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Now showing items 1-10 of 17
Article
Folic acid supplementation: some practical aspects
(Federation of Anti-Aging Medicine Societies, 2012)
Since 1956, when Harman first postulated the free radical theory of aging, numerous studies have been carried out to test the protective action of antioxidants. One of these protective compounds used in antioxidant therapy ...
Article
Treatment with mesenchymal stem cells in an animal model of parkinson´s disease
(Federation of Anti-Aging Medicine Societies, 2015)
PhD Thesis
Estudio de la viabilidad y diferenciación de las células madre mesenquimales de tejido adiposo en condiciones de estrés oxidativo y envejecimiento. Posibilidad de su uso terapéutico e influencia del factor de elongación 2
(2016-01-22)
The present thesis is a compilation of several experiments about the use of adiposederived mesenchymal stem cells (ADSCs) in cell therapy. The study focus on the behavior, molecular mechanisms and environment changes of ...
Article
The Emerging Role of Senotherapy in Cancer: A Comprehensive Review
(MDPI, 2023-07-22)
Senotherapy, a promising therapeutic strategy, has drawn a lot attention recently due to its potential for combating cancer. Senotherapy refers to the targeting of senescent cells to restore tissue homeostasis and mitigate ...
Article
Effect of Age and Lipoperoxidation in Rat and Human Adipose Tissue-Derived Stem Cells
(Hindawi, 2020)
A wide range of clinical applications in regenerative medicine were opened decades ago with the discovery of adult stem cells. Highly promising adult stem cells are mesenchymal stem/stromal cells derived from adipose tissue ...
Article
In vitro and in Vivo Protection by Melatonin Against the Decline of Elongation Factor-2 Caused by Lipid Peroxidation: Preservation of Protein Synthesis
(Wiley-Blackwell, 2012)
As organisms age, a considerable decrease in protein synthesis takes place in all tissues. Among the possible causes of the decline of translation in old animals are the modifications of elongation factor-2 (eEF- 2). eEF-2 ...
Article
Lipid peroxidation: Production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal
(Hindawi Publishing Corporation, 2014)
Lipid peroxidation can be described generally as a process under which oxidants such as free radicals attack lipids containing carbon-carbon double bond(s), especially polyunsaturated fatty acids (PUFAs). Over the last ...
Chapter of Book
Article
Immunolocalization of Substance P and NK-1 Receptor in ADIPOSE Stem Cells
(Wiley-Blackwell, 2017)
Substance P (SP) is a neuropeptide belonging to the thachykinin peptide family. SP, after binding to its receptor, the neurokinin 1 receptor (NK1R), controls several transcription factors such as NF-κB, hypoxia inducible ...
Article
Potential use of adipose tissue stem cells in the control of aging
(Federation of Anti-Aging Medicine Societies, 2012)
Cell therapy with adult stem cells is a new battle front for the control of aging. Before being used for this purpose, we need to answer several basic questions about the biochemistry and physiology of these cells. This ...