idUS - Author profile: Muñoz Castro, Clara

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Name	Muñoz Castro, Clara
Department	Bioquímica y Biología Molecular
Knowledge area	Bioquímica y Biología Molecular
Professional category	Plan Propio-Acceso
E-mail	Request

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778
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Publications
Article Update on modifiable risk factors for Alzheimer’s disease and related dementias Jaisa Aad, Methasit; Muñoz Castro, Clara; Serrano Pozo, Alberto (Wolters Kluwer, 2024) Purpose of review. All human beings undergo a lifelong cumulative exposure to potentially preventable adverse factors such ...
Article Cyclic multiplex fluorescent immunohistochemistry and machine learning reveal distinct states of astrocytes and microglia in normal aging and Alzheimer’s disease Muñoz Castro, Clara; Noori, Ayush; Magdamo, Colin G.; Li, Zhaozhi; Marks, Jordan D.; Frosch, Matthew P.; Das, Sudeshna; Hyman, Bradley T.; Serrano Pozo, Alberto (BMC, 2022) Background Astrocytes and microglia react to Aβ plaques, neurofibrillary tangles, and neurodegeneration in the Alzheimer’s ...
Article Cytotoxicity and Effects on the Synapsis Induced by Pure Cylindrospermopsin in an E17 Embryonic Murine Primary Neuronal Culture in a Concentration-and Time-Dependent Manner Hinojosa, María Gracia; Prieto Ortega, Ana Isabel; Muñoz Castro, Clara; Sánchez Mico, María; Vitorica Ferrández, Francisco Javier; Cameán Fernández, Ana María; Jos Gallego, Ángeles Mencía (Multidisciplinary Digital Publishing Institute (MDPI), 2022) Cylindrospermopsin (CYN) is a cyanotoxin whose incidence has been increasing in the last decades. Due to its capacity to ...
Article Should we open fire on microglia? Depletion models as tools to elucidate microglial role in health and alzheimer’s disease Romero Molina, Carmen; Navarro Garrido, Victoria; Jiménez Muñoz, Sebastián; Muñoz Castro, Clara; Sánchez Mico, María; Gutiérrez, Antonia; Vitorica Ferrández, Francisco Javier; Vizuete Chacón, María Luisa (Multidisciplinary Digital Publishing Institute (MDPI), 2021) Microglia play a critical role in both homeostasis and disease, displaying a wide variety in terms of density, functional ...
Article Enhancing microtubule stabilization rescues cognitive deficits and ameliorates pathological phenotype in an amyloidogenic Alzheimer’s disease model Fernández Valenzuela, Juan José; Muñoz Castro, Clara; Jiménez Muñoz, Sebastián; Vizuete Chacón, María Luisa; Vitorica Ferrández, Francisco Javier; Gutierrez Pérez, Antonia (Nature Research, 2020) In Alzheimer’s disease (AD), and other tauopathies, microtubule destabilization compromises axonal and synaptic integrity ...
Article Distinct Microglial Responses in Two Transgenic Murine Models of TAU Pathology Romero Molina, Carmen; Navarro Garrido, Victoria; Sánchez Varo, Raquel María; Jiménez Muñoz, Sebastián; Fernández Valenzuela, Juan José; Sánchez Mico, María; Muñoz Castro, Clara; Gutiérrez Pérez, Antonia; Vitorica Ferrández, Francisco Javier; Vizuete Chacón, María Luisa (Frontiers Media Research Foundation, 2018) Microglial cells are crucial players in the pathological process of neurodegenerative diseases, such as Alzheimer’s disease ...
Article Microglia in Alzheimer’s Disease: Activated, Dysfunctional or Degenerative Navarro Garrido, Victoria; Sánchez Mejías, Elisabeth; Jiménez Muñoz, Sebastián; Muñoz Castro, Clara; Sánchez Varo, Raquel María; Dávila, José Carlos; Vizuete Chacón, María Luisa; Gutiérrez, Antonia; Vitorica Ferrández, Francisco Javier (Frontiers Media, 2018) Microglial activation has been considered a crucial player in the pathological process of multiple human neurodegenerative ...