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Mostrando ítems 1-10 de 13
Artículo
Reelin expression is up-regulated in mice colon in response to acute colitis and provides resistance against colitis
(Elsevier, 2017)
Reelin is an extracellular matrix protein first known for its key role in neuronal migration. Studies in rodent small intestine suggested that reelin protects the organism from intestinal pathology. Here we determined in ...
Artículo
The Synaptojanins in the murine small and large intestine
(Springer Nature, 2016)
The expression of the phosphoinositides phosphatases Synaptojanins (Synjs) 1 and 2 has been shown in brain and in some peripheral tissues, but their expression in the intestine has not been reported. Herein we show that ...
Artículo
Artículo
Na+/Cl-/creatine transporter activity and expression in rat brain synaptosomes
(Elsevier, 2010)
Creatine is involved in brain ATP homeostasis and it may also act as neurotransmitter. Creatine transport was measured in synaptosomes obtained from the diencephalon and telencephalon of suckling and 2 month-old rats. ...
Artículo
Regulation of Dab2 expression in intestinal and renal epithelia by development
(Wiley-Blackwell, 2011)
Disabled-2 (Dab2) is an intracellular adaptor protein proposed to function in endocytosis. Here, we investigate the intestinal and renal Dab2 expression versus maturation. Dab2 mRNA levels measured by RT-PCR are greater ...
Artículo
Reelin protects from colon pathology by maintaining the intestinal barrier integrity and repressing tumorigenic genes
(Elsevier, 2017)
We previously reported that reelin, an extracellular matrix protein first known for its key role in neuronal migration, reduces the susceptibility to dextran sulphate sodium (DSS)-colitis. The aim of the current study was ...
Artículo
Small and large intestine express a truncated Dab1 isoform that assembles in cell-cell junctions and co-localizes with proteins involved in endocytosis
(Elsevier, 2018)
Disabled-1 (Dab1) is an essential intracellular adaptor protein in the reelin pathway. Our previous studies in mice intestine showed that Dab1 transmits the reelin signal to cytosolic signalling pathways. Here, we determine ...
Artículo
Dab1 and reelin participate in a common signal pathway that controls intestinal crypt/villus unit dynamics
(Wiley-Blackwell, 2014)
Background information: The myofibroblasts placed underneath the epithelium of the rodent small intestine express reelin, and the reelin absence modifies both the morphology and the cell renewal processes of the crypt-villus ...
Artículo
Dab2, megalin, cubilin and amnionless receptor complex might mediate intestinal endocytosis in the suckling rat
(Wiley-Blackwell, 2014)
We previously proposed that Dab2 participates in the endocytosis of milk macromolecules in rat small intestine. Here we investigate the receptors that may mediate this endocytosis by studying the effects of age and diet ...
Artículo
Na+-dependent and Na+-independent betaine transport across the apical membrane of rat renal epithelium
(Elsevier, 2015)
The low renal excretion of betaine indicates that the kidney efficiently reabsorbs the betaine filtered by the glomeruli but the mechanisms involved in such a process have been scarcely investigated. We have detected ...