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Listar por autor "García Calderón, Clara Beatriz"
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Tesis Doctoral
Contribución del regulon Rcs a la virulencia de Salmonella análisis genético y molecular
García Calderón, Clara Beatriz (2008)En el momento de iniciar esta tesis, trabajos recientes de nuestro laboratorio en colaboración con el Dr. García del ...
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Artículo
FANCD2 maintains replication fork stability during misincorporation of the DNA demethylation products 5-hydroxymethyl-2’-deoxycytidine and 5-hydroxymethyl-2’-deoxyuridine
Peña Gómez, Mª José; Moreno Gordillo, Paula; Narmonté, Milda; García Calderón, Clara Beatriz; Ruksenaité, Audronė; Klimašauskas, Saulius; Valle Rosado, Iván (Springer Nature, 2022)Fanconi anemia (FA) is a rare hereditary disorder caused by mutations in any one of the FANC genes. FA cells are mainly ...
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Artículo
Fluorescent calixarene-schiff as a nanovehicle with biomedical purposes
Lebrón Romero, José Antonio; Moyá Morán, María Luisa; López López, Manuel; Deasy, M.; Muñoz Wic, Ana; García Calderón, Clara Beatriz; Valle Rosado, Iván; Bernal Pérez, Eva; Ostos Marcos, Francisco José; López-Cornejo, María del Pilar (Multidisciplinary Digital Publishing Institute (MDPI), 2022-07-14)Gene therapy is a technique that is currently under expansion and development. Recent advances in genetic medicine have ...
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Artículo
Metallo-Liposomes of Ruthenium Used as Promising Vectors of Genetic Material
Lebrón Romero, José Antonio; Ostos Marcos, Francisco José; López López, Manuel; Moyá Morán, María Luisa; Sales, Carlos; García, Encarnación; García Calderón, Clara Beatriz; García Calderón, Margarita; Peña Gómez, Mª José; Valle Rosado, Iván; Romero Balestra, Fernando; Huertas Sánchez, Pablo; López-Cornejo, María del Pilar (MDPI, 2020)Gene therapy is a therapeutic process consisting of the transport of genetic material into cells. The design and preparation ...
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Artículo
Monitoring of kinetics and exhaustion markers of circulating CAR-T cells as early predictive factors in patients with B-cell malignancies
García Calderón, Clara Beatriz; Sierro-Martínez, Belén; García-Guerrero, Estefanía; Sanoja-Flores, Luzalba; Muñoz-García, Raquel; Ruiz-Maldonado, Victoria; Carrasco-Brocal, Inmaculada; Pérez Simón, José Antonio; Caballero Velázquez, Teresa (Frontiers Media, 2023)Purpose: CAR-T cell therapy has proven to be a disruptive treatment in the hematology field, however, less than 50% of ...
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Artículo
Multivalent Calixarene-Based Liposomes as Platforms for Gene and Drug Delivery
Lebrón Romero, José Antonio; López López, Manuel; García Calderón, Clara Beatriz; Valle Rosado, Iván; Romero Balestra, Fernando; Huertas Sánchez, Pablo; Rodik, Roman V; Kalchenko, Vitaly I.; Bernal Pérez, Eva; Moyá Morán, María Luisa; López-Cornejo, María del Pilar; Ostos Marcos, Francisco José (MDPI, 2021-08)The formation of calixarene-based liposomes was investigated, and the characterization of these nanostructures was carried ...
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Artículo
Rcs and PhoPQ regulatory overlap in the control of Salmonella enterica virulence
Ramos Morales, Francisco; García Calderón, Clara Beatriz; Casadesús Pursals, Josep (Journal of Bacteriology, 2007)Genetic screens based on the use of MudJ-generated lac fusions permitted the identification of novel genes regulated by ...
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Artículo
Regulation of igaA and the rcs system by the mvia response regulator in salmonella enterica
Ramos Morales, Francisco; García Calderón, Clara Beatriz; Casadesús Pursals, Josep (American Society for Microbiology, 2009)IgaA is a membrane protein that prevents overactivation of the Rcs regulatory system in enteric bacteria. Here we provide ...
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Artículo
Targeting Hedgehog Signaling with Glasdegib in Patients with Refractory Sclerotic Chronic GVHD: A Report of Two Phase I/II Trials
Rodríguez-Arbolí, Eduardo; Lee, Catherine J; Caballero Velázquez, Teresa; Martinez, Carmen; García Calderón, Clara Beatriz; Jiménez León, María Reyes; Bermudez-Rodriguez, Maria Aranzazu; Pérez Simón, José Antonio (American Association for Cancer Research, 2023)Purpose: Sclerotic chronic GVHD (scGVHD) is characterized by progressive skin fibrosis and frequent refractoriness to ...