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Artículo
Tyrosol and its metabolites as antioxidative and anti-inflammatory molecules in human endothelial cells
(Royal Society of Chemistry, 2017)
Tyrosol (Tyr) is a phenolic compound found in virgin olive oil. After ingestion, Tyr undergoes extensive first pass intestinal/hepatic metabolism. However, knowledge about the biological effects of Tyr metabolites is scarce. ...
Tesis Doctoral
Histofisiología del epitelio renal de helix aspersa (mollusca, gastropoda, pulmonata, stylommatophora)
(1983)
La excreción es, por definición, la separación de los productos de desecho de los fluidos tisulares y corporales, y su eliminación del organismo. Además, se considera como el resultado de la filtración del líquido de la ...
Tesis Doctoral
Estudio de la familia de proteínas Rho GTPasas en la biología del neuroblastoma
(2022-07-14)
El neuroblastoma (NB) es el tumor extracraneal sólido de aparición más común durante la edad pediátrica. El NB surge a raíz de un desarrollo erróneo del linaje simpatoadrenal de la cresta neural. Es una enfermedad muy ...
Artículo
The Cockayne syndrome protein B is involved in the repair of 5-AZA-2′-deoxycytidine-induced DNA lesions
(Impact Journals, 2018)
The Cockayne Syndrome Protein B (CSB) plays an essential role in Transcription-Coupled Nucleotide Excision Repair (TC-NER) by recruiting repair proteins once transcription is blocked with a DNA lesion. In fact, CSB-deficient ...
Artículo
The yeast p24 complex regulates gpi-anchored protein Transport and quality control by monitoring anchor remodeling
(American Society for Cell Biology, 2011)
Glycosylphosphatidylinositol (GPI)-anchored proteins are secretory proteins that are attached to the cell surface of eukaryotic cells by a glycolipid moiety. Once GPI anchoring has occurred in the lumen of the endoplasmic ...
Artículo
RENEB – Running the European Network of biological dosimetry and physical retrospective dosimetry
(Taylor & Francis, 2017)
Purpose: A European network was initiated in 2012 by 23 partners from 16 European countries with the aim to significantly increase individualized dose reconstruction in case of large-scale radiological emergency ...
Artículo
RENEB Inter-Laboratory Comparison 2021: The Dicentric Chromosome Assay
(Radiation Research Society, 2023)
After large-scale radiation accidents where many individuals are suspected to be exposed to ionizing radiation, biological and physical retrospective dosimetry assays are important tools to aid clinical decision making by ...
Artículo
Dual Independent Roles of the p24 Complex in Selectivity of Secretory Cargo Export from the Endoplasmic Reticulum
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)
The cellular mechanisms that ensure the selectivity and fidelity of secretory cargo protein transport from the endoplasmic reticulum (ER) to the Golgi are still not well understood. The p24 protein complex acts as a specific ...
Artículo
Olive oil and postprandial hyperlipidemia: Implications for atherosclerosis and metabolic syndrome
(Royal Society of Chemistry, 2016)
Olive oil is the primary source of fat in the Mediterranean diet, which is associated with a significant improvement in health status, as measured by reduced mortality from several chronic diseases. The current pandemic ...
Artículo
Cells Deficient in the Fanconi Anemia Protein FANCD2 are Hypersensitive to the Cytotoxicity and DNA Damage Induced by Coffee and Caffeic Acid
(MDPI AG, 2016)
Epidemiological studies have found a positive association between coffee consumption and a lower risk of cardiovascular disorders, some cancers, diabetes, Parkinson and Alzheimer disease. Coffee consumption, however, has ...