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Artículo
Cellular distribution of brain aquaporins and their contribution to cerebrospinal fluid homeostasis and hydrocephalus
(MDPI, 2022)
Brain aquaporins facilitate the movement of water between the four water compartments: blood, cerebrospinal fluid, interstitial fluid, and intracellular fluid. This work analyzes the expression of the four most abundant ...
Artículo
Targeting Aquaporin Function: Potent Inhibition of Aquaglyceroporin-3 by a Gold-Based Compound
(Public Library of Science, 2012-05-18)
Aquaporins (AQPs) are membrane channels that conduct water and small solutes such as glycerol and are involved in many physiological functions. Aquaporin-based modulator drugs are predicted to be of broad potential utility ...
Artículo
AQP1 and AQP4 Contribution to Cerebrospinal Fluid Homeostasis
(MDPI, 2019-02-24)
Aquaporin 1 (AQP1), expressed in epithelial cells of the choroid plexus, and aquaporin 4 (AQP4) present in ependymal cells and glia limitants have been proposed to play a significant role in cerebrospinal fluid (CSF) ...
Artículo
Aquaporin-4 expression switches from white to gray matter regions during postnatal development of the central nervous system
(MDPI, 2023-02-03)
Aquaporin-4 (AQP4) is the most abundant water channel in the central nervous system and plays a fundamental role in maintaining water homeostasis there. In adult mice, AQP4 is located mainly in ependymal cells, in the ...