction ...
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Structure/Function Analysis of Ca2 + Binding to the C2A Domain of Synaptotagmin 1
(2002)Synaptotagmin 1, a Ca2+ sensor for fast synaptic vesicle exocytosis, contains two C2 domains that form Ca2+ -dependent ...
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Artículo
Succinate dehydrogenase/complex II is critical for metabolic and epigenetic regulation of T cell proliferation and inflammation
(American Association for the Advancement of Science, 2022)Effective T cell-mediated immune responses require the proper allocation of metabolic resources to sustain growth, ...
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Artículo
Sushi domain-containing protein 4 controls synaptic plasticity and motor learning
(2021)Fine control of protein stoichiometry at synapses underlies brain function and plasticity. How proteostasis is controlled ...
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Artículo
Synapse Formation and Function Across Species: Ancient Roles for CCP, CUB, and TSP-1 Structural Domains
(Frontiers Media S.A., 2022)The appearance of synapses was a crucial step in the creation of the variety of nervous systems that are found in the ...