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Listar por autor "Burguillos García, Miguel Ángel"
Mostrando ítems 1-20 de 26
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Tesis Doctoral
A dual tool. The role of the ripoptosome in phagocytic cell activation and differentiation
Oliva Martín, María José (2015-10-19)El término ripoptosoma hace referencia a la plataforma molecular que contiene, entre otras, dos proteínas implicadas en ...
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Artículo
Apoptosis-inducing factor mediates dopaminergic cell death in response to LPS-induced inflammatory stimulus: Evidence in Parkinson's disease patients
Burguillos García, Miguel Ángel; Hajji, Nabil; Englund, Elisabet; Persson, Annette; Cenci, Maria Angela; Machado, Alberto; Cano, Josefina; Joseph, Bertrand; Venero Recio, José Luis (Elsevier, 2011-01)We show that intranigral lipopolysaccharide (LPS) injection, which provokes specific degeneration of DA neurons, induced ...
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Tesis Doctoral
Biochemical and molecular bases of the cell death in the neuroinflammatory of Parkinson's disease induced by LPS
Burguillos García, Miguel Ángel (2009) -
Artículo
Brainiac Caspases: Beyond the Wall of Apoptosis
Espinosa Oliva, Ana María; García Revilla, Juan; Alonso Bellido, Isabel María; Burguillos García, Miguel Ángel (Frontiers Media, 2019)For the last two decades, caspases, a family of cysteine-aspartic proteases, have evolved from being considered solely as ...
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Artículo
Caspase signalling controls microglia activation and neurotoxicity
Burguillos García, Miguel Ángel; Deierborg, Tomas; Kavanagh, Edel T.; Persson, Annette; Hajji, Nabil; García Quintanilla, Alberto; Cano, Josefina; Brundin, Patrik; Englund, Elisabet; Venero Recio, José Luis; Joseph, Bertrand (Springer Nature, 2011-04-11)Activation of microglia and inflammation-mediated neurotoxicity are suggested to play a decisive role in the pathogenesis ...
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Artículo
Cell Death Related Proteins Beyond Apoptosis in the CNS
Bahatyrevich Kharitonik, Bazhena; Medina Guzmán, Rafael; Flores Cortés, Alicia; García Cruzado, Marta; Kavanagh, Edel T.; Burguillos García, Miguel Ángel (Frontiers Media S.A., 2022)Cell death related (CDR) proteins are a diverse group of proteins whose original function was ascribed to apoptotic cell ...
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Trabajo Fin de Grado
COVID-19: manifestaciones neurológicas asociadas y efectos sobre la neurodegeneración
Morillo García, Claudia (2021)El SARS-CoV2 (coronavirus de tipo 2 causante del síndrome respiratorio agudo severo) responsable de la enfermedad COVID-19, ...
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Artículo
Deletion of caspase-8 in mouse myeloid cells blocks microglia pro-inflammatory activation and confers protection in MPTP neurodegeneration model
Kavanagh, Edel T.; Burguillos García, Miguel Ángel; Carrillo Jiménez, Alejandro; Oliva Martín, María José; Santiago Pavón, Martiniano; Rodhe, Johanna; Joseph, Bertrand; Venero Recio, José Luis (Impact Journals, LLC, 2015)Increasing evidence involves sustained pro-inflammatory microglia activation in the pathogenesis of different neurodegenerative ...
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Artículo
Docosahexaenoic acid reduces microglia phagocytic activity via miR-124 and induces neuroprotection in rodent models of spinal cord contusion injury
Burguillos García, Miguel Ángel; Kei Yip, Ping; Bowes, Amy L.; Hall, Jodie C.E.; Richard Ip, T.H.; Baskerville, Tracey; Liu, Zhuo Hao; Michael-Titus, Adina T. (Oxford University Press, 2019-07-15)Microglia are activated after spinal cord injury (SCI), but their phagocytic mechanisms and link to neuroprotection remain ...
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Artículo
Effective Knockdown of Gene Expression in Primary Microglia With siRNA and Magnetic Nanoparticles Without Cell Death or Inflammation
Carrillo Jiménez, Alejandro; Puigdellívol, Mar; Vilalta, Anna; Venero Recio, José Luis; Brown, Charles Guy; Burguillos García, Miguel Ángel (Frontiers Media, 2018)Microglia, the resident immune cells of the brain, have multiple functions in physiological and pathological conditions, ...
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Trabajo Fin de Grado
Estudio de la evolución histórica de distintos tratamientos en pacientes con patologías neurodegenerativas
Belloso Hernández, Felicitas (2022-11)Las enfermedades neurodegenerativas están compuestas por patologías que provocan la destrucción de las neuronas en el ...
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Artículo
Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration
Kei Yip, Ping; Carrillo Jiménez, Alejandro; King, Paul; Vilalta, Anna; Venero Recio, José Luis; Burguillos García, Miguel Ángel (Nature, 2017)Traumatic brain injury (TBI) is currently a major cause of morbidity and poor quality of life in Western society, with an ...
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Artículo
Galectin-3, a rising star in modulating microglia activation under conditions of neurodegeneration
García Revilla, Juan; Boza Serrano, Antonio; Espinosa Oliva, Ana María; Sarmiento Soto, Manuel; Deierborg, Tomas; Ruiz Laza, Rocío; Martínez de Pablos, Rocío; Burguillos García, Miguel Ángel; Venero Recio, José Luis (Springer Nature, 2022)The advent of high-throughput single-cell transcriptomic analysis of microglia has revealed different phenotypes that are ...
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Artículo
Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype
Shen, Xianli; Burguillos García, Miguel Ángel; Osman, Ahmed Mohamed; Frijhoff, Jeroen; Carrillo Jiménez, Alejandro; Kanatani, Sachie; Augsten, Martin; Saidi, Dalel; Rodhe, Johanna; Kavanagh, Edel T.; Venero Recio, José Luis; Joseph, Bertrand (Springer Nature, 2016-10-19)Glioma cells recruit and exploit microglia (the resident immune cells of the brain) for their proliferation and invasion ...
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Artículo
Magnetofection as a new tool to study microglia biology
Venero Recio, José Luis; Burguillos García, Miguel Ángel (Medknow Publications, 2019) -
Artículo
Microglia-secreted galectin-3 acts as a toll-like receptor 4 ligand and contributes to microglial activation
Burguillos García, Miguel Ángel; Svensson, Martina; Schulte, Tim; Boza Serrano, Antonio; García Quintanilla, Alberto; Kavanagh, Edel T.; Santiago Pavón, Martiniano; Viceconte, Nikenza; Oliva Martín, María José; Osman, Ahmed Mohamed; Salomonsson, Emma; Amar, Lahouari; Persson, Annette; Blomgren, Klas; Achour, Adnane; Englund, Elisabet; Leffler, Hakon; Venero Recio, José Luis; Joseph, Bertrand; Deierborg, Tomas (2015)Inflammatory response induced by microglia plays a critical role in the demise of neuronal populations in neuroinflammatory ...
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Artículo
Microglia: Agents of the CNS Pro-Inflammatory Response
Rodríguez Gómez, José Antonio; Kavanagh, Edel T.; Engskog-Vlachos, Pinelopi; Engskog, Mikael; Herrera Carmona, Antonio José; Espinosa Oliva, Ana María; Joseph, Bertrand; Hajji, Nabil; Venero Recio, José Luis; Burguillos García, Miguel Ángel (Multidisciplinary Digital Publishing Institute (MDPI), 2020)The pro-inflammatory immune response driven by microglia is a key contributor to the pathogenesis of several neurodegenerative ...
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Artículo
Neuromelanin activates proinflammatory microglia through a caspase-8-dependent mechanism
Viceconte, Nikenza; Burguillos García, Miguel Ángel; Herrera Carmona, Antonio José; Martínez de Pablos, Rocío; Joseph, Bertrand; Venero Recio, José Luis (BioMed Central, 2015)Background We have uncovered a caspase-dependent (caspase-8/caspase-3/7) signaling governing microglia activation and ...
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Artículo
Neuroprotective effect of rice bran enzymatic extract-supplemented diets in a murine model of Parkinsońs disease
Gavilán Dorronzoro, Elena; Flores, Alicia; Castaño Navarro, Angélica; Martín Presas, Luis; Bahatyrevich Kharitonik, Bazhena; Medina Guzmán, Rafael; Parrado Rubio, Juan; Burguillos García, Miguel Ángel (Elsevier, 2024-05-03)Neurodegenerative disorders such as Parkinson's disease, present a global health concern with limited therapeutic options. ...
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Tesis Doctoral
Papel de la galectina-3 en la respuesta inmune y en la pérdida neuronal asociada a un modelo murino de daño cerebral traumático.
Carrillo Jiménez, Alejandro (2018-07-13)La lesión cerebral traumática (TBI) es actualmente una causa importante de muerte y discapacidad en la sociedad occidental, ...