NombreWellinger, Ralf Erik
DepartamentoGenética
Área de conocimientoGenética
Categoría profesionalCatedrático de Universidad
Correo electrónicoSolicitar
           
  • Nº publicaciones

    21

  • Nº visitas

    2586

  • Nº descargas

    2999


 

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A new challenge for data analytics: transposons

Wellinger, Ralf Erik; Aguilar Ruiz, Jesús Salvador (BMC, 2022)
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Manganese Stress Tolerance Depends on Yap1 and Stress-Activated MAP Kinases

García de Oya, Inés; Jiménez Gutiérrez, Elena; Gaillard, Hélène; Molina, María; Martín, Humberto; Wellinger, Ralf Erik (Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Understanding which intracellular signaling pathways are activated by manganese stress is crucial to decipher how metal ...
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Manganese is a physiologically relevant TORC1 activator in yeast and mammals

Nicastro, Raffaele; Gaillard, Hélène; Zarzuela, Laura; Peli-Gulli, Marie-Pierre; Fernández García, Elisabet; Tomé, Mercedes; García Rodríguez, Néstor; Durán, Raúl V.; De Virgilio, Claudio; Wellinger, Ralf Erik (eLife Sciences Publications, 2022)
The essential biometal manganese (Mn) serves as a cofactor for several enzymes that are crucial for the prevention of human ...
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Adaptive response of saccharomyces hosts to totiviridae L-A dsRNA viruses Is achieved through intrinsically balanced action of targeted transcription factors

Ravoitytė, Bazilė; Lukša, Juliana; Wellinger, Ralf Erik; Serva, Saulius; Servienė, Elena (Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Totiviridae L-A virus is a widespread yeast dsRNA virus. The persistence of the L-A virus alone appears to be symptomless, ...
Tesis Doctoral
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Identification and Characterization of Factors Involved in Sodium Selenite Toxicity

Heluani Gahete, Hayat; Wellinger, Ralf Erik (2021)
Selenium (Se) is an essential micronutrient in many organisms. Despite being essential for some organisms, the range between ...
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The p24 Complex Contributes to Specify Arf1 for COPI Coat Selection

Sabido Bozo, Susana; Pérez Linero, Ana María; Manzano López, Javier; Rodríguez Gallardo, Sofía; Aguilera Romero, María Auxiliadora; Cortés Gómez, Alejandro; López Martín, Sergio; Wellinger, Ralf Erik; Muñiz Guinea, Manuel (Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Golgi trafficking depends on the small GTPase Arf1 which, upon activation, drives the assembly of different coats onto ...
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Surface modulation of single-walled carbon nanotubes for selective bacterial cell agglutination

Romero Ben, Elena; Cid, Juan José; Assali, Mohyeddin; Fernández García, Elisabet; Wellinger, Ralf Erik; Khiar, Noureddine (Dove Medical Press, 2019)
Background: Bacterial resistance to antibiotics is one of the biggest challenges facing medicine today. Anti-adhesive ...
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Sumoylation of Smc5 Promotes Error-free Bypass at Damaged Replication Forks

Zapatka, Mariel; Pociño Merino, Irene; Heluani Gahete, Hayat; Bermúdez López, Marcelino; Tarrés, Marc; Ibars, Eva; Solé Soler, Roger; Gutiérrez Escribano, Pilar; Apostolova, Sonia; Casas, Celia; Aragon, Luis; Wellinger, Ralf Erik; Colomina, Neus; Torres Rosell, Jordi (Elsevier (Cell Press): OAJ, 2019)
Replication of a damaged DNA template can threaten the integrity of the genome, requiring the use of various mechanisms ...
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Repair of UV-induced DNA lesions in natural Saccharomyces cerevisiae telomeres is moderated by Sir2 and Sir3, and inhibited by yKu–Sir4 interaction

Guintini, Laetitia; Tremblay, Maxime; Toussaint, Martin; Wellinger, Ralf Erik (Oxford University Press, 2017)
Ultraviolet light (UV) causes DNA damage that is removed by nucleotide excision repair (NER). UVinduced DNA lesions must ...
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Non‐Canonical Replication Initiation: You’re Fired!

Ravoitytė, Bazilė; Wellinger, Ralf Erik (MDPI, 2017)
The division of prokaryotic and eukaryotic cells produces two cells that inherit a perfect copy of the genetic material ...
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Manganese Redistribution by Calcium-stimulated Vesicle Trafficking Bypasses the Need for P-type ATPase Function

García Rodríguez, Néstor; Manzano López, Javier; Muñoz Bravo, Miguel; Fernández García, Elisabet; Muñiz Guinea, Manuel; Wellinger, Ralf Erik (American Society for Biochemistry and Molecular Biology, 2015)
Regulation of intracellular ion homeostasis is essential for eukaryotic cell physiology. An example is provided by loss ...
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Role for RNA: DNA hybrids in origin-independent replication priming in a eukaryotic system

Stuckey, Ruth; García Rodriguez, Néstor; Aguilera López, Andrés; Wellinger, Ralf Erik (National Academy of Sciences, 2015)
DNA replication initiates at defined replication origins along eukaryotic chromosomes, ensuring complete genome duplication ...
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Yeast as a model system to study metabolic impact of selenium compounds

Herrero, Enrique; Wellinger, Ralf Erik (Shared Science Publishers, 2015)
Inorganic Se forms such as selenate or selenite (the two more abundant forms in nature) can be toxic in Saccharomyces ...
Tesis Doctoral
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Studies on the effects of persistent RNA priming on DNA replication and genomic stability.

Stuckey, Ruth; Wellinger, Ralf Erik (2014)
La replicación y la transcripción del ADN suceden al mismo tiempo y en la misma molécula de ADN de modo que su correcta ...
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Impaired manganese metabolism causes mitotic misregulation

García Rodríguez, Néstor; Díaz de la Loza, María del Carmen; Andreson, Bethany; Monje Casas, Fernando; Rothstein, Rodney; Wellinger, Ralf Erik (American Society for Biochemistry and Molecular Biology, 2012)
Manganese is an essential trace element, whose intracellular levels need to be carefully regulated. Mn2+ acts as a cofactor ...
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Zim17/Tim15 links mitochondrial iron–sulfur cluster biosynthesis to nuclear genome stability

Díaz de la Loza, María del Carmen; Gallardo Ortega, Mercedes; García Rubio, María Luisa; Izquierdo, Alicia; Herrero, Enrique; Aguilera López, Andrés; Wellinger, Ralf Erik (Oxford University Press, 2011)
Genomic instability is related to a wide-range of human diseases. Here, we show that mitochondrial iron–sulfur cluster ...
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A new connection of mRNP biogenesis and export with transcription-coupled repair

Gaillard, Hélène; Wellinger, Ralf Erik; Aguilera López, Andrés (Oxford University Press, 2007)
Although DNA repair is faster in the transcribed strand of active genes, little is known about the possible contribution ...
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Replication fork progression is impaired by transcription in hyperrecombinant yeast cells lacking a functional THO complex

Wellinger, Ralf Erik; Prado Velasco, José Félix; Aguilera López, Andrés (American Society for Microbiology, 2006)
THO/TREX is a conserved, eukaryotic protein complex operating at the interface between transcription and messenger ...
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An hpr1 point mutation that impairs transcription and mRNP biogenesis without increasing recombination

Huertas Sánchez, Pablo; García Rubio, María Luisa; Wellinger, Ralf Erik; Luna Varo, Rosa María; Aguilera López, Andrés (American Society for Microbiology, 2006)
THO/TREX, a conserved eukaryotic protein complex, is a key player at the interface between transcription and mRNP metabolism. ...
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Rad52-independent accumulation of joint circular minichromosomes during S phase in Saccharomyces cerevisiae

Wellinger, Ralf Erik; Schär, Primo; Sogo, Jose Manuel (2003)
We investigated the formation of X-shaped molecules consisting of joint circular minichromosomes (joint molecules) in ...