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Listar por autor "Jiménez Cortegana, Carlos"
Mostrando ítems 1-20 de 25
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Artículo
Cancer nano-immunotherapy: the novel and promising weapon to fight cancer
García-Domínguez, Daniel J.; López Enriquez, Soledad; Alba Jiménez, Gonzalo; Garnacho Montero, Carmen; Jiménez Cortegana, Carlos; Flores-Campos, Rocío; Cruz Merino, Luis de la; Hajji, Nabil; Sánchez Margalet, Víctor; Hontecillas-Prieto, Lourdes (Mdpi Ag, 2024)Cancer is a complex disease that, despite advances in treatment and the greater understanding of the tumor biology until ...
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Circulating immune biomarkers in peripheral blood correlate with clinical outcomes in advanced breast cancer
Palazón Carrión, Natalia; Jiménez Cortegana, Carlos; Sánchez-León, M. Luisa; Henao Carrasco, Fernando Manuel; Nogales-Fernández, Esteban; Chiesa, Massimo; Caballero, Rosalía; Rojo, Federico; Nieto García, María Adoración; Sánchez Margalet, Víctor; Cruz Merino, Luis de la (Nature publishing group, 2021)Identifcation of the diferent elements intervening at the tumor microenvironment seems key to explain clinical evolution ...
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Artículo
Circulating immune biomarkers in peripheral blood correlate with clinical outcomes in advanced breast cancer
Palazón Carrión, Natalia; Jiménez Cortegana, Carlos; Sánchez León, María Luisa; Nieto García, María Adoración; Sánchez Margalet, Víctor; Cruz Merino, Luis de la (Nature Publishing Group, 2021-07-13)Identification of the different elements intervening at the tumor microenvironment seems key to explain clinical evolution ...
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Circulating myeloid-derived suppressor cells and regulatory T cells as immunological biomarkers in refractory/relapsed diffuse large B-cell lymphoma: translational results from the R2-GDP-GOTEL trial
Jiménez Cortegana, Carlos; Palazón Carrión, Natalia; Martín García-Sancho, Alejandro; Nogales-Fernández, Esteban; Carnicero-González, Fernando; Ríos Herranz, Eduardo; Sánchez Margalet, Víctor; Cruz Merino, Luis de la (BMJ, 2021)Background The search for immunological markers with ability of predicting clinical outcome is a priority in lymphomas, ...
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Circulating myeloid-derived suppressor cells may be a useful biomarker in the follow-up of unvaccinated COVID-19 patients after hospitalization
Jiménez Cortegana, Carlos; Salamanca, Elena; Palazón Carrión, Natalia; Sánchez Jiménez, Flora; Pérez Pérez, Antonio; Vilariño García, Teresa; Gutiérrez Gutiérrez, Belén; Garnacho Montero, José; Cruz Merino, Luis de la; Rodríguez-Baño, Jesús; Sánchez Margalet, Víctor (Frontiers Media S.A., 2023)SARS-CoV-2 infection is the cause of the disease named COVID-19, a major public health challenge worldwide. Differences ...
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Circulating regulatory T cells from breast cancer patients in response to neoadjuvant chemotherapy
Sánchez Margalet, Víctor; Barco Sánchez, Antonio; Vilariño García, Teresa; Jiménez Cortegana, Carlos; Pérez Pérez, Antonio; Henao Carrasco, Fernando Manuel; Lobo Acosta, María Ángeles; Cruz Merino, Luis de la (Amer Publ Co, 2019)Background: Immune escape of tumor cells is a new hallmark of cancer in general, and breast cancer, in particular. ...
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Defining the Emergence of New Immunotherapy Approaches in Breast Cancer: Role of Myeloid-Derived Suppressor Cells
Sánchez León, María Luisa; Jiménez Cortegana, Carlos; Silva Romeiro, Silvia; Garnacho Montero, Carmen; Cruz Merino, Luis de la; García-Domínguez, Daniel J.; Hontecillas-Prieto, Lourdes; Sánchez Margalet, Víctor (Mdpi Ag, 2023)Breast cancer (BC) continues to be the most diagnosed tumor in women and a very heterogeneous disease both inter- and ...
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Dendritic cells: the yin and yang in disease progression
Jiménez Cortegana, Carlos; Palomares, Francisca; Alba Jiménez, Gonzalo; Santa-María Pérez, Consuelo; Cruz Merino, Luis de la; Sánchez Margalet, Víctor; López Enriquez, Soledad (Frontiers Media, 2024-01-04)Dendritic cells (DCs) are antigen presenting cells that link innate and adaptive immunity. DCs have been historically ...
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Tesis Doctoral
Estudio poblaciones celulares en pacientes con linfoma difuso de células B grandes refractarios o en recaída: papel de las células supresoras de origen mieloide en respuesta al tratamiento R2-GDP
Jiménez Cortegana, Carlos (2020-07-13)La inmunoedición, que se caracteriza por el escape que realizan las células malignas de la inmunovigilancia antitumoral, ...
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Lenalidomide plus R-GDP (R2-GDP) in Relapsed/ Refractory Diffuse Large B-Cell Lymphoma: Final Results of the R2-GDP-GOTEL Trial and Immune Biomarker Subanalysis
Palazón Carrión, Natalia; Martín García-Sancho, Alejandro; Nogales-Fernández, Esteban; Jiménez Cortegana, Carlos; Carnicero-González, Fernando; Ríos Herranz, Eduardo; Sánchez Margalet, Víctor; Rueda Domínguez, Antonio; Cruz Merino, Luis de la (AMER ASSOC CANCER RESEARCH, 2022)Purpose: New therapeutic options are needed in relapsed/refrac tory diffuse large B-cell lymphoma (R/R DLBCL). Lenalidomide ...
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Leptin, both bad and good actor in cancer
Jiménez Cortegana, Carlos; López-Saavedra, Ana; Sánchez Jiménez, Flora; Pérez Pérez, Antonio; Castiñeiras Fernández, Jesús; Virizuela-Echaburu, Juan A.; Cruz Merino, Luis de la; Sánchez Margalet, Víctor (MDPI, 2021)Leptin is an important regulator of basal metabolism and food intake, with a pivotal role in obesity. Leptin exerts many ...
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Low levels of granulocytic myeloid-derived suppressor cells may be a good marker of survival in the follow-up of patients with severe COVID-19
Jiménez Cortegana, Carlos; Sánchez Jiménez, Flora; Pérez Pérez, Antonio; Álvarez, Nerissa; Sousa, Alberto; Cantón Bulnes, María Luisa; Cruz Merino, Luis de la; Sánchez Margalet, Víctor (Frontiers Media S.A., 2022)Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a disease (coronavirus disease 2019, ...
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Lower Survival and Increased Circulating Suppressor Cells in Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma with Deficit of Vitamin D Levels Using R-GDP Plus Lenalidomide (R2-GDP): Results from the R2-GDP-GOTEL Trial
Jiménez Cortegana, Carlos; Sánchez Martínez, Pilar M.; Palazón Carrión, Natalia; Nogales Fernández, Esteban; Henao Carrasco, Fernando Manuel; García Sancho, Alejandro Martín; Rueda, Antonio; Provencio, Mariano; Cruz Merino, Luis de la; Sánchez Margalet, Víctor (MDPI, 2021-09-15)The search of prognostic factors is a priority in diffuse large B-cell lymphoma (DLBCL) due to its aggressiveness. We ...
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Artículo
Myeloid-derived suppressor cells and vaccination against pathogens
Prochetto, Estefanía; Borgna, Eliana; Jiménez Cortegana, Carlos; Sánchez Margalet, Víctor; Cabrera, Gabriel (Frontiers Media, 2022-09-29)It is widely accepted that the immune system includes molecular and cellular components that play a role in regulating and ...
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Artículo
NK cells and solid tumors therapeutic potential and persisting obstacles
Tong, Le; Jiménez Cortegana, Carlos; Tay, Apple H.M.; Wickström, Stina; Galluzzi, Lorenzo; Lundqvist, Andreas (BMC, 2022-11-01)Natural killer (NK) cells, which are innate lymphocytes endowed with potent cytotoxic activity, have recently attracted ...
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Nutrients and Dietary Approaches in Patients with Type 2 Diabetes Mellitus and Cardiovascular Disease: A Narrative Review
Jiménez Cortegana, Carlos; Iglesias, Pedro; Ribalta, Josep; Vilariño García, Teresa; Montañez, Laura; Arrieta, Francisco; Durán García, Santiago; Sánchez Margalet, Víctor (MDPI, 2021-11-19)Cardiovascular disease (CVD) is the most common cause of morbidity and mortality in developed countries. The prevalence ...
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Obesity and Risk for Lymphoma: Possible Role of Leptin
Jiménez Cortegana, Carlos; Hontecillas Prieto, Lourdes; García-Domínguez, Daniel J.; Zapata, Fernando; Palazón Carrión, Natalia; Sánchez León, María Luisa; Tami, Malika; Pérez Pérez, Antonio; Sánchez Jiménez, Flora; Vilariño García, Teresa; Cruz Merino, Luis de la; Sánchez Margalet, Víctor (MDPI, 2022-12-08)Obesity, which is considered a pandemic due to its high prevalence, is a risk factor for many types of cancers, including ...
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Obesity as a Risk Factor for Dementia and Alzheimer’s Disease: The Role of Leptin
Flores Cordero, Juan Antonio; Pérez Pérez, Antonio; Jiménez Cortegana, Carlos; Alba Jiménez, Gonzalo; Flores-Barragán, Alfonso; Sánchez Margalet, Víctor (MDPI AG, 2022)Obesity is a growing worldwide health problem, affecting many people due to excessive saturated fat consumption, lack of ...
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Artículo
Pembrolizumab in combination with gemcitabine for patients with HER2-negative advanced breast cancer: GEICAM/2015–04 (PANGEA-Breast) study
Cruz Merino, Luis de la; Gion, M.; Cruz, J.; Alonso-Romero, J. L.; Quiroga, V.; Moreno, F.; Jiménez Cortegana, Carlos; Sánchez Margalet, Víctor; Rojo, F. (BMC, 2023)Background: We evaluated a new chemoimmunotherapy combination based on the anti-PD1 monoclonal antibody pembrolizumab and ...
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Artículo
Pembrolizumab Plus Gemcitabine in the Subset of Triple-Negative Advanced Breast Cancer Patients in the GEICAM/2015-04 (PANGEA-Breast) Study
Cruz Merino, Luis de la; Gion, María; Cruz Jurado, Josefina; Quiroga, Vanesa; Andrés, Raquel; Moreno, Fernando; Jiménez Cortegana, Carlos; Sánchez Margalet, Víctor; Rojo, Federico (MDPI, 2021-10-29)The PANGEA-Breast trial evaluated a new chemo-immunotherapeutic combination that would synergistically induce long-term ...