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Browsing Artículos (Instituto de Investigaciones Químicas (IIQ) – CIC Cartuja) by Author "Díaz Quintana, Antonio Jesús"
Now showing items 1-20 of 25
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Article
A putative RNA binding protein from Plasmodium vivax apicoplast
García Mauriño, Sofía M.; Díaz Quintana, Antonio Jesús; Rivero Rodríguez, Francisco; Cruz Gallardo, Isabel; Grüttner, Christian; Hernández Vellisca, Marian; Díaz Moreno, Irene (Wiley, 2018)Malaria is caused by Apicomplexa protozoans from the Plasmodium genus entering the bloodstream of humans and animals through ...
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Article
ARL15 modulates magnesium homeostasis through N-glycosylation of CNNMs
Zolotarov, Yevgen; Ma, Chao; González Recio, Irene; Díaz Moreno, Irene; Díaz Quintana, Antonio Jesús; Martínez Cruz, Luis Alfonso (Springer, 2021)Cyclin M (CNNM1-4) proteins maintain cellular and body magnesium (Mg2+) homeostasis. Using various biochemical approaches, ...
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Article
Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition
Elena-Real, Carlos A.; Díaz Quintana, Antonio Jesús; González Arzola, Katiuska; Velázquez Campoy, Adrián; Orzáez, Mar; López Rivas, Abelardo; Gil Caballero, Sergio; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Nature Publishing Group, 2018)Apoptosis is a highly regulated form of programmed cell death, essential to the development and homeostasis of multicellular ...
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Article
Cytochrome c: Surfing Off of the Mitochondrial Membrane on the Tops of Complexes III and IV
Pérez Mejías, Gonzalo; Guerra Castellano, Alejandra; Díaz Quintana, Antonio Jesús; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Elsevier, 2019)The proper arrangement of protein components within the respiratory electron transport chain is nowadays a matter of intense ...
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Article
Exploring protein phosphorylation by combining computational approaches and biochemical methods
Pérez Mejías, Gonzalo; Velázquez Cruz, Alejandro; Guerra Castellano, Alejandra; Baños Jaime, Blanca; Díaz Quintana, Antonio Jesús; González Arzola, Katiuska; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Elsevier, 2020)Post-translational modifications of proteins expand their functional diversity, regulating the response of cells to a ...
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Article
Fluorinated chaperone-ß-cyclodextrin formulations for ß-glucocerebrosidase activity enhancement in neuronopathic Gaucher disease
García Moreno, M. Isabel; Mata, Mario de la; Sánchez Fernández, Elena Matilde; Benito, Juan M.; Díaz Quintana, Antonio Jesús; Fustero, Santos; Nanba, Eiji; Higaki, Katsumi; Sánchez-Alcazar, José Antonio; García Fernández, José Manuel; Ortiz Mellet, Carmen (American Chemical Society, 2017)Amphiphilic glycomimetics encompassing a rigid, undistortable nor-tropane skeleton based on 1,6-anhydro-L-idonojirimycin ...
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Article
Histone chaperone activity of Arabidopsis thaliana NRP1 is blocked by cytochrome c
González Arzola, Katiuska; Díaz Quintana, Antonio Jesús; Rivero Rodríguez, Francisco; Velázquez Campoy, Adrián; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Oxford University Press, 2017)Higher-order plants and mammals use similar mechanisms to repair and tolerate oxidative DNA damage. Most studies on the ...
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Article
Inhibition of the PP2A activity by the histone chaperone ANP32B is long-range allosterically regulated by respiratory cytochrome c
Rivero Rodríguez, Francisco; Díaz Quintana, Antonio Jesús; Velázquez Cruz, Alejandro; González Arzola, Katiuska; Gavilán Dorronzoro, María de la Paz; Velázquez Campoy, Adrián; Ríos Sánchez, Rosa María; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Elsevier, 2021)Repair of injured DNA relies on nucleosome dismantling by histone chaperones and de-phosphorylation events carried out by ...
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Article
Mitochondrial cytochrome c shot towards histone chaperone condensates in the nucleus
González Arzola, Katiuska; Guerra Castellano, Alejandra; Rivero Rodríguez, Francisco; Casado Combreras, Miguel Ángel; Pérez Mejías, Gonzalo; Díaz Quintana, Antonio Jesús; Díaz Moreno, Irene; Rosa Acosta, Miguel Ángel de la (Wiley-Blackwell, 2021)Despite mitochondria being key for the control of cell homeostasis and fate, their role in DNA damage response is usually ...
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Article
Neddylation of phosphoenolpyruvate carboxykinase 1 controls glucose metabolism
González Rellán, María J.; Fernández, Uxía; Parracho, Tamara; Novoa, Eva; Fondevila, Marcos F.; Da Silva Lima, Natalia; Rodríguez, Amaia; Pérez Mejías, Gonzalo; Díaz Quintana, Antonio Jesús; Díaz Moreno, Irene; Nogueiras, Rubén (Elsevier, 2023)Neddylation is a post-translational mechanism that adds a ubiquitin-like protein, namely neural precursor cell expressed ...
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Article
Nicotinamide N-methyltransferase (NNMT) regulates the glucocorticoid signaling pathway during the early phase of adipogenesis
Roberti, Annalisa; Tejedor, Juan Ramón; Díaz Moreno, Irene; López, Virginia; Santamarina-Ojeda, Pablo; Pérez, Raúl F.; Urdinguio, Rocío G.; Concellón, Carmen; Martínez-Chantar, María Luz; Fernández Morera, Juan Luis; Díaz Quintana, Antonio Jesús; Amo, Vicente del; Fernández, Agustín F.; Fraga, Mario F. (Springer Nature, 2023-05-22)Obesity is associated with adipose tissue dysfunction through the differentiation and expansion of pre-adipocytes to ...
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Article
Nuclear cytochrome c – a mitochondrial visitor regulating damaged chromatin dynamics
Díaz Moreno, Irene; Velázquez Cruz, Alejandro; Curran French, Seamus; Díaz Quintana, Antonio Jesús; Rosa Acosta, Miguel Ángel de la (Wiley-Blackwell, 2018)Over the past decade, evidence has emerged suggesting a broader role for cytochrome c (Cyt c) in programmed cell death. ...
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Article
Nucleus-translocated mitochondrial cytochrome c liberates nucleophosmin-sequestered ARF tumor suppressor by changing nucleolar liquid-liquid phase separation.
González Arzola, Katiuska; Díaz Quintana, Antonio Jesús; Bernardo García, Noelia; Martínez Fábregas, Jonathan; Rivero Rodríguez, Francisco; Casado Combreras, Miguel Ángel; Elena-Real, Carlos A.; Velázquez Cruz, Alejandro; Gil Caballero, Sergio; Velázquez Campoy, Adrián; Szulc, Elzbieta; Gavilán Dorronzoro, María de la Paz; Ayala, Isabel; Arranz, Rocío; Ríos, Rosa M.; Salvatella, Xavier; Valpuesta, José María; Hermoso, Juan A.; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Nature Research, 2022-10-11)The regular functioning of the nucleolus and nucleus-mitochondria crosstalk are considered unrelated processes, yet ...
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Article
Oxidative stress is tightly regulated by cytochrome c phosphorylation and respirasome factors in mitochondria
Guerra Castellano, Alejandra; Díaz Quintana, Antonio Jesús; Pérez Mejías, Gonzalo; Elena-Real, Carlos A.; González Arzola, Katiuska; García Mauriño, Sofía M.; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (National Academy of Sciences, 2018)Respiratory cytochrome c has been found to be phosphorylated at tyrosine 97 in the postischemic brain upon neuroprotective ...
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Article
Post-Translational Modifications of Cytochrome c in Cell Life and Disease
Guerra Castellano, Alejandra; Márquez Escudero, Inmaculada; Pérez Mejías, Gonzalo; Díaz Quintana, Antonio Jesús; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (MDPI, 2020)Mitochondria are the powerhouses of the cell, whilst their malfunction is related to several human pathologies, including ...
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Article
PP2A is activated by cytochrome c upon formation of a diffuse encounter complex with SET/TAF-Iβ
Casado Combreras, Miguel Ángel; Rivero Rodríguez, Francisco; Elena-Real, Carlos A.; Molodenskiy, Dmitry; Díaz Quintana, Antonio Jesús; Martinho, Marlène; Gerbaud, Guillaume; González Arzola, Katiuska; Velázquez Campoy, Adrián; Svergun, Dmitri; Belle, Valérie; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Elsevier, 2022)Intrinsic protein flexibility is of overwhelming relevance for intermolecular recognition and adaptability of highly dynamic ...
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Article
PP2A is activated by cytochrome c upon formation of a diffuse encounter complex with SET/TAF-Iβ
Casado Combreras, Miguel Ángel; Rivero Rodríguez, Francisco; Elena-Real, Carlos A.; Molodenskiy, Dmitry; Díaz Quintana, Antonio Jesús; Martinho, Marlène; Gerbaud, Guillaume; González Arzola, Katiuska; Velázquez Campoy, Adrián; Svergun, Dmitri; Belle, Valérie; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Research Network of Computational and Structural Biotechnology, 2022)Intrinsic protein flexibility is of overwhelming relevance for intermolecular recognition and adaptability of highly dynamic ...
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Article
Proposed mechanism for regulation of H2O2-induced programmed cell death in plants by binding of cytochrome c to 14-3-3 proteins
Elena-Real, Carlos A.; González Arzola, Katiuska; Pérez Mejías, Gonzalo; Díaz Quintana, Antonio Jesús; Velázquez Campoy, Adrián; Desvoyes, Bénédicte; Gutiérrez, Crisanto; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Wiley-Blackwell, 2021-04)Programmed cell death (PCD) is crucial for development and homeostasis of all multicellular organisms. In human cells, the ...
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Article
Protonation of the Cysteine Axial Ligand Investigated in His/Cys c-Type Cytochrome by UV-Vis and Mid- And Far-IR Spectroscopy
Zuccarello, Lidia; Berthomieu, Catherine; Boussac, Alain; Brubach, Jean Blaise; Díaz Moreno, Irene; Díaz Quintana, Antonio Jesús; Hienerwadel, Rainer (American Chemical Society, 2020)His/Cys coordination was recently found in several c-type cytochromes, which could act as sensors, in electron transport ...
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Article
RNA Binding Protein Regulation and Cross-Talk in the Control of AU-rich mRNA Fate
García Mauriño, Sofía M.; Rivero Rodríguez, Francisco; Velázquez Cruz, Alejandro; Hernández Vellisca, Marian; Díaz Quintana, Antonio Jesús; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Frontiers Media, 2017)mRNA metabolism is tightly orchestrated by highly-regulated RNA Binding Proteins (RBPs) that determine mRNA fate, thereby ...