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      Inhibition of the NLRP3 inflammasome prevents ovarian aging 

      Navarro Pando, José Manuel; Alcocer-Gómez, Elísabet; Castejón Vega, Beatriz; Navarro Villarán, Elena; Condés Hervás, Mónica; Mundi Roldán, María; Muntané Relat, Jordi; Pérez Pulido, Antonio J.; Bullon, Pedro; Wang, Chun; Hoffman, Hal M.; Sanz Montero, Alberto; Mbalaviele, Gabriel; Ryffel, Bernhard; Cordero, Mario D. (American Association for the Advancement of Science, 2021)
      Inflammation is a hallmark of aging and is negatively affecting female fertility. In this study, we evaluate the role of ...
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      L-arginine ameliorates defective autophagy in GM2 gangliosidoses by mTOR modulation 

      Castejón Vega, Beatriz; Rubio Valle, Alejandro; Pérez Pulido, Antonio J.; Quiles Morales, José Luis; Lane, Jon D.; Fernández Domínguez, Beatriz; Alcocer-Gómez, Elísabet; Cordero, Mario D. (MDPI, 2021)
      Aims: Tay–Sachs and Sandhoff diseases (GM2 gangliosidosis) are autosomal recessive disorders of lysosomal function that ...
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      Pantothenate Rescues Iron Accumulation in Pantothenate Kinase-Associated Neurodegeneration Depending on the Type of Mutation 

      Álvarez Córdoba, Mónica; Fernández Khoury, Aida; Villanueva Paz, Marina; Gómez Navarro, Carmen; Villalón García, Irene; Suárez Rivero, Juan M.; Povea Cabello, Suleva; Mata, Mario de la; Cotán, David; Talaverón Rey, Marta; Pérez Pulido, Antonio J.; Salas, Joaquín J.; Pérez Villegas, Eva Mª; Díaz Quintana, Antonio Jesús; Armengol, José A.; Sánchez Alcázar, José A. (Springer Nature, 2019)
      Neurodegeneration with brain iron accumulation (NBIA) is a group of inherited neurologic disorders in which iron accumulates ...