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Mostrando ítems 1-4 de 4
Artículo
Biological Evaluation of Carbohydrate-based Aprepitant Analogs for Neuroblastoma Treatment
(Elsevier, 2024)
Different studies using Aprepitant, a NK1R antagonist currently used as a clinical drug for treating chemotherapy-related nausea and vomiting, have demonstrated that pharmacological inhibition of NK1R effectively reduces ...
Artículo
Lysosomes: multifunctional compartments ruled by a complex regulatory network
(Wiley, 2022)
More than 50 years have passed since Nobel laureate Cristian de Duve described for the first time the presence of tiny subcellular compartments filled with hydrolytic enzymes: the lysosome. For a long time, lysosomes were ...
Artículo
Zero-valent ML2complexes of Group 10 Metals Supported by Terphenyl Phosphanes
(Royal Society of Chemistry, 2021)
Bulky terphenyl phosphane ligands PMe2Ar′ (Ar′ = terphenyl group) facilitate the isolation of zero-valent bis-phosphane complexes of nickel, palladium and platinum. The former show coordination numbers greater than two in ...
Artículo
Biodegradable particles for protein delivery: estimation of the release kinetics inside cells
(Elsevier, 2022-08)
A methodology to quantify the efficiency of the protein loading and in-vitro delivery for biodegradable capsules with different architectures based on polyelectrolytes (dextran sulfate, poly-L-arginine and polyethylenimine) and ...