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Mostrando ítems 241-250 de 256
Artículo
Dynamic Kinetic Resolution of Indole-Based Sulfenylated Heterobiaryls by Rhodium-Catalyzed Atroposelective Reductive Aldol Reaction
(Amer chemical SOC, 2023-08-30)
A highly enantio- and diastereoselective dynamic kinetic resolution (DKR) of configurationally labile 3-aryl indole-2-carbaldehydes is described. The DKR proceeds via a Rh-catalyzed intermolecular asymmetric reductive aldol ...
Artículo
Dynamic kinetic resolution of 2-(Quinolin-8-yl)benzaldehydes: atroposelective iridium-catalyzed transfer hydrogenative allylation
(Wiley-V C H Verlag GMBH, 2023-06-30)
An atroposelective Ir-catalyzed dynamic kinetic resolution (DKR) of 2-(quinolin-8- yl)benzaldehydes/1-naphthaldehydes by transfer hydrogenative coupling of allyl acetate is disclosed. The allylation reaction takes place ...
Artículo
Excited-state dynamics in borylated arylisoquinoline complexes in solution and in cellulo
(Wiley-V C H Verlag GMBH, 2022-12-07)
Two four-coordinate organoboron N,C-chelate complexes with different functional terminals on the PEG chains are studied with respect to their photophysical properties within human MCF-7 cells. Their excited-state properties ...
Artículo
Multivalent glycosystems for human lectins
(Royal Society of Chemistry, 2022-08-30)
Human lectins are involved in a wide variety of biological processes, both physiological and pathological, which have attracted the interest of the scientific community working in the glycoscience field. Multivalent ...
Artículo
Green Oxidative Catalytic Processes for the Preparation of APIs and Precursors
(MDPI, 2023-03-22)
Asymmetric oxidation processes have constituted a valuable tool for the synthesis of active pharmaceutical ingredients (APIs), especially for the preparation of optically active sulfoxides, compounds with interesting ...
Artículo
N-Substituted 3-Aminooxindoles and N-Propargyl Derivatives: Potential Biological Activities against Alzheimer's Disease
(Elsevier, 2023-07-08)
The oxindole core is an important structural motif in many natural and synthetic substances with various biological activities including anticancer, antineurodegenerative, and antimicrobial properties. This report focuses on ...
Artículo
Silver-free gold-catalyzed heterocyclizations through intermolecular H-bonding activation.
(AMER Chemical Soc, 2023-01-27)
Modulable monosulfonyl squaramides have been shown to exert activation of gold(I) chloride complexes through H-bonding in an intermolecular way. Combinations of (PPh3)AuCl or IPrAuCl complexes and an optimal sulfonyl ...
Artículo
Asymmetric Dearomatization of Phthalazines by Anion-BindingCatalysis
(American Chemical Society, 2023-12-01)
A straightforward methodology for the enantioselective synthesis of 1,2-dihydrophthalazines via dearomatization of phthalazines by anion-binding catalysis has been developed. The process involves the Mannich-type addition ...
Artículo
Azaborahelicene fluorophores derived from four-coordinate N,C-boron chelates: synthesis, photophysical and chiroptical properties
(Royal Society of Chemistry, 2023-12-12)
A series of six azaborahelicenes with varying electron-donor substitution at the 4-position of the aryl residue (i.e., naphthyl) or with variable π-extension of the aryl residue (thianthrenyl, anthryl, pyrenyl) was prepared ...
Artículo
A selenoureido-iminoglycolipid transported by zeolitic-imidazolate framework nanoparticles: a novel antioxidant therapeutic approach
(Royal Society of Chemistry, 2023-10-05)
A selenium-containing metal–organic framework with remarkable antioxidant capacity and ROS-scavenging activity was constructed by a controlled de novo encapsulation approach of a glycoconjugate mimetic, specifically a ...