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Listar por autor "Pérez Villegas, Eva María"  

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      HERC 1 Ubiquitin Ligase Mutation Affects Neocortical, CA3 Hippocampal and Spinal Cord Projection Neurons: An Ultrastructural Study 

      Ruiz Laza, Rocío; Pérez Villegas, Eva María; Bachiller, Sara; Rosa, José Luis; Armengol, Jose Ángel (Frontiers Media, 2016)
      The spontaneous mutation tambaleante is caused by the Gly483Glu substitution in the highly conserved N terminal RCC1-like ...
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      HERC1 Ubiquitin Ligase Is Required for Hippocampal Learning and Memory 

      Pérez Villegas, Eva María; Pérez Rodríguez, Mikel; Negrete Díaz, José V.; Ruiz Laza, Rocío; Rosa, José Luis; Álvarez de Toledo, Guillermo; Rodríguez Moreno, Antonio; Armengol, José Ángel (Frontiers Media, 2020)
      Mutations in the human HERC1 E3 ubiquitin ligase protein develop intellectual disability. The tambaleante (tbl) mouse ...
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      HERC1 Ubiquitin Ligase Is Required for Normal Axonal Myelination in the Peripheral Nervous System 

      Bachiller, Sara; Roca Ceballos, María Angustias; García Domínguez, Irene; Pérez Villegas, Eva María; Martos Carmona, David; Pérez Castro, Miguel Ángel; Real Navarrete, Luis Miguel; Rosa, José Luis; Tabares, Lucía; Venero Recio, José Luis; Armengol, José Ángel; Carrión, Ángel Manuel; Ruiz Laza, Rocío (Springer, 2018-03-30)
      A missense mutation in HERC1 provokes loss of cerebellar Purkinje cells, tremor, and unstable gait in tambaleante (tbl) ...
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      The Absence of Caspase-8 in the Dopaminergic System Leads to Mild Autism-like Behavior 

      Suárez Pereira, Irene; García Domínguez, Irene; Bravo, L.; Santiago Pavón, Martiniano; García Revilla, Juan; Espinosa Oliva, Ana María; Alonso Bellido, Isabel María; López Martín, César; Pérez Villegas, Eva María; Armengol, J. A.; Berrocoso, E.; Venero Recio, José Luis; Martínez de Pablos, Rocío; Ruiz Laza, Rocío (Frontiers Media S.A., 2022)
      In the last decade, new non-apoptotic roles have been ascribed to apoptotic caspases. This family of proteins plays an ...
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      The HERC proteins and the nervous system 

      Pérez Villegas, Eva María; Ruiz Laza, Rocío; Bachiller, Sara; Ventura, Francesc; Armengol, Jose A.; Rosa, Jose Luis (Elsevier, 2021)
      The HERC protein family is one of three subfamilies of Homologous to E6AP C-terminus (HECT) E3 ubiquitin ligases. Six HERC ...
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      The HERC1 ubiquitin ligase regulates presynaptic membrane dynamics of central synapses 

      Montes Fernández, María de los Ángeles; Pérez Villegas, Eva María; García-Gonzalo, Francesc R.; Pedrazza, Leonardo; Rosa, José Luis; Álvarez de Toledo Naranjo, Guillermo; Armengol, José Ángel (Nature Research, 2020-07-21)
      HERC1 is a ubiquitin ligase protein, which, when mutated, induces several malformations and intellectual disability in ...
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      The Ubiquitin Proteasome System in Neuromuscular Disorders: Moving Beyond Movement 

      Bachiller, Sara; Alonso Bellido, Isabel María; Real, Luis Miguel; Pérez Villegas, Eva María; Venero Recio, José Luis; Deierborg, Tomas; Armengol, José Ángel; Ruiz Laza, Rocío (Multidisciplinary Digital Publishing Institute (MDPI), 2020)
      Neuromuscular disorders (NMDs) affect 1 in 3000 people worldwide. There are more than 150 different types of NMDs, where ...