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Listar por autor "Ortega Moreno, Pedro"
Mostrando ítems 1-9 de 9
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Artículo
A CDK-regulated chromatin segregase promoting chromosome replication
Chacin, Erika; Bansal, Priyanka; Reusswig, Karl-Uwe; Díaz Santín, Luis M.; Ortega Moreno, Pedro; Vizjak, Petra; Gómez González, Belén; Müller-Planitz, Felix; Aguilera López, Andrés; Pfander, Boris; Cheung, Alan C. M.; Kurat, Christoph F. (Springer Nature, 2021)The replication of chromosomes during S phase is critical for cellular and organismal function. Replicative stress can ...
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Artículo
A new role for Rrm3 in repair of replication-born DNA breakage by sister chromatid recombination
Muñoz Galván, Sandra; García Rubio, María Luisa; Ortega Moreno, Pedro; Ruiz Pérez, José Francisco; Jimeno González, Sonia; Pardo, Benjamín; Gómez González, Belén; Aguilera López, Andrés (Public Library of Science, 2017)Replication forks stall at different DNA obstacles such as those originated by transcription. Fork stalling can lead to ...
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Capítulo de Libro
Analysis of repair of replication-born double-strand breaks by sister chromatid recombination in yeast
Gómez González, Belén; Ortega Moreno, Pedro; Aguilera López, Andrés (Elsevier, 2021)The repair of DNA double-strand breaks is crucial for cell viability and the maintenance of genome integrity. When present, ...
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Artículo
Dna-rna hybrids at dsbs interfere with repair by homologous recombination
Ortega Moreno, Pedro; Mérida Cerro, José Antonio; García Rondón, Ana; Gómez González, Belén; Aguilera López, Andrés (eLife Sciences Publications, 2021)DNA double-strand breaks (DSBs) are the most harmful DNA lesions and their repair is crucial for cell viability and genome ...
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Artículo
Heterogeneity of DNA damage incidence and repair in different chromatin contexts
Ortega Moreno, Pedro; Gómez González, Belén María; Aguilera López, Andrés (Elsevier, 2021)It has been long known that some regions of the genome are more susceptible to damage and mutagenicity than others. Recent ...
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Artículo
Histone deacetylases facilitate the accurate repair of broken forks
Gómez González, Belén; Ortega Moreno, Pedro; Aguilera López, Andrés (Taylor & Francis, 2020)We have recently uncovered that loss of the yeast histone deacetylases Rpd3 (Reduced Potassium Dependency 3) and Hda1 ...
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Artículo
Histone H3E73Q and H4E53A mutations cause recombinogenic DNA damage
Ortega Moreno, Pedro; García Pichardo, Desiré; San Martín Alonso, Marta; García Rondón, Ana; Gómez González, Belén; Aguilera López, Andrés (Shared Science Publishers OG, 2020)The stability and function of eukaryotic genomes is closely linked to histones and to chromatin structure. The state of ...
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Tesis Doctoral
Influence of chromatin factors and DNA-RNA hybrids in the repair of replication-born DSBs
Ortega Moreno, Pedro (2021-06-02)La información genética debe estar almacenada de manera segura en la molécula de ADN. Sin embargo, el ADN está continuamente ...
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Artículo
Rpd3L and Hda1 histone deacetylases facilitate repair of broken forks by promoting sister chromatid cohesion
Aguilera López, Andrés; Gómez González, Belén; Ortega Moreno, Pedro (Nature Research, 2019)Genome stability involves accurate replication and DNA repair. Broken replication forks, such as those encountering a nick, ...