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Artículo
A metagenome-wide association study of HIV disease progression in HIV controllers
(Elsevier, 2023)
Some HIV controllers experience immunologic progression with CD4+ T cell decline. We aimed to identify genetic factors associated with CD4+ T cell lost in HIV controllers. A total of 561 HIV controllers were included, 442 ...
Artículo
Pancreas fat content, insulin homeostasis and circulating endothelial microparticles in male essential hypertensive patients
(Wiley Open Access, 2022-10-16)
Thepancreasfatcontenthasbeenpoorlyinvestigatedinessentialhypertension.Theauthorsaimtorelatepancreasandliverfatcontentwithparametersmeasuringinsulinresistance, beta-cell function and also with markers of endothelial dysfunction ...
Artículo
Similar incidence of coronavirus disease 2019 (COVID-19) in patients with rheumatic diseases with and without hydroxychloroquine therapy
(Public Library of Science, 2021)
Background Hydroxychloroquine is not efficacious as post-exposure prophylaxis against coronavirus disease 2019 (COVID-19). It is not known whether as pre-exposure prophylaxis it may prevent COVID-19. Objective To compare ...
Artículo
Evaluation of aquaporins in the cerebrospinal fluid in patients with idiopathic normal pressure hydrocephalus
(PLOS, 2021)
Brain aquaporin 1 (AQP1) and AQP4 are involved in cerebrospinal fluid (CSF) homeostasis and might participate in the origin of hydrocephalus. Studies have shown alterations of perivascular AQP4 expression in idiopathic ...
Artículo
Controlled attenuation parameter-insulin resistance (CIR) score to predict non-alcoholic steatohepatitis
(Nature Research, 2022-12-19)
The diagnosis of non-alcoholic steatohepatitis (NASH) requires liver biopsy. Patients with NASH are at risk of progression to advanced fibrosis and hepatocellular carcinoma. A reliable non-invasive tool for the detection ...
Artículo
Response to glecaprevir/pibrentasvir in HIV/HCV-coinfected patients in clinical practice
(Oxford University Press, 2023-09-06)
HIV infection has been associated with lower rates of sustained viral response (SVR) with direct-acting antivirals (DAAs). There are few data on glecaprevir/pibrentasvir (G/P) in HIV/HCV coinfection outside clinical trials.
Artículo
High efficacy of glecaprevir/pibrentasvir for HCV-infected individuals with active drug use
(Elsevier, 2022-09)
Objectives Real world data on glecaprevir/pibrentasvir (G/P) among active drug users are scarce. We evaluated the sustained virological response (SVR) rates of G/P among individuals with and without active drug use in ...
Artículo
Hepatic Steatosis and Weight Gain During the Coronavirus Disease 2019 Pandemic Among People With Human Immunodeficiency Virus: Impact of Therapy With Tenofovir Alafenamide
(Oxford University Press, 2023-10-31)
Lockdown due to the coronavirus disease 2019 (COVID-19) pandemic led to increases in weight in part of the population. Weight gain leads to hepatic steatosis (HS). Antiretroviral treatment could also influence HS in people ...