Buscar
Mostrando ítems 1-6 de 6
Artículo
Cellular distribution of brain aquaporins and their contribution to cerebrospinal fluid homeostasis and hydrocephalus
(MDPI, 2022)
Brain aquaporins facilitate the movement of water between the four water compartments: blood, cerebrospinal fluid, interstitial fluid, and intracellular fluid. This work analyzes the expression of the four most abundant ...
Artículo
Aquaporin-4 Mediates Permanent Brain Alterations in a Mouse Model of Hypoxia-Aged Hydrocephalus
(MDPI, 2021-09-09)
Aquaporin-4 (AQP4) is the principal water channel in the brain being expressed in astrocytes and ependymal cells. AQP4 plays an important role in cerebrospinal fluid (CSF) homeostasis, and alterations in its expression ...
Artículo
Evaluation of aquaporins in the cerebrospinal fluid in patients with idiopathic normal pressure hydrocephalus
(PLOS, 2021)
Brain aquaporin 1 (AQP1) and AQP4 are involved in cerebrospinal fluid (CSF) homeostasis and might participate in the origin of hydrocephalus. Studies have shown alterations of perivascular AQP4 expression in idiopathic ...
Tesis Doctoral
Contribución de las acuaporinas cerebrales a la homeostasis del líquido cefalorraquídeo y su papel en el desarrollo de la hidrocefalia asociada a hipoxia y envejecimiento
(2020-10-07)
Las acuaporinas son una familia de pequeñas proteínas integrales de membrana (≈ 30 kDa) que se expresan ampliamente en el cuerpo. Tradicionalmente se las han definido como facilitadores del transporte pasivo de agua a ...
Artículo
Generation of Periventricular Reactive Astrocytes Overexpressing Aquaporin 4 Is Stimulated by Mesenchymal Stem Cell Therapy
(MDPI AG, 2023-03-15)
Aquaporin-4 (AQP4) plays a crucial role in brain water circulation and is considered a therapeutic target in hydrocephalus. Congenital hydrocephalus is associated with a reaction of astrocytes in the periventricular white ...
Artículo
Aquaporin-4 expression switches from white to gray matter regions during postnatal development of the central nervous system
(MDPI, 2023-02-03)
Aquaporin-4 (AQP4) is the most abundant water channel in the central nervous system and plays a fundamental role in maintaining water homeostasis there. In adult mice, AQP4 is located mainly in ependymal cells, in the ...