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Browsing by Author "Cano, Josefina"
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Article
Analysis of ceftriaxone and ceftazidime distribution in cerebrospinal fluid of and cerebral extracellular space in awake rats by in vivo microdialysis
Granero, Luis; Santiago Pavón, Martiniano; Cano, Josefina; Machado Quintana, Alberto; Peris, José Esteban (American Society for Microbiology, 1995)In vivo microdialysis was used to estimate the extracellular concentrations of ceftazidime and ceftriaxone, two expanded-spectrum ...
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Article
Apoptosis-inducing factor mediates dopaminergic cell death in response to LPS-induced inflammatory stimulus: Evidence in Parkinson's disease patients
Burguillos García, Miguel Ángel; Hajji, Nabil; Englund, Elisabet; Persson, Annette; Cenci, Maria Angela; Machado, Alberto; Cano, Josefina; Joseph, Bertrand; Venero Recio, José Luis (Elsevier, 2011-01)We show that intranigral lipopolysaccharide (LPS) injection, which provokes specific degeneration of DA neurons, induced ...
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Article
Caspase signalling controls microglia activation and neurotoxicity
Burguillos García, Miguel Ángel; Deierborg, Tomas; Kavanagh, Edel T.; Persson, Annette; Hajji, Nabil; García Quintanilla, Alberto; Cano, Josefina; Brundin, Patrik; Englund, Elisabet; Venero Recio, José Luis; Joseph, Bertrand (Springer Nature, 2011-04-11)Activation of microglia and inflammation-mediated neurotoxicity are suggested to play a decisive role in the pathogenesis ...
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Inflammatory animal model for parkinson’s disease: the intranigral injection of LPS induced the inflammatory process along with the selective degeneration of nigrostriatal dopaminergic neurons
Machado Quintana, Alberto; Herrera Carmona, Antonio José; Venero Recio, José Luis; Santiago Pavón, Martiniano; Martínez de Pablos, Rocío; Espinosa Oliva, Ana María; Argüelles Castilla, Sandro; Sarmiento Soto, Manuel; Delgado Cortés, M.J.; Mauriño, R.; Cano, Josefina (A. Conti and A. Lewen, 2011)We have developed an animal model of degeneration of the nigrostriatal dopaminergic neurons, the neuronal system involved in ...
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Article
Mitochondrial toxins and neurodegenerative diseases
Ayala Gómez, Antonio; Venero Recio, José Luis; Cano, Josefina; Machado, Alberto (IMR Press, 2007)The selective loss of a particular subset of neurons is a common feature of neurodegenerative disorders. A failure in ...
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Article
Peripheral inflammation increases the damage in animal models of nigrostriatal dopaminergic neurodegeneration: Possible implication in parkinson's disease incidence
Machado Quintana, Alberto; Herrera Carmona, Antonio José; Venero Recio, José Luis; Santiago Pavón, Martiniano; Martínez de Pablos, Rocío; Villarán, Ruth; Espinosa Oliva, Ana María; Argüelles Castilla, Sandro; Sarmiento Soto, Manuel; Delgado Cortés, M.J.; Mauricio, R.; Cano, Josefina (Hindawi Publishing Corporation, 2011)Inflammatory processes described in Parkinson’s disease (PD) and its animal models appear to be important in the progression of ...