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Listar por autor "Cotán, David"
Mostrando ítems 1-7 de 7
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Artículo
Amitriptyline induces mitophagy that precedes apoptosis in human HepG2 cells
Villanueva-Paz, Marina; Cordero, Mario D.; Pavón, Ana Delgado; Castejón Vega, Beatriz; Cotán, David; De la Mata, Mario; Oropesa-Ávila, Manuel; Alcocer-Gómez, Elísabet; Muntané Relat, Jordi; Miguel Rodríguez, Manuel de; Sánchez-Alcázar, José Antonio (2016-08-07)Systemic treatments for hepatocellular carcinoma (HCC) have been largely unsuccessful. This study investigated the ...
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Apoptotic microtubules delimit an active caspase free area in the cellular cortex during the execution phase of apoptosis.
Mata Fernández, Mario de la; Sánchez Alcázar, José Antonio; Miguel Rodríguez, Manuel de; Cordero Morales, Mario David; Zaderenko Partida, Ana-Paula; Ybot González, Patricia; Cotán, David; Oropesa Ávila, Manuel; Garrido Maraver, Juan (2013) -
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Autophagic dysfunction in patients with Papillon-Lefèvre syndrome is restored by recombinant cathepsin C treatment
Bullon, Pedro; Castejón Vega, Beatriz; Román-Malo, Lourdes; Jimenez-Guerrero, María Paz; Cotán, David; Cordero, Mario D. (2018)Background: Cathepsin C (CatC) is a lysosomal enzyme involved in activation of serine proteases from immune and ...
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Mitochondrial dysfunction and mitophagy activation in blood mononuclear cells of fibromyalgia patients: implications in the pathogenesis of the disease
Cordero, Mario D.; Miguel Rodríguez, Manuel de; Moreno-Fernández, Ana María; Carmona López, María Inés; Garrido Maraver, Juan; Cotán, David; Gómez Izquierdo, Lourdes; Bonal Pitz, Pedro Pablo; Campa Valera, Francisco; Bullon, Pedro; Navas, Plácido; Sánchez Alcázar, José Antonio (BioMed Central, 2010)Introduction: Fibromyalgia is a chronic pain syndrome with unknown etiology. Recent studies have shown some evidence ...
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Mitochondrial imbalance as a new approach to the study of fibromyalgia
Martínez-Lara, Antonio; Moreno-Fernández, Ana María; Jiménez-Guerrero, Maripaz; Díaz-López, Claudia; Miguel Rodríguez, Manuel de; Cotán, David; Sánchez-Alcázar, José Antonio (Dovepress, 2020)Background: Fibromyalgia (FM) is a common chronic pain disease, whose pathogenic mechanism still remains elusive. Oxidative ...
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Pantothenate Rescues Iron Accumulation in Pantothenate Kinase-Associated Neurodegeneration Depending on the Type of Mutation
Álvarez Córdoba, Mónica; Fernández Khoury, Aida; Villanueva Paz, Marina; Gómez Navarro, Carmen; Villalón García, Irene; Suárez Rivero, Juan M.; Povea Cabello, Suleva; Mata, Mario de la; Cotán, David; Talaverón Rey, Marta; Pérez Pulido, Antonio J.; Salas, Joaquín J.; Pérez Villegas, Eva Mª; Díaz Quintana, Antonio Jesús; Armengol, José A.; Sánchez Alcázar, José A. (Springer Nature, 2019)Neurodegeneration with brain iron accumulation (NBIA) is a group of inherited neurologic disorders in which iron accumulates ...
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Pharmacological Chaperones and Coenzyme Q10 Treatment Improves Mutant β-Glucocerebrosidase Activity and Mitochondrial Function in Neuronopathic Forms of Gaucher Disease
Mata, Mario de la; Cotán, David; Oropesa Ávila, Manuel; Garrido Maraver, Juan; Cordero Morales, Mario David; Ortiz Mellet, Carmen; Ybot González, Patricia; García Fernández, José Manuel (Nature Publishing Group, 2015)Gaucher disease (GD) is caused by mutations in the GBA1 gene, which encodes lysosomal β-glucocerebrosidase. Homozygosity ...