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Listar por autor "Roca Ceballos, María Angustias"  

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    • Tesis Doctoral
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      Caracterización del modelo condicional neuronal de caspasa 3 en condiciones fisiológicas y patológicas 

      Roca Ceballos, María Angustias (2022-12-02)
      La caspasa 3 (casp 3) es una proteasa ampliamente conocida por su papel clave como mediadora en la apoptosis neuronal. ...
    • Artículo
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      Galectin‑3, a novel endogenous TREM2 ligand, detrimentally regulates infammatory response in Alzheimer’s disease 

      Boza Serrano, Antonio; Ruíz Laza, Rocio; Sánchez Varo, Raquel María; García Revilla, Juan; Yang, Yiyi; Jiménez Ferrer, Itzia; Jiménez Muñoz, Sebastián; Roca Ceballos, María Angustias; Navarro Garrido, Victoria; Vitorica Ferrández, Francisco Javier; Venero Recio, José Luis; Deierborg, Tomas (Springer, 2019)
      Alzheimer’s disease (AD) is a progressive neurodegenerative disease in which the formation of extracellular aggregates of ...
    • Artículo
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      HERC1 Ubiquitin Ligase Is Required for Normal Axonal Myelination in the Peripheral Nervous System 

      Bachiller, Sara; Roca Ceballos, María Angustias; García Domínguez, Irene; Pérez Villegas, Eva María; Martos Carmona, David; Pérez Castro, Miguel Ángel; Real Navarrete, Luis Miguel; Rosa, José Luis; Tabares, Lucía; Venero Recio, José Luis; Armengol, José Ángel; Carrión, Ángel Manuel; Ruiz Laza, Rocío (Springer, 2018-03-30)
      A missense mutation in HERC1 provokes loss of cerebellar Purkinje cells, tremor, and unstable gait in tambaleante (tbl) ...
    • Artículo
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      Inflammatory bowel disease induces pathologicalα-synucleinaggregation in the human gut and brain 

      Espinosa Oliva, Ana María; Ruiz Laza, Rocío; Sarmiento Soto, Manuel; Boza Serrano, Antonio; Rodríguez Pérez, Ana I; Roca Ceballos, María Angustias; García Revilla, Juan; Santiago Pavón, Martiniano; Carvajal Vázquez, Ana Eloísa; Vázquez Carretero, María Dolores; García Miranda, Pablo; Oliva Martin, María José; Machado Quintana, Alberto; Peral Rubio, María José; Herrera Carmona, Antonio José; Venero Recio, José Luis; Martínez de Pablos, Rocío; neuroinflammation (Wiley, 2024-01-16)
      Aims According to Braak's hypothesis, it is plausible that Parkinson's disease (PD) originates in the enteric nervous ...
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      Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson’s Disease 

      García Domínguez, Irene; Veselá, Karolina; García Revilla, Juan; Carrillo Jiménez, Alejandro; Roca Ceballos, María Angustias; Santiago Pavón, Martiniano; Martínez de Pablos, Rocío; Venero Recio, José Luis (Frontiers Media, 2018)
      The impact of systemic inflammation in nigral dopaminergic cell loss remains unclear. Here, we have investigated the role ...
    • Artículo
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      Reformulating Pro-Oxidant Microglia in Neurodegeneration 

      García Revilla, Juan; Alonso Bellido, Isabel María; Burguillos García, Miguel Ángel; Herrera Carmona, Antonio José; Espinosa Oliva, Ana María; Ruiz Laza, Rocío; Cruz Hernández, Luis; García Domínguez, Irene; Roca Ceballos, María Angustias; Santiago Pavón, Martiniano; Rodríguez Gómez, José Antonio; Sarmiento Soto, Manuel; Martínez de Pablos, Rocío; Venero Recio, José Luis (MDPI, 2019)
      In neurodegenerative diseases, microglia-mediated neuroinflammation and oxidative stress are central events. Recent ...
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      Selective deletion of Caspase-3 gene in the dopaminergic system exhibits autistic-like behaviour 

      García Domínguez, Irene; Suárez Pereira, Irene; Santiago Pavón, Martiniano; Pérez Villegas, Eva M.; Bravo, Lidia; López Martín, Carolina; Roca Ceballos, María Angustias; García Revilla, Juan; Espinosa Oliva, Ana María; Rodríguez Gómez, José Antonio; Joseph, Bertrand; Berrocoso, Esther; Armengol, José Ángel; Venero Recio, José Luis; Ruiz Laza, Rocío; Martínez de Pablos, Rocío (Elsevier, 2021-01-10)
      Apoptotic caspases are thought to play critical roles in elimination of excessive and non-functional synapses and removal ...