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Artículo
Reelin expression is up-regulated in mice colon in response to acute colitis and provides resistance against colitis
(Elsevier, 2017)
Reelin is an extracellular matrix protein first known for its key role in neuronal migration. Studies in rodent small intestine suggested that reelin protects the organism from intestinal pathology. Here we determined in ...
Artículo
Reelin Protects against Colon Pathology via p53 and May Be a Biomarker for Colon Cancer Progression
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Previous observations made in human and mouse colons suggest that reelin protects the colon from pathology. In this study, we evaluated reelin expression during the transition from either colitis or precancerous lesions ...
Artículo
Reelin protects from colon pathology by maintaining the intestinal barrier integrity and repressing tumorigenic genes
(Elsevier, 2017)
We previously reported that reelin, an extracellular matrix protein first known for its key role in neuronal migration, reduces the susceptibility to dextran sulphate sodium (DSS)-colitis. The aim of the current study was ...
Artículo
Dab1 and reelin participate in a common signal pathway that controls intestinal crypt/villus unit dynamics
(Wiley-Blackwell, 2014)
Background information: The myofibroblasts placed underneath the epithelium of the rodent small intestine express reelin, and the reelin absence modifies both the morphology and the cell renewal processes of the crypt-villus ...
Artículo
Lack of reelin modifies the gene expression in the small intestine of mice
(Springer Nature, 2012)
We recently demonstrated that the mucosa of the small intestine of the rat expresses reelin and some components of its signaling system. The current study evaluates whether reelin affects the intestinal gene expression ...
Artículo
Reelin-Dab1 signaling system in human colorectal cancer
(Wiley-Blackwell, 2017)
Reelin is an extracellular matrix protein that plays a critical role in neuronal migration. Here we show that the mucosa of human colon expresses reelin, its receptors ApoER2 and VLDLR, and its effector protein Dab1. ...