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Mostrando ítems 11-20 de 23
Artículo
Reelin Protects against Colon Pathology via p53 and May Be a Biomarker for Colon Cancer Progression
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Previous observations made in human and mouse colons suggest that reelin protects the colon from pathology. In this study, we evaluated reelin expression during the transition from either colitis or precancerous lesions ...
Artículo
Inflammatory bowel disease induces pathologicalα-synucleinaggregation in the human gut and brain
(Wiley, 2024-01-16)
Aims According to Braak's hypothesis, it is plausible that Parkinson's disease (PD) originates in the enteric nervous system (ENS) and spreads to the brain through the vagus nerve. In this work, we studied whether ...
Artículo
Reelin protects from colon pathology by maintaining the intestinal barrier integrity and repressing tumorigenic genes
(Elsevier, 2017)
We previously reported that reelin, an extracellular matrix protein first known for its key role in neuronal migration, reduces the susceptibility to dextran sulphate sodium (DSS)-colitis. The aim of the current study was ...
Artículo
Small and large intestine express a truncated Dab1 isoform that assembles in cell-cell junctions and co-localizes with proteins involved in endocytosis
(Elsevier, 2018)
Disabled-1 (Dab1) is an essential intracellular adaptor protein in the reelin pathway. Our previous studies in mice intestine showed that Dab1 transmits the reelin signal to cytosolic signalling pathways. Here, we determine ...
Artículo
Na+-dependent D-mannose transport at the apical membrane of rat small intestine and kidney cortex
(Elsevier, 2001)
The presence of a Na+/D-mannose cotransport activity in brush-border membrane vesicles (BBMV), isolated from either rat small intestine or rat kidney cortex, is examined. In the presence of an electrochemical Na+ gradient, ...
Artículo
Dab1 and reelin participate in a common signal pathway that controls intestinal crypt/villus unit dynamics
(Wiley-Blackwell, 2014)
Background information: The myofibroblasts placed underneath the epithelium of the rodent small intestine express reelin, and the reelin absence modifies both the morphology and the cell renewal processes of the crypt-villus ...
Artículo
Hormonal Regulation of chicken intestinal NHE and SGLT-1 activities
(2001)
The effects of aldosterone and arginine vasotocin (AVT) on intestinal Na/Hexchange (NHE) and Na-sugar cotransport (SGLT-1) activi-ties have been investigated using brush-border membrane ves-icles isolated from Hubbard ...
Artículo
Ontogeny regulates creatine metabolism in rat small and large intestine
(2009)
The ontogeny of intestinal CRT, AGAT and GAMT was investigated in foetuses, newborn, suckling, weaning and adult rats. In the colon, CRT mediates creatine transport because it was Na+- and Cl—dependent and inhibited by ...
Artículo
Instagram como herramienta de aprendizaje en Fisiología: @fisiofarma_us
(Real e Ilustre Colegio Oficial de Farmacéuticos, 2023)
Las redes sociales (RR.SS.) forman parte de nuestra vida diaria convirtiéndose en una de las principales vías de comunicación y búsqueda de información, especialmente entre los más jóvenes. Entre los usuarios que usan ...
Artículo
Dab2, megalin, cubilin and amnionless receptor complex might mediate intestinal endocytosis in the suckling rat
(Wiley-Blackwell, 2014)
We previously proposed that Dab2 participates in the endocytosis of milk macromolecules in rat small intestine. Here we investigate the receptors that may mediate this endocytosis by studying the effects of age and diet ...