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Listar por autor "Jimeno González, Sonia"
Mostrando ítems 1-19 de 19
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Artículo
A new role for Rrm3 in repair of replication-born DNA breakage by sister chromatid recombination
Muñoz Galván, Sandra; García Rubio, María Luisa; Ortega Moreno, Pedro; Ruiz Pérez, José Francisco; Jimeno González, Sonia; Pardo, Benjamín; Gómez González, Belén; Aguilera López, Andrés (Public Library of Science, 2017)Replication forks stall at different DNA obstacles such as those originated by transcription. Fork stalling can lead to ...
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Artículo
ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair
Jimeno González, Sonia; Prados Carvajal, Rosario; Fernández Ávila, María Jesús; Pinela Da Silva, Sonia Cristina; Silvestris, Domenico Alessandro; Endara Coll, Martin; Rodríguez Real, Guillermo; Domingo Prim, Judit; Mejías Navarro, Fernando; Romero Franco, Amador; Jimeno González, Silvia; Barroso, Sonia; Cesarini, Valeriana; Aguilera López, Andrés; Gallo, Angela; Visa, Neus; Huertas Sánchez, Pablo (Nature Publishing Group, 2021)The maintenance of genomic stability requires the coordination of multiple cellular tasks upon the appearance of DNA ...
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Artículo
CtIP Mutations Cause Seckel and Jawad Syndromes
Qvist, Per; Huertas Sánchez, Pablo; Jimeno González, Sonia; Nyegaard, Mette; Hassan, Muhammad J.; Jackson, Stephen P. (Public Library of Science, 2011)Seckel syndrome is a recessively inherited dwarfism disorder characterized by microcephaly and a unique head profile. ...
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Artículo
EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks
Domingo Prim, Judit; Endara Coll, Martin; Bonath, Franziska; Prados Carvajal, Rosario; Friedländer, Marc R.; Visa, Neus; Huertas Sánchez, Pablo; Jimeno González, Sonia (Nature Research, 2019)The exosome is a ribonucleolytic complex that plays important roles in RNA metabolism. Here we show that the exosome is ...
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Artículo
Histone H3K56 Acetylation, Rad52, and Non-DNA Repair Factors Control Double-Strand Break Repair Choice with the Sister Chromatid
Muñoz Galván, Sandra; Jimeno González, Sonia; Rothstein, Rodney; Aguilera López, Andrés (Public Library of Science, 2013)DNA double-strand breaks (DSBs) are harmful lesions that arise mainly during replication. The choice of the sister chromatid ...
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Tesis Doctoral
Molecular basis of Aicardi-Goutières syndrome
Moó Bajo, Andrea (2023-09-21)DNA is an essential molecule for the proper functioning of the cell that is constantly exposed to exogenous and endogenous ...
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Artículo
Molecular evidence that the eukaryotic THO/TREX complex is required for efficient transcription elongation
García Rondón, Ana; Jimeno González, Sonia; García Rubio, María Luisa; Aguilera López, Andrés (American Society for Biochemistry and Molecular Biology Inc., 2003)THO/TREX is a conserved eukaryotic complex formed by the core THO complex plus proteins involved in mRNA metabolism and ...
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Artículo
N7-methylguanosine methylation of tRNAs regulates survival to stress in cancer
García Vílchez, Raquel; Añazco Guenkova, Ana M.; López, Judith; Dietmann, Sabine; Tomé, Mercedes; Jimeno González, Sonia; Azkargorta, Mikel; Elortza, Félix; Bárcena, Laura; Huertas Sánchez, Pablo; Blanco, Sandra (Springer Nature, 2023)Tumour progression and therapy tolerance are highly regulated and complex processes largely dependent on the plasticity ...
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Artículo
Neddylation inhibits CtIP-mediated resection and regulates DNA double strand break repair pathway choice
Jimeno González, Sonia; Fernández Ávila, María Jesús; Cruz García, Andrés; Cepeda García, Cristina; Gómez Cabello, Daniel; Huertas Sánchez, Pablo (Oxford University Press, 2015)DNA double strand breaks are the most cytotoxic lesions that can occur on the DNA. They can be repaired by different ...
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Artículo
New suppressors of THO mutations identify Thp3 (Ypr045c)-Csn12 as a protein complex involved in transcription elongation
Jimeno González, Sonia; Tous Rivera, Cristina; García Rubio, María Luisa; Ranes, Michael; González Aguilera, Cristina; Marín Rodríguez, Antonio; Aguilera López, Andrés (American Society for Microbiology, 2011)Formation of a ribonucleoprotein particle (mRNP) competent for export requires the coupling of transcription with mRNA ...
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Artículo
New tools to study DNA double-strand break repair pathway choice
Gómez Cabello, Daniel; Jimeno González, Sonia; Fernández Ávila, María Jesús; Huertas Sánchez, Pablo (2013) -
Tesis Doctoral
Non-canonical DNA structures in Double Strand Break repair
Camarillo Daza, María Rosa (2023-05-22)DNA double-strand breaks (DSBs) pose a serious threat to genome stability, so their proper repair is crucial for cell ...
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Tesis Doctoral
Regulación de la reparación de los cortes de doble cadena en el ADN: papel de la nedilación de proteínas
Fernández Ávila, María Jesús (2016-07-14)Las roturas de doble cadena del ADN son las lesiones más citotóxicas que pueden ocurrir en el ADN. Pueden ser reparadas ...
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Artículo
Sem1 is a functional component of the nuclear pore complex–associated messenger RNA export machinery
Boulos Faza, Marius; Kemmler, Stefan; Jimeno González, Sonia; González Aguilera, Cristina; Aguilera López, Andrés; Hurt, E (Rockefeller University Press, 2009)The evolutionarily conserved protein Sem1/Dss1 is a subunit of the regulatory particle (RP) of the proteasome, and, in ...
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Artículo
The effect of atypical nucleic acids structures in DNA double strand break repair: a tale of R-loops and G-quadruplexes
Camarillo Daza, María Rosa; Jimeno González, Sonia; Huertas Sánchez, Pablo (Frontiers Media S.A., 2021)The fine tuning of the DNA double strand break repair pathway choice relies on different regulatory layers that respond ...
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Artículo
The Emerging Role of RNA Modifications in DNA Double-Strand Break Repair
Jimeno González, Sonia; Romero Balestra, Fernando; Huertas Sánchez, Pablo (Frontiers Media S.A., 2021)The correct repair of DNA double-strand breaks is essential for maintaining the stability of the genome, thus ensuring the ...
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Artículo
The Helicase PIF1 Facilitates Resection over Sequences Prone to Forming G4 Structures
Jimeno González, Sonia; Camarillo Daza, María Rosa; Mejías Navarro, Fernando; Fernández Ávila, Mª Jesús; Soria Bretones, Isabel; Prados Carvajal, Rosario; Huertas Sánchez, Pablo (Elsevier, 2018)DNA breaks are complex lesions that can be repaired either by non-homologous end joining (NHEJ) or by homologous recombination ...
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Artículo
The THO complex as a key mRNP biogenesis factor in development and cell differentiation
Jimeno González, Sonia; Aguilera López, Andrés (BioMed Central, 2010)The THO complex is a key component in the co-transcriptional formation of messenger ribonucleoparticles that are competent ...
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Artículo
Tho1, a novel hnRNP, and Sub2 provide alternative pathways for mRNP biogenesis in yeast THO mutants
Jimeno González, Sonia; Luna Varo, Rosa María; García Rubio, María Luisa; Aguilera López, Andrés (American Society for Microbiology, 2006)THO is a protein complex that functions in cotranscriptional mRNP formation. Yeast THO1 and SUB2 (Saccharomyces cerevisiae) ...