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Listar por autor "Cowburn, Andrew S."
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Artículo
Endothelial cell regulation of systemic haemodynamics and metabolism acts through the HIF transcription factors
Lambden, Simon; Cowburn, Andrew S.; Macías, David; Garrud, Tessa A. C.; Krause, Bernardo J.; Giussani, Dino A.; Summers, Charlotte; Johnson, Randall S. (SpringerOpen, 2021-06-11)Background The vascular endothelium has important endocrine and paracrine roles, particularly in the regulation of vascular ...
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Artículo
HIF-2a is essential for carotid body development and function
Macías, David; Cowburn, Andrew S.; Torres Torrelo, Hortensia; Ortega Sáenz, Patricia; López Barneo, José; Johnson, Randall S (eLife Sciences Publications, 2018-04-19)Mammalian adaptation to oxygen flux occurs at many levels, from shifts in cellular metabolism to physiological adaptations ...
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Artículo
Targeting HIF2α-ARNT hetero-dimerisation as a novel therapeutic strategy for pulmonary arterial hypertension
Macías, David; Moore, Stephen; Crosby, Alexi; Southwood, Mark; Du, Xinlin; Tan, Huiling; Cowburn, Andrew S. (European Respiratory Society, 2021-03-04)Pulmonary arterial hypertension (PAH) is a destructive disease of the pulmonary vasculature often leading to right heart ...