The psychosis spectrum encompasses a heterogeneous range of clinical conditions associated with abnormal brain development. ...

La esquizofrenia es una enfermedad mental grave con un 0.6-0.8% de prevalencia mundial, que se inicia durante la adolescencia ...

Emerging evidence suggests brain white matter alterations in adolescents with early-onset psychosis (EOP; age of onset <18 ...

Background. Individuals with a first episode of psychosis (FEP) show rapid weight gain during the first months of treatment, ...

Schizophrenia (SZ) is associated with an increased risk of life-long cognitive impairments, age-related chronic disease, ...

Autism spectrum disorder (ASD) is a neurodevelopmental disorder with complex clinical manifestations that arise between ...

Unravelling the complex events driving grade-specific spatial distribution of brain tumour occurrence requires rich datasets ...

Introduction Our aim was to, firstly, identify characteristics at first-episode of psychosis that are associated with later ...

Polygenic risk prediction remains an important aim of genetic association studies. Currently, the predictive power of ...

Identifying brain alterations associated with suicidal thoughts and behaviors (STBs) in young people is critical to ...

Background Cardiometabolic dysfunction is common in young people with psychosis. Recently, the Psychosis Metabolic Risk ...

Background People with psychosis are at higher risk of cardiovascular events, partly explained by a higher predisposition ...

Background Antipsychotic choice for the acute phase of a first episode of psychosis (FEP) is of the utmost importance since ...

Treatment-resistant schizophrenia (TRS) will affect about one in three patients with schizophrenia. Clozapine is the only ...

Objective Aripiprazole and risperidone are 2 of the most used second-generation antipsychotics (SGAs) worldwide. Previous ...

Reelin is an extracellular matrix glycoprotein reduced in brain regions (the prefrontal cortex and the hippocampus) of ...

Background: Few investigations have been carried out on metabolic syndrome in antipsychotic- naïve patients with ...

Schizophrenia is associated with widespread alterations in subcortical brain structure.While analytic methods have enabled ...

Introduction Health-care Workers (HCW) are facing a critical situation caused by Coronavirus Disease 2019 (COVID-19) which ...

Despite being a major cause of disability worldwide, the pathophysiology of schizophrenia and molecular basis of treatment ...

Previous research suggests an association of loneliness and social isolation (LNL-ISO) with schizophrenia. Here, we ...

The COVID-19 pandemic represents a valuable opportunity to carry out cohort studies that allow us to advance our knowledge ...

Abstract Background Sex differences in incidence and/or presentation of schizophrenia (SCZ), major depressive disorder ...

The Enhancing NeuroImaging Genetics through Meta-Analysis copy number variant (ENIGMA-CNV) and 22q11.2 Deletion Syndrome ...

In recent years, multiple studies have investigated the role of biomarkers in first-episode psychosis (FEP) to facilitate ...

Background Neurocognition impairments are critical factors in patients with major depressive disorder (MDD), bipolar ...

Importance About 20% to 30% of people with schizophrenia have psychotic symptoms that do not respond adequately to ...

Objective: Obesity and metabolic diseases such as metabolic syndrome (MetS) are more prevalent in people with type 2 ...

Risk of suicidal behaviour (SB) in schizophrenia spectrum disorders (SSD) is a major concern, particularly in early stages ...

Predicting functional outcomes after surgery and early adjuvant treatment is difficult due to the complex, extended, ...

This study aimed to compare self-reported changes on lifestyle behaviors during two phases of the COVID-19 pandemic in ...

Sex-related differences are tied into neurodevelopmental and lifespan processes, beginning early in the perinatal and ...

Delineating the association of age and cortical thickness in healthy individuals is criti-cal given the association of ...

Background: Antipsychotics modulate expression of inflammatory cytokines and inducible inflammatory enzymes. Elopiprazole ...

Background: Patients with a first episode of psychosis (FEP) are at higher risk of gaining weight and presenting ...

Age has a major effect on brain volume. However, the normative studies available are constrained by small sample sizes, ...

Background. Neuroanatomical abnormalities in first-episode psychosis (FEP) tend to be sub tle and widespread. The vast ...

Recent evidence suggests that comorbidities between neuropsychiatric conditions and metabolic syndrome may precede and ...

The burden of large and rare copy number genetic variants (CNVs) as well as certain specific CNVs increase the risk ...

In recent years, multiple studies have investigated the role of biomarkers in first-episode psychosis (FEP) to facilitate ...

Low-frequency 1q21.1 distal deletion and duplication copy number variant (CNV) carriers are predisposed to multiple neurodevelopmental ...

Few studies have used a multidimensional approach to describe lifestyle changes among undergraduate students during the ...

atients with non-affective psychosis often lead unhealthy lifestyles. We performed a systematic review and meta-analysis ...

Background: The aims of this study were to evaluate the short-term impact of 2019-nCoV outbreak on the mental/ psychological ...

Based on the discovery by the Resilience Project (Chen R. et al. Nat Biotechnol 34:531–538, 2016) of rare variants that ...

DNA methylation, which is modulated by both genetic factors and environmental exposures, may offer a unique opportunity ...

There is an increasing interest to study the interactions between atmospheric electrical parameters and living organisms ...

In the last 2 decades, several neuroimaging studies investigated brain abnormalities associated with the early stages of ...

Despite the high level of interest in the use of machine learning (ML) and neuroimaging to detect psychosis at the individual ...

Toll-like receptors (TLRs) are a pivotal component of the innate immune system that seem to have a role in the pathogenesis ...

The data presented in this paper describe supplementary material to the article entitled “Pharmacological treatment ...

Background: Schizophrenia spectrum disorders (SSD) are mental diseases caused by a combination of genetic susceptibility ...

Background and Objective Schizophrenia is a low-prevalence mental disorder with a global age-standardized prevalence of ...

While sex differences in schizophrenia have long been reported and discussed, long-term sex differences in outcomes among ...

Background: Different effectiveness profiles among antipsychotics may be a key point to optimize treatment in patients ...

The increasing availability of magnetic resonance imaging (MRI) datasets is boosting the interest in the application of ...

INTRODUCTION The cerebral cortex underlies our complex cognitive capabilities. Variations in human cortical surface area ...

This article describes data related to the research study entitled "Duration of active psychosis during early phases of ...

Carriers of large recurrent copy number variants (CNVs) have a higher risk of developing neurodevelopmental disorders. The ...

Introduction: the goal of this study was to determine the prevalence of hepatitis C virus (HCV) infection in patients ...

We organized 10Kin1day, a pop-up scientific event with the goal to bring together neuroimaging groups from around the world ...