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Mostrando ítems 21-30 de 201
Artículo
Arginine deprivation alters microglial polarity and synergizes with radiation to eradicate non-arginine-auxotrophic glioblastoma tumors
(American Society for Clinical Investigation, 2022)
New approaches for the management of glioblastoma (GBM) are an urgent and unmet clinical need. Here, we illustrate that the efficacy of radiotherapy for GBM is strikingly potentiated by concomitant therapy with the ...
Artículo
La utilización de bases de datos como herramientas de evaluación
(Universidad de Sevilla. SAV, 1996)
En este artículo se comprueba la validez de utilización de las bases de datos para elaborar pruebas objetivas. Al comparar distintos grupos no se han encontrado diferencias estadísticamente significativas entre los alumnos ...
Artículo
A protocol to enrich in undifferentiated cells from neuroblastoma tumor tissue samples and cell lines
(Cell Press, 2022)
The existence of a subpopulation of undifferentiated cells with stem-like properties has been suggested in neuroblastoma tumors, but a definitive biomarker for their successful isolation is missing. Here we describe an in ...
Artículo
A microRNA expression signature of the postprandial state in response to a high-saturated-fat challenge
(Elsevier, 2018)
The postprandial hypertriglyceridemia is an important and largely silent disturbance involved in the genesis of numerous pathological conditions. Exaggerated and prolonged states of postprandial hypertriglyceridemia are ...
Artículo
Effect of protein kinase a activity on the association of ADP-ribosylation factor 1 to Golgi membranes
(The American Society for Biochemistry and Molecular Biology, 2000)
The small GTP-binding protein ADP-ribosylation factor 1 (ARF1) is an essential component of the molecular machinery that catalyzes the formation of membranebound transport intermediates. By using an in vitro assay that ...
Artículo
Effect of metabolites of hydroxytyrosol on protection against oxidative stress and inflammation in human endothelial cells
(Elsevier, 2017)
The effects of chemically synthesized metabolites (sulfate and glucuronate forms) from hydroxytyrosol (HTyr) on oxidative stress and inflammation were investigated in TNF-α-activated human endothelial cells. HTyr sulfate ...
Artículo
CD44 Acts as a Coreceptor for Cell-specific Enhancement of Signaling and Regulatory T Cell Induction by TGM1, a Parasite TGF-β Mimic
(National Academy of Sciences, 2023)
Long-lived parasites evade host immunity through highly evolved molecular strategies. The murine intestinal helminth, Heligmosomoides polygyrus, down-modulates the host immune system through release of an immunosuppressive ...
Artículo
Artículo
An opinion on the regulation of bone marrow adipose tissue by dietary fatty acids
(CSIC, 2020)
Obesity has a significant impact on predisposition to various diseases and also affects the viability and choice of haematopoietic stem cells (HSCs) to favour myeloid cell production and/or turnover, all of which are ...