Perfil del autor: Escudero Cuadrado, Luis María
Datos institucionales
Nombre | Escudero Cuadrado, Luis María |
Departamento | Biología Celular |
Área de conocimiento | Biología Celular |
Categoría profesional | Profesor Titular de Universidad |
Correo electrónico | Solicitar |
Estadísticas
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Nº publicaciones
34
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Nº visitas
5957
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Nº descargas
6600
Publicaciones |
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Tesis Doctoral
Mechanisms of epithelial packing in proliferative tissues
(2024)
Tissue morphogenesis is intimately linked with the complex changes that occur in the shape and organization of individual ... |
Artículo
Local and global changes in cell density induce reorganisation of 3D packing in a proliferating epithelium
(The Company of Biologists, 2024)
Tissue morphogenesis is intimately linked to the changes in shape and organisation of individual cells. In curved epithelia, ... |
Tesis Doctoral
Estudio de la arquitectura epitelial en 3D, su variación natural y la aparición de patrones morfológicos a nivel celular
(2023)
Una de las cuestiones más fascinantes de la Biología del desarrollo es entender cómo los tejidos y órganos adquieren su ... |
Trabajo Fin de Grado
Métodos de software libre para el análisis de imágenes biológicas
(2023)
Hoy en día, los métodos computacionales son indispensables para el análisis de imágenes biológicas. Gracias a ellos, es ... |
Artículo
Curvature in Biological Systems: Its Quantification, Emergence, and Implications across the Scales
(John Wiley and Sons Inc, 2023)
Surface curvature both emerges from, and influences the behavior of, living objects at length scales ranging from cell ... |
Artículo
CartoCell, a high-content pipeline for 3D image analysis, unveils cell morphology patterns in epithelia
(Elsevier, 2023)
Decades of research have not yet fully explained the mechanisms of epithelial self-organization and 3D packing. Single-cell ... |
Artículo
A quantitative principle to understand 3D cellular connectivity in epithelial tubes
(Cell Systems, 2022)
Apico-basal cell intercalations (scutoids) optimize packing and energy expenditure in curved epithelia. Further consequences ... |
Artículo
Mechanics and self-organization in tissue development
(Elsevier, 2021)
Self-organization is an all-important feature of living systems that provides the means to achieve specialization and ... |
Artículo
The complex three-dimensional organization of epithelial tissues
(The Company of Biologists Ltd., 2021)
Understanding the cellular organization of tissues is key to developmental biology. In order to deal with this complex ... |
Tesis Doctoral
Topological analysis of the tumour microenvironment to study Neuroblastoma
(2020)
Solid tumours and their tumour microenvironment (TME) can be considered as complex networks whose elements are in constant ... |
Tesis Doctoral
Scutoids unveil the three-dimensional packing in curved epithelia
(2020)
As animals develop, the initial simple planar epithelia of the early embryos must acquire complex three-dimensional ... |
Artículo
EpiGraph: an open-source platform to quantify epithelial organization
(Oxford University Press, 2020)
Here we present EpiGraph, an image analysis tool that quantifies epithelial organization. Our method combines computational ... |
Artículo
The topology of vitronectin: A complementary feature for neuroblastoma risk classification based on computer-aided detection
(Wiley, 2020)
Tumors are complex networks of constantly interacting elements: tumor cells, stromal cells, immune and stem cells, ... |
Ponencia
Characterising epithelial tissues using persistent entropy
(Springer, 2019)
In this paper, we apply persistent entropy, a novel topological statis- tic, for characterization of images of epithelial ... |
Artículo
Persistent entropy: a scale-invariant topological statistic for analyzing cell arrangements
(Cornell University, 2019)
In this work, we develop a method for detecting differences in the topological distribution of cells forming epithelial ... |
Tesis Doctoral |
Artículo
Nintedanib decreases muscle fibrosis and improves muscle function in a murine model of dystrophinopathy
(Nature Publishing Group, 2018)
Duchenne muscle dystrophy (DMD) is a genetic disorder characterized by progressive skeletal muscle weakness. Dystrophin ... |
Artículo
Author Correction: Scutoids are a geometrical solution to three-dimensional packing of epithelia
(Nature Research, 2018)
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Artículo
Scutoids are a geometrical solution to three-dimensional packing of epithelia
(Nature Publishing Group, 2018)
As animals develop, tissue bending contributes to shape the organs into complex three-dimensional structures. However, the ... |
Artículo
X-ray emission from a liquid curtain jet when irradiated by femtosecond laser pulses
(Springer Nature, 2017)
Laser-based sources of ionizing radiation have attracted considerable attention in the last years for their broad potential ... |
Artículo
Rules of tissue packing involving different cell types: human muscle organization
(Nature Publishing Group, 2017)
Natural packed tissues are assembled as tessellations of polygonal cells. These include skeletal muscles and epithelial ... |
Artículo
Fundamental physical cellular constraints drive self-organization of tissues
(Wiley-Blackwell, 2016)
Morphogenesis is driven by small cell shape changes that modulate tissue organization. Apical surfaces of proliferating ... |
Tesis Doctoral |
Patente. Invención
Método para obtener información útil para el diagnóstico de enfermedades neuromusculares
(Oficina Española de Patentes y Marcas (OEPM), 2014)
Método para obtener información útil para el diagnóstico de enfermedades neuromusculares. Procedimiento para obtener, a ... |
Artículo
ATM specifically mediates repair of double-strand breaks with blocked DNA ends
(Nature Publishing Group, 2014)
Ataxia telangiectasia is caused by mutations in ATM and represents a paradigm for cancer predisposition and neurodegenerative ... |
Artículo
Biotensegrity of the Extracellular Matrix: Physiology, Dynamic Mechanical Balance, and Implications in Oncology and Mechanotherapy
(Frontiers Media, 2014)
Cells have the capacity to convert mechanical stimuli into chemical changes. This process is based on the tensegrity ... |
Artículo |
Artículo
Neuromuscular disease classification system
(Spie-soc photo-optical instrumentation engineers, 2013)
Diagnosis of neuromuscular diseases is based on subjective visual assessment of biopsies from patients by the pathologist ... |
Artículo
Age-mediated transcriptomic changes in adult mouse substantia nigra
(2013)
Substantia nigra pars compacta (SNpc) is highly sensitive to normal aging and selectively degenerates in Parkinson’s disease ... |
Artículo
Topological Progression in Proliferating Epithelia Is Driven by a Unique Variation in Polygon Distribution
(Public Library of Science, 2013)
Morphogenesis is consequence of lots of small coordinated variations that occur during development. In proliferating stages, ... |
Artículo
Dual role of myosin II during Drosophila imaginal disc metamorphosis
(Nature Publishing Group, 2013)
The motor protein non-muscle myosin II is a major driver of the movements that sculpt three dimensional organs from two ... |
Artículo
Epithelial organisation revealed by a network of cellular contacts
(Nature Publishing Group, 2011)
The emergence of differences in the arrangement of cells is the first step towards the establishment of many organs. ... |
Artículo
Live imaging of Drosophila imaginal disc development
(National Academy of Sciences, 2010)
Live imaging has revolutionized the analysis of developmental biology over the last few years. The ability to track in ... |
Artículo
Mechanism of G1 arrest in the Drosophila eye imaginal disc
(2007)
Background: Most differentiating cells are arrested in G1-phase of the cell cycle and this proliferative quiescence appears ... |