Fisiología Médica y Biofísica
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Article
IGF-1 regulates astrocytic phagocytosis and inflammation through the p110α isoform of PI3K in a sex-specific manner
(Willey, 2022)Insulin-like growth factor-I (IGF-I) signaling plays a key role in neuroinflammation. Here we show that IGF-1 also regulates ...
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Article
The carotid body, a neurogenic niche in the adult peripheral nervous system
(Univ pisa, 2010)We have described a new population of adult neural stem cells residing in the carotid body, a chemoreceptor organ in the ...
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Chapter of Book
A pathophysiological view of the neural stem cell niche
(Nova Science Publishers, INC. U.S., 2011)Neural stem cells were described in the nervous system some decades ago as being responsible for adult neurogenesis and ...
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Article
Genetic divergence and demography of pudu deer (Pudu puda) in five provinces of southern Chile, analyzed through latitudinal and longitudinal ranges
(Pensoft Publishers, 2022)Pudu deer (Pudu puda) is endemic to the temperate rainforests of Chile. Genetic studies at different geographic scales for ...
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PhD Thesis
Tratamiento antitrombótico de la estenosis carotídea en concomitancia con fibrilación auricular y en ictus isquémico agudo
(2024-01-30)La estenosis carotídea de etiología aterosclerótica es una de las causas más frecuentes de ictus en la población mundial. ...
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Article
Selective accumulation of biotin in arterial chemoreceptors: requirement for carotid body exocytotic dopamine secretion
(2016-12)Biotin is a water-soluble vitamin required for the function of carboxylases as well asfor the regulation of gene expression. ...
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PhD Thesis
Determinación de CTCs como marcador pronóstico en el cáncer de páncreas
(2023-12-11)Introducción. El cáncer de páncreas es un tumor maligno intratable en el que la mayoría de los pacientes no muestran ...
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PhD Thesis
Impacto clínico de la implantación del Centro Andaluz de Teleictus (CATI) en la atención del ictus en Andalucía
(2023-12-18)Introducción: El ictus es una enfermedad tiempo dependiente que supone un problema de salud grave, con gran impacto ...
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Article
Gene expression analyses reveal metabolic specifications in acute O-2-sensing chemoreceptor cells
(Wiley, 2017-09)Acute O2sensing is a fundamental property of cells in the peripheral chemoreceptors,e.g. glomus cells in the carotid body ...
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PhD Thesis
Remodelado cardiaco inverso: predictores e impacto pronóstico durante el seguimiento de pacientes con alto riesgo de descompensación en una unidad de insuficiencia cardiaca
(2023-11-13)INTRODUCCIÓN: La insuficiencia cardiaca (IC) es una de las enfermedades cardiovasculares con mayor invalidez, mortalidad ...
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Article
Expression Pattern of Aquaporin 1 and Aquaporin 3 in Melanocytic and Nonmelanocytic Skin Tumors
(American journal of clinical pathology, 2019)Objectives: Study of aquaporin 1 (AQP1) and aquaporin 3 (AQP3) expression to understand its potential role in the ...
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Article
Long-term immunosuppression for CNS mouse xenotransplantation: Effects on nigrostriatal neurodegeneration and neuroprotective carotid body cell therapy
(Wiley, 2018)Abstract Background: The use of long-term immunosuppressive treatments on neural trans plantation has been controversial ...
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Article
Clinical Viability of Boron Neutron Capture Therapy for Personalized Radiation Treatment
(MDPI, 2022)bstract: Boron Neutron Capture Therapy (BNCT) is a promising binary disease-targeted therapy, as neutrons preferentially ...
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Article
Overexpression of AQP3 Modifies the Cell Cycle and the Proliferation Rate of Mammalian Cells in Culture
(PUBLIC LIBRARY SCIENCE, 2015-09-14)Abnormal AQP3 overexpression in tumor cells of different origins has been reported and a role for this enhanced AQP3 ...
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Article
Generation of Periventricular Reactive Astrocytes Overexpressing Aquaporin 4 Is Stimulated by Mesenchymal Stem Cell Therapy
(MDPI AG, 2023-03-15)Aquaporin-4 (AQP4) plays a crucial role in brain water circulation and is considered a therapeutic target in hydrocephalus. ...
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Article
Development of cytosolic hypoxia and hypoxia-inducible factor stabilization are facilitated by aquaporin-1 expression
(Elsevier, 2007)O2 is essential for aerobic life, and the classic view is that it diffuses freely across the plasma membrane. However, ...
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Article
MCTP system model based on linear programming optimization of apertures obtained from sequencing patient image data maps
(Wiley, 2014)Purpose: We present a hybrid direct MLC aperture optimization model exclusively based on sequencing of patient imaging ...
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Article
Dose painting by means of Monte Carlo treatment planning at the voxel level
(Elsevier, 2017)Purpose To develop a new optimization algorithm to carry out true dose painting by numbers (DPBN) planning based on full ...
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Article
Clinical implementation of combined modulated electron and photon beams with conventional MLC for accelerated partial breast irradiation
(Elsevier, 2017-07)Purpose: To report the clinical implementation of a novel external beam radiotherapy technique for accelerated partial ...
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Article
Sexually divergent development of depression-related brain networks during healthy human adolescence.
(American Association for the Advancement of Science, 2022)Sexual differences in human brain development could be relevant to sex differences in the incidence of depres- sion during ...