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Now showing items 1-10 of 19
Article
Physical exercise and myokines
(Spanish Society of Anti-Aging Medicine and Longevity, 2019-10)
Among the types of muscles present in the body is skeletal muscle, which is the one that allows the development of physical activity thanks to the contractile activity of its muscle cells. It is known that physical ...
Article
Folic acid supplementation: some practical aspects
(Federation of Anti-Aging Medicine Societies, 2012)
Since 1956, when Harman first postulated the free radical theory of aging, numerous studies have been carried out to test the protective action of antioxidants. One of these protective compounds used in antioxidant therapy ...
Article
Treatment with mesenchymal stem cells in an animal model of parkinson´s disease
(Federation of Anti-Aging Medicine Societies, 2015)
PhD Thesis
Estudio de la viabilidad y diferenciación de las células madre mesenquimales de tejido adiposo en condiciones de estrés oxidativo y envejecimiento. Posibilidad de su uso terapéutico e influencia del factor de elongación 2
(2016-01-22)
The present thesis is a compilation of several experiments about the use of adiposederived mesenchymal stem cells (ADSCs) in cell therapy. The study focus on the behavior, molecular mechanisms and environment changes of ...
Article
Elongation factor 2-diphthamide is critical for translation of two IRES-dependent protein targets, XIAP and FGF2, under oxidative stress conditions
(Elsevier, 2013)
Elongation factor-2 (eEF2) catalyzes the movement of the ribosome along the mRNA. A single histidine residue in eEF2 (H715) is modified to form diphthamide. A role for eEF2 in cellular stress responses is highlighted by ...
Article
A Double-Blind, RCT Testing Beneficial Modulation of BDNF in Middle-Aged, Life Style-Stressed Subjects: A Clue to Brain Protection?
(JCDR, 2014)
Introduction: The aim of this prospective study was to see whether LD-1227, a quality-controlled marine nutraceuticals shown to protect experimental stress-induced hyppocampal degeneration, could beneficially modulate ...
Article
In vitro and in Vivo Protection by Melatonin Against the Decline of Elongation Factor-2 Caused by Lipid Peroxidation: Preservation of Protein Synthesis
(Wiley-Blackwell, 2012)
As organisms age, a considerable decrease in protein synthesis takes place in all tissues. Among the possible causes of the decline of translation in old animals are the modifications of elongation factor-2 (eEF- 2). eEF-2 ...
Article
Lipid peroxidation: Production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal
(Hindawi Publishing Corporation, 2014)
Lipid peroxidation can be described generally as a process under which oxidants such as free radicals attack lipids containing carbon-carbon double bond(s), especially polyunsaturated fatty acids (PUFAs). Over the last ...
Chapter of Book
Article
Effect of VBC-1814/7J, a poly-phytocompound, on a non-infectious model of pharyngitis
(Spandidos Publications, 2017)
Pharyngitis presents as an inflammation of the oropharynx, and clinical examination often shows evidence of nasopharyngitis. In numerous cases the condition occurs as a self-limiting illness of non-infectious aetiology, ...