idUS - Author profile: García-Domínguez, Daniel J.

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Name	García-Domínguez, Daniel J.
Department	Bioquímica Médica y Biología Molecular e Inmunología
Knowledge area	Bioquímica y Biología Molecular
Professional category	Plan Propio-Acceso
E-mail	Request

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13
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991
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Publications
Article Cancer nano-immunotherapy: the novel and promising weapon to fight cancer García-Domínguez, Daniel J.; López Enriquez, Soledad; Alba Jiménez, Gonzalo; Garnacho Montero, Carmen; Jiménez Cortegana, Carlos; Flores-Campos, Rocío; Cruz Merino, Luis de la; Hajji, Nabil; Sánchez Margalet, Víctor; Hontecillas-Prieto, Lourdes (Mdpi Ag, 2024) Cancer is a complex disease that, despite advances in treatment and the greater understanding of the tumor biology until ...
Article Defining the Emergence of New Immunotherapy Approaches in Breast Cancer: Role of Myeloid-Derived Suppressor Cells Sánchez León, María Luisa; Jiménez Cortegana, Carlos; Silva Romeiro, Silvia; Garnacho Montero, Carmen; Cruz Merino, Luis de la; García-Domínguez, Daniel J.; Hontecillas-Prieto, Lourdes; Sánchez Margalet, Víctor (Mdpi Ag, 2023) Breast cancer (BC) continues to be the most diagnosed tumor in women and a very heterogeneous disease both inter- and ...
Article Obesity and Risk for Lymphoma: Possible Role of Leptin Jiménez Cortegana, Carlos; Hontecillas Prieto, Lourdes; García-Domínguez, Daniel J.; Zapata, Fernando; Palazón Carrión, Natalia; Sánchez León, María Luisa; Tami, Malika; Pérez Pérez, Antonio; Sánchez Jiménez, Flora; Vilariño García, Teresa; Cruz Merino, Luis de la; Sánchez Margalet, Víctor (MDPI, 2022) Obesity, which is considered a pandemic due to its high prevalence, is a risk factor for many types of cancers, including ...
Article Ewing Sarcoma Meets Epigenetics, Immunology and Nanomedicine: Moving Forward into Novel Therapeutic Strategies Sánchez Molina, Sara; Figuerola Bou, Elisabet; Sánchez Margalet, Víctor; Cruz Merino, Luis de la; Mora, Jaume; Álava Casado, Enrique de; García-Domínguez, Daniel J.; Hontecillas Prieto, Lourdes (MDPI, 2022) Ewing Sarcoma (EWS) is an aggressive bone and soft tissue tumor that mainly affects children, adolescents, and young adults. ...
Article Tumor Immune Microenvironment in Lymphoma: Focus on Epigenetics García-Domínguez, Daniel J.; Hontecillas Prieto, Lourdes; Palazón Carrión, Natalia; Jiménez Cortegana, Carlos; Sánchez Margalet, Víctor; Cruz Merino, Luis de la (MDPI, 2022) Lymphoma is a neoplasm arising from B or T lymphocytes or natural killer cells characterized by clonal lymphoproliferation. ...
Article Selective histone methyltransferase G9a inhibition reduces metastatic development of Ewing sarcoma through the epigenetic regulation of NEU1 García-Domínguez, Daniel J.; Hajji, Nabil; López Alemany, Roser; Sánchez Molina, Sara; Figuerola Bou, Elisabet; Morón Civanto, Francisco Jesús; Álava Casado, Enrique de; Hontecillas Prieto, Lourdes (Nature Publishing Group, 2022) Ewing sarcoma (EWS) is an aggressive bone and soft tissue tumor with high susceptibility to metastasize. The underlying ...
Article The bitter side of epigenetics: variability and resistance to chemotherapy Hajji, Nabil; García-Domínguez, Daniel J.; Hontecillas Prieto, Lourdes; O'Neill, Kevin; Álava Casado, Enrique de; Syed, Nelofer (Future Medicine, 2021) One of the major obstacles to the development of effective new cancer treatments and the main factor for the increasing ...
Article Selective inhibition of HDAC6 regulates expression of the oncogenic driver EWSR1-FLI1 through the EWSR1 promoter in Ewing sarcoma García-Domínguez, Daniel J.; Hajji, Nabil; Sánchez Molina, Sara; Figuerola Bou, Elisabet; Martínez de Pablos, Rocío; Espinosa Oliva, Ana María; Flores Campos, Rocío; Robles Frías, María José; Álava Casado, Enrique de; Hontecillas Prieto, Lourdes (Springer Nature, 2021) Ewing sarcoma (EWS) is an aggressive bone and soft tissue tumor of children and young adults in which the principal driver ...
Article An inducible ectopic expression system of EWSR1-FLI1 as a tool for understanding Ewing sarcoma oncogénesis García-Domínguez, Daniel J.; Hontecillas-Prieto, Lourdes; Andrés León, Eduardo; Sánchez-Molina, Sara; Rodríguez-Núñez, Pablo; Morón, Francisco J.; Hajji, Nabil; Mackintosh, Carlos; Álava Casado, Enrique de (Public Library of Science, 2020) The presence of the chimeric EWSR1-FLI1 oncoprotein is the main and initiating event defining Ewing sarcoma (ES). The ...
Article Synergistic Enhancement of Cancer Therapy Using HDAC Inhibitors: Opportunity for Clinical Trials Hontecillas Prieto, Lourdes; Flores Campos, Rocío; Silver, Andrew; Álava Casado, Enrique de; Hajji, Nabil; García-Domínguez, Daniel J. (Frontiers Media S.A., 2020) Chemotherapy is one of the most established and effective treatments for almost all types of cancer. However, the elevated ...
PhD Thesis Estudio de los coactivadores transcripcionales TAZ y YAP1 en el sarcoma de Ewing: Implicación en la progresión tumoral e interacción funcional con la proteína de fusión EWS-FLI1 Rodríguez Núñez, Pablo; Álava Casado, Enrique de; Díaz Martín, Juan; García-Domínguez, Daniel J. (2019) La presente tesis doctoral aborda, por primera vez, el papel funcional de los dos efectores finales de la vía Hippo, TAZ ...
Article Multidrug resistance transporter profile reveals MDR3 as a marker for stratification of blastemal Wilms tumour patients Hontecillas Prieto, Lourdes; García-Domínguez, Daniel J.; Pascual Vaca, Diego; García Mejías, Rosa; Marcilla, David; Ramírez Villar, Gema; Álava Casado, Enrique de (Impact Journals, 2017) Wilms tumour (WT) is the most common renal tumour in children. Most WT patients respond to chemotherapy, but subsets of ...
Article HMGA2 overexpression predicts relapse susceptibility of blastemal Wilms tumor patients Hontecillas Prieto, Lourdes; García-Domínguez, Daniel J.; García Mejías, Rosa; Ramírez Villar, Gema; Sáez, Carmen; Álava Casado, Enrique de (Impact Journals, 2017) Wilms tumor (WT) is an embryonal malignant neoplasm of the kidney that accounts for 6–7% of all childhood cancers. WT seems ...