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Physical exercise and myokines
(Spanish Society of Anti-Aging Medicine and Longevity, 2019-10)
Among the types of muscles present in the body is skeletal muscle, which is the one that allows the development of physical activity thanks to the contractile activity of its muscle cells. It is known that physical ...
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Folic acid supplementation: some practical aspects
(Federation of Anti-Aging Medicine Societies, 2012)
Since 1956, when Harman first postulated the free radical theory of aging, numerous studies have been carried out to test the protective action of antioxidants. One of these protective compounds used in antioxidant therapy ...
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Treatment with mesenchymal stem cells in an animal model of parkinson´s disease
(Federation of Anti-Aging Medicine Societies, 2015)
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Effect of Age and Lipoperoxidation in Rat and Human Adipose Tissue-Derived Stem Cells
(Hindawi, 2020)
A wide range of clinical applications in regenerative medicine were opened decades ago with the discovery of adult stem cells. Highly promising adult stem cells are mesenchymal stem/stromal cells derived from adipose tissue ...
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In vitro and in Vivo Protection by Melatonin Against the Decline of Elongation Factor-2 Caused by Lipid Peroxidation: Preservation of Protein Synthesis
(Wiley-Blackwell, 2012)
As organisms age, a considerable decrease in protein synthesis takes place in all tissues. Among the possible causes of the decline of translation in old animals are the modifications of elongation factor-2 (eEF- 2). eEF-2 ...
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Potential use of adipose tissue stem cells in the control of aging
(Federation of Anti-Aging Medicine Societies, 2012)
Cell therapy with adult stem cells is a new battle front for the control of aging. Before being used for this purpose, we need to answer several basic questions about the biochemistry and physiology of these cells. This ...
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Dysregulation of the Hippo Pathway Signaling in Aging and Cancer
(Elsevier, 2019)
Human beings are facing emerging degenerative and cancer diseases, in large part, as a consequence of increased life expectancy. In the near future, researchers will have to put even more effort into fighting these new ...
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Aging and Oxidative Stress Decrease Pineal Elongation Factor 2: In Vivo Protective Effect of Melatonin in Young Rats Treated With Cumene Hydroperoxide
(Wiley-Blackwell, 2017)
We studied the alterations of Elongation Factor 2 (eEF2) in the pineal gland of aged rats as well as the possible protective role of exogenous melatonin on these changes in young rats treated with cumene hydroperoxide (CH), ...
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Advantages and Disadvantages of Apoptosis in the Aging Process
(Wiley-Blackwell, 2019)
Researchers cannot predict as yet how long a human being can live. Life expectancy has been steadily increasing in the last century, but perhaps not always the quality of life in parallel with it. Future generations will ...