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Mostrando ítems 1-10 de 13
Artículo
Purkinje cell-specific Grip1/2 knockout mice show increased repetitive self-grooming and enhanced mGluR5 signaling in cerebellum
(Elsevier, 2019)
Cerebellar Purkinje cell (PC) loss is a consistent pathological finding in autism. However, neural mechanisms of PC-dysfunction in autism remain poorly characterized. Glutamate receptor interacting proteins 1/2 (Grip1/2) ...
Artículo
Antiproliferative effect of boldine on neural progenitor cells and on glioblastoma cells
(Frontiers Media, 2023)
The subventricular zone (SVZ) is a brain region that contains neural stem cells and progenitor cells (NSCs/NPCs) from which new neurons and glial cells are formed during adulthood in mammals. Recent data indicate that ...
Artículo
Folic Acid Antioxidant Supplementation to Binge Drinking Adolescent Rats Improves Hydric-saline Balance and Blood Pressure, but Fails to Increase Renal NO Availability and Glomerular Filtration Rate
(Wiley, 2023)
Binge drinking (BD) is an especially pro-oxidant pattern of alcohol consumption, particularly widespread in the adolescent population. In the kidneys, it affects the glomerular filtration rate (GFR), leading to high blood ...
Artículo
Hypertension secondary to nitric oxide depletion produces oxidative imbalance and inflammatory/fibrotic outcomes in the cornea of C57BL/6 mice.
(Springer, 2022)
Arterial hypertension (AH) leads to oxidative and infammatory imbalance that contribute to fbrosis development in many target organs. Here, we aimed to highlight the harmful efects of severe AH in the cornea. Our experimental ...
Artículo
Manipulation of Amino Acid Levels with Artificial Diets Induces a Marked Anticancer Activity in Mice with Renal Cell Carcinoma
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Targeted therapies with antiangiogenic drugs (e.g., sunitinib) and immune checkpoint inhibitors (e.g., anti-PD-1 antibodies) are the standard of care for patients with metastatic renal cell carcinoma. Although these ...
Artículo
Characterization of emissions of condensable particulate matter under real operation conditions in cement clinker kilns using complementary experimental techniques
(Elsevier, 2021-09)
Historically, the emission of particles from clinker kiln stacks has been one of the main environmental concerns in cement manufacturing processes. Up to now, environmental regulations have only focused on determining and ...
Artículo
Dysregulation of the Hippo Pathway Signaling in Aging and Cancer
(Elsevier, 2019)
Human beings are facing emerging degenerative and cancer diseases, in large part, as a consequence of increased life expectancy. In the near future, researchers will have to put even more effort into fighting these new ...
Artículo
Artículo
Microbiota-liver-bile salts axis, a novel mechanism involved in the contrasting effects of sodium selenite and selenium-nanoparticle supplementation on adipose tissue development in adolescent rats
(MDPI, 2023)
Adolescence is a period during which body composition changes deeply. Selenium (Se) is an excellent antioxidant trace element related to cell growth and endocrine function. In adolescent rats, low Se supplementation affects ...
Artículo
FarmaEscape El Retorno: el empleo de una Escape Room como herramienta de aprendizaje en los estudios de la Facultad de Farmacia de la Universidad de Sevilla
(Real e Ilustre Colegio Oficial de Farmacéuticos, 2023)
Una Escape Room es un juego de escapismo en el que un grupo de personas están “atrapadas” en una sala cerrada, debiendo resolver una serie de enigmas o pruebas para conseguir “escapar” en un tiempo menor del estipulado. ...