Author profile: Lepe Jiménez, José Antonio
Institutional data
Name | Lepe Jiménez, José Antonio |
Department | Microbiología |
Knowledge area | Microbiología |
Professional category | Profesor Asociado CIS |
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No. publications
35
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3206
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3007
Publications |
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Article
Antimicrobial Stewardship in the Emergency Department Observation Unit: Definition of a New Indicator and Evaluation of Antimicrobial Use and Clinical Outcomes
(MDPI, 2024)
We aimed to define a novel indicator for monitoring antimicrobial use specifically in the Emergency Department Observation ... |
Article
Volatile Biomarkers of Gram-positive Bacteria of Clinical Relevance as a Tool for Infection Diagnosis
(Sociedad Española de Microbiologia, 2024)
Aim: Volatile organic compounds (VOCs) are being studied as potential biomarkers in many infections. Therefore, this study ... |
Article
Volatile biomarkers of Gram‑positive bacteria of clinical relevance as a tool for infection diagnosis
(Springer, 2024)
Aim: Volatile organic compounds (VOCs) are being studied as potential biomarkers in many infections. Therefore, this study ... |
Article
Epidemiology and risk factors of mycotic aneurysm in patients with infective endocarditis and the impact of its rupture in outcomes. Analysis of a national prospective cohort
(Oxford Univ Press, 2024)
Background. Several aspects of the occurrence and management of mycotic aneurysm (MA) in patients with infective endocarditis ... |
PhD Thesis
Escherichia coli infection: mechanisms and rapid detection of resistance to the association of ß-lactams with ß-lactamase inhibitors, and impact of the Sars-Cov-2 pandemic on the morbidity and mortality of intra-abdominal infection
(2023)
Infections by Escherichia coli in human beings produce a significant disease burden, with important morbidity and mortality, ... |
Article
Rapid Detection of Piperacillin-Tazobactam Resistance in Klebsiella pneumoniae and Escherichia coli
(American Society for Microbiology, 2023)
Rapid determination of susceptibility to piperacillin-tazobactam (TZP) is very important since the development of antibiotic ... |
Article
In vitro and in vivo virulence study of Listeria monocytogenes isolated from the Andalusian outbreak in 2019
(MDPI, 2023)
In 2019, the biggest listeriosis outbreak by Listeria monocytogenes (Lm) in the South of Spain was reported, resulting in ... |
Article
BIChromET: A Chromogenic Culture Medium for Detection of Piperacillin/Tazobactam and Cefepime Resistance in Pseudomonas aeruginosa
(MDPI, 2023)
Objectives: The BIChromET selective medium for detecting piperacillin-tazobactam (TZP) and cefepime (FEP) resistant ... |
Article
Detection of high level of co-infection and the emergence of novel SARS CoV-2 delta-omicron and omicron-omicron recombinants in the epidemiological surveillance of Andalusia
(MDPI, 2023)
Recombination is an evolutionary strategy to quickly acquire new viral properties inherited from the parental lineages. ... |
Article |
Article
Role of blaTEM and OmpC in the piperacillin-tazobactam resistance evolution by E. coli in patients with complicated intra-abdominal infection
(Elsevier, 2023)
Piperacillin-tazobactam resistance (P/T-R) is increasingly reported among Escherichia coli isolates. Although in vitro ... |
Article
Study protocol for a randomized clinical trial to assess 7 versus 14-days of treatment for Pseudomonas aeruginosa bloodstream infections (SHORTEN-2 trial)
(2022)
Background Research priorities in Antimicrobial Stewardship (AMS) have rapidly evolved in the last decade. The need for a ... |
Article
FlowUTI An interactive web-application for optimizing the use of flow cytometry as a screening tool in urinary tract infections
(Public Library of Science, 2022)
Due to the high prevalence of patients attending with urinary tract infection (UTI) symptoms, the use of flow-cytometry ... |
Article
MDR Shigella sonnei in Spain: an ever-evolving emerging threat?
(Oxford University Press, 2022)
Background Seven CTX-M-27-producing Shigella sonnei strains were isolated at the University Hospital Virgen del Rocío ... |
Article
Outpatient Parenteral Antibiotic Treatment vs Hospitalization for Infective Endocarditis: Validation of the OPAT-GAMES Criteria
(OXFORD UNIV PRESS, 2022)
Background. Outpatient parenteral antibiotic treatment (OPAT) programs are increasingly used to manage infective endocarditis ... |
Article
Assessing the Impact of SARS-CoV-2 Lineages and Mutations on Patient Survival
(MDPI, 2022)
Objectives: More than two years into the COVID-19 pandemic, SARS-CoV-2 still remains a global public health problem. ... |
Article
Prevalence and risk factors for multidrug-resistant organisms colonization in long-term care facilities around the world: a review
(MDPI, 2021)
Elderly people confined to chronic care facilities face an increased risk of acquiring infections by multidrug-resistant ... |
Article
Clinical Features and Outcomes of Streptococcus anginosus Group Infective Endocarditis: A Multicenter Matched Cohort Study
(Oxford University Press, 2021)
Background Although Streptococcus anginosus group (SAG) endocarditis is considered a severe disease associated with abscess ... |
Article
Mural Endocarditis: The GAMES Registry Series and Review of the Literature
(Springer London LTD, 2021)
Introduction Mural infective endocarditis (MIE) is a rare type of endovascular infection. We present a comprehensive series ... |
Article
Do specific antimicrobial stewardship interventions have an impact on carbapenem resistance in Gramnegative bacilli? A multicentre quasi-experimental ecological study: time-trend analysis and characterization of carbapenemases
(Oxford University Press, 2021)
Background: Carbapenem-resistant Gram-negative bacilli (CR-GNB) are among the most threatening microorganisms worldwide ... |
Article
Clinical characteristics and outcome of bacteraemia caused by Enterobacter cloacae and Klebsiella aerogenes: more similarities than differences
(Elsevier, 2021)
Objectives The genus Enterobacter is a common cause of nosocomial infections. Historically, the most frequent Enterobacter ... |
Article
Long-Term Impact of an Educational Antimicrobial Stewardship Program on Management of Patients with Hematological Diseases
(MDPI, 2021)
Antimicrobial stewardship programs (ASPs) in hematological patients are especially relevant. However, information about ... |
Article
SARS-CoV-2 viral load in nasopharyngeal swabs is not an independent predictor of unfavorable outcome
(NATURE PUBLISHING GROUP, 2021)
The aim was to assess the ability of nasopharyngeal SARS-CoV-2 viral load at frst patient’s hospital evaluation to predict ... |
Patent. Invention
Kit y método de detección rápida de bacterias resistentes a las combinaciones de antibiótico β-lactámico con un inhibidor de β- lactamasa, y de la resistencia de expectro extendido a los β-lactámicos en aislados clínicos
(Organización Mundial de la Propiedad Intelectual (OMPI), 2020)
Método de identificación de aislados bacterianos resistentes a las combinaciones de antibiótico β-lactámico con inhibidores ... |
PhD Thesis
Bacteriemias por Escherichia coli: análisis clínico-epidemiológico, de factores de patogenicidad y mecanismos de resistencia a betalactámicos/inhibidores de betalactamasas
(2020)
Las infecciones por bacterias multirresistentes son un serio problema a nivel mundial. La aparición constante de mecanismos ... |
Article
Predictors of mortality in solid organ transplant recipients with bloodstream infections due to carbapenemase-producing Enterobacterales: the impact of cytomegalovirus disease and lymphopenia
(BMC, 2020)
Treatment of carbapenemase-producing Enterobacterales bloodstream infections in solid organ transplant recipients is ... |
Article
Clinical and prognostic differences between methicillin-resistant and methicillin-susceptible Staphylococcus aureus infective endocarditis
(Biomed Central LTD, 2020)
Background: S. aureus (SA) infective endocarditis (IE) has a very high mortality, attributed to the age and comorbidities ... |
Article
Impact of the COVID-19 pandemic on antimicrobial consumption and hospital-acquired candidemia and multidrug-resistant bloodstream infections
(MDPI, 2020)
During the COVID-19 pandemic, the implementation of antimicrobial stewardship strategies has been recommended. This study ... |
Article
Impact of De-escalation on Prognosis of Patients With Bacteremia due to Enterobacteriaceae: A Post Hoc Analysis From a Multicenter Prospective Cohort
(Oxford University Press, 2019)
Background More data are needed about the safety of antibiotic de-escalation in specific clinical situations as a strategy ... |
Article
Application of BioFire FilmArray Blood Culture Identification panel for rapid identification of the causative agents of ventilator-associated pneumonia
(Elsevier, 2018)
Objective: To evaluate the ability of the BioFire FilmArray Blood Culture Identification (BCID) panel to rapidly detect ... |
PhD Thesis |
PhD Thesis |
Article
Characteristics and Outcome of Streptococcus pneumoniae Endocarditis in the XXI Century. A Systematic Review of 111 Cases (2000–2013)
(Wolters Kluwer, 2015)
Streptococcus pneumoniae is an infrequent cause of severe infectious endocarditis (IE). The aim of our study was to describe ... |
Article
Quantitative Real-Time PCR for Detection of Acinetobacter baumannii Colonization in the Hospital Environment
(American Society of Microbiology, 2012)
A real-time PCR assay was developed for detecting the presence of Acinetobacter baumannii on hospital equipment and compared ... |
Article
Positive Predictive Value of Leeds Acinetobacter Medium for Environmental Surveillance of Acinetobacter baumannii
(American Society of Microbiology, 2011)
Infections caused by Acinetobacter baumannii often occur in outbreaks during which the bacteria are spread through contact ... |