Buscar
Mostrando ítems 1-4 de 4
Artículo
Vitamin D deficiency as a potential risk factor for accelerated aging, impaired hippocampal neurogenesis and cognitive decline: a role for Wnt/β-catenin signaling
(Impact Journals LLC, 2020)
Vitamin D is an essential fat-soluble vitamin that participates in several homeostatic functions in mammalian organisms. Lower levels of vitamin D are produced in the older population, vitamin D deficiency being ...
Artículo
Effects of classical PKC activation on hippocampal neurogenesis and cognitive performance: mechanism of action
(Springer Nature, 2021)
Hippocampal neurogenesis has widely been linked to memory and learning performance. New neurons generated from neural stem cells (NSC) within the dentate gyrus of the hippocampus (DG) integrate in hippocampal circuitry ...
Artículo
Evolution of Experimental Models in the Study of Glioblastoma: Toward Finding Efficient Treatments
(Frontiers Media, 2021)
Glioblastoma (GBM) is the most common form of brain tumor characterized by its resistance to conventional therapies, including temozolomide, the most widely used chemotherapeutic agent in the treatment of GBM. Within the ...
Artículo
Oxidative Stress as a Potential Mechanism Underlying Membrane Hyperexcitability in Neurodegenerative Diseases
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Neurodegenerative diseases are characterized by gradually progressive, selective loss of anatomically or physiologically related neuronal systems that produce brain damage from which there is no recovery. Despite the ...