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Artículo
Vitamin D deficiency as a potential risk factor for accelerated aging, impaired hippocampal neurogenesis and cognitive decline: a role for Wnt/β-catenin signaling
(Impact Journals LLC, 2020)
Vitamin D is an essential fat-soluble vitamin that participates in several homeostatic functions in mammalian organisms. Lower levels of vitamin D are produced in the older population, vitamin D deficiency being ...
Artículo
Migratory Response of Cells in Neurogenic Niches to Neuronal Death: The Onset of Harmonic Repair?
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
Harmonic mechanisms orchestrate neurogenesis in the healthy brain within specific neurogenic niches, which generate neurons from neural stem cells as a homeostatic mechanism. These newly generated neurons integrate into ...
Artículo
Effects of classical PKC activation on hippocampal neurogenesis and cognitive performance: mechanism of action
(Springer Nature, 2021)
Hippocampal neurogenesis has widely been linked to memory and learning performance. New neurons generated from neural stem cells (NSC) within the dentate gyrus of the hippocampus (DG) integrate in hippocampal circuitry ...
Artículo
Targeting epidermal growth factor receptor to recruit newly generated neuroblasts in cortical brain injuries
(BMC, 2023-11-30)
Background Neurogenesis is stimulated in the subventricular zone (SVZ) of mice with cortical brain injuries. In most of these injuries, newly generated neuroblasts attempt to migrate toward the injury, accumulating within ...
Artículo
Rescue of neurogenesis and age-associated cognitive decline in SAMP8 mouse: Role of transforming growth factor-alpha
(Wiley Open Access, 2023-03-19)
Neuropathological aging is associated with memory impairment and cognitive decline, affecting several brain areas including the neurogenic niche of the dentate gyrus of the hippocampus (DG). In the healthy brain, ...