NameGonzalo Calvo, Gonzalo de
DepartmentQuímica Orgánica
Knowledge areaQuímica Orgánica
Professional categoryProfesor Titular de Universidad
E-mailRequest
           
  • No. publications

    27

  • No. visits

    3002

  • No. downloads

    3081


 

Article
Icon

Evolution of the catalytic mechanism at the dawn of the Baeyer-Villiger monooxygenases

Yang, Guang; Pećanac, Ognjen; Wijma, Hein J.; Rozeboom, Henriëtte J.; Gonzalo Calvo, Gonzalo de; Fraaije, Marco W.; Mascotti, Maria Laura (Elsevier, 2024)
Enzymes are crucial for the emergence and sustenance of life on earth. How they became catalytically active during their ...
Article
Icon

Deep Eutectic Solvents as Catalysts in the Synthesis of Active Pharmaceutical Ingredients and Precursors

Falcini, Chiara; Gonzalo Calvo, Gonzalo de (MDPI, 2024)
Deep Eutectic Solvents (DESs) have appeared in recent years as an appealing alternative to classical organic solvents, due ...
Article
Icon

Atroposelective Synthesis of 2-(Quinolin-8-yl)benzyl Alcohols by Biocatalytic Dynamic Kinetic Resolutions

Coto Cid, Juan Manuel; Gonzalo Calvo, Gonzalo de; Carmona, José A.; Iglesias Sigüenza, Francisco Javier; Rodríguez Salamanca, Patricia; Fernández Fernández, Rosario Fátima; Hornillos, Valentín; Lassaletta, José M. (Wiley, 2023)
A highly enantioselective biocatalytic dynamic kinetic resolution (DKR) of 2-(quinoline-8-yl) 3-methylbenzaldehydes and ...
Article
Icon

Green Oxidative Catalytic Processes for the Preparation of APIs and Precursors

García Fernández, Pedro David; Coto Cid, Juan Manuel; Gonzalo Calvo, Gonzalo de (MDPI, 2023)
Asymmetric oxidation processes have constituted a valuable tool for the synthesis of active pharmaceutical ingredients ...
Article
Icon

Biocatalytic Atroposelective Synthesis of Axially Chiral N-Arylindoles via Dynamic Kinetic Resolution

Rodríguez Salamanca, Patricia; Gonzalo Calvo, Gonzalo de; Carmona, José A.; López Serrano, Joaquín; Iglesias Sigüenza, Francisco Javier; Fernández Fernández, Rosario Fátima; Lassaletta, José M.; Hornillos, Valentín (American Chemical Society, 2022)
A highly enantioselective biocatalytic dynamic kinetic resolution (DKR) of configurationally labile N-arylindole aldehydes ...
Article
Icon

Application of Biobased Solvents in Asymmetric Catalysis

Miele, Margherita; Pillari, Veronica; Pace, Vittorio; Alcántara, Andrés R.; Gonzalo Calvo, Gonzalo de (Multidisciplinary Digital Publishing Institute (MDPI), 2022)
The necessity of more sustainable conditions that follow the twelve principles of Green Chemistry have pushed researchers ...
Article
Icon

Multienzymatic processes involving baeyer–villiger monooxygenases

Gonzalo Calvo, Gonzalo de; Alcántara, Andrés R. (Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Baeyer–Villiger monooxygenases (BVMOs) are flavin-dependent oxidative enzymes capable of catalyzing the insertion of an ...
Article
Icon

25th Anniversary of Molecules—Recent Advances in Green Chemistry

Gonzalo Calvo, Gonzalo de; Freire, Mara G. (Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Article
Icon

Room Temperature Ionic Liquids in Asymmetric Hetero-Ene Type Reactions: Improving Organocatalyst Performance at Lower Temperatures

Bisogno, Fabricio R.; Fernández Fernández, Rosario Fátima; Lassaletta Simón, José María; Gonzalo Calvo, Gonzalo de (MDPI, 2021)
Abstract: Room temperature ionic liquids (RTILs) have been widely used as (co)solvents in several catalytic processes ...
Article
Icon

Recent developments in the synthesis of β-diketones

Gonzalo Calvo, Gonzalo de; Alcántara, Andrés R. (Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Apart from being one of the most important intermediates in chemical synthesis, broadly used in the formation of C–C bonds ...
Article
Icon

Recent trends in synthetic enzymatic cascades promoted by alcohol dehydrogenases

Gonzalo Calvo, Gonzalo de; Paul, Caroline E. (Elsevier, 2021)
Alcohol dehydrogenases have fascinated chemists over the span of a few decades to catalyze oxidation and reduction reactions ...
Article
Icon

Positive impact of natural deep eutectic solvents on the biocatalytic performance of 5-hydroxymethyl-furfural oxidase

Gonzalo Calvo, Gonzalo de; Martin, Caterina; Fraaije, Marco Wilhelmus (Multidisciplinary Digital Publishing Institute (MDPI), 2020)
Deep eutectic solvents (DESs) have been applied as cosolvents in various biocatalytic processes during recent years. ...
Article
Icon

Deracemisation Processes Employing Organocatalysis and Enzyme Catalysis

Aranda, Carmen; Oksdath Mansilla, Gabriela; Bisogno, Fabricio R.; Gonzalo Calvo, Gonzalo de (Wiley-Blackwell, 2020)
Deracemisation methods have demonstrated their importance in the preparation of chiral compounds in the last few years. ...
Article
Icon

Biocatalyzed redox processes employing green reaction media

Aranda, Carmen; Gonzalo Calvo, Gonzalo de (Multidisciplinary Digital Publishing Institute (MDPI), 2020)
The application of biocatalysts to perform reductive/oxidative chemical processes has attracted great interest in recent ...
Article
Icon

Biocatalysis as Useful Tool in Asymmetric Synthesis: An Assessment of Recently Granted Patents (2014–2019)

Domínguez de María, Pablo; Gonzalo Calvo, Gonzalo de; Alcántara, Andrés R. (MDPI, 2019)
The broad interdisciplinary nature of biocatalysis fosters innovation, as different technical fields are interconnected ...
Article
Icon

Chemoenzymatic Dynamic Kinetic Resolution of Primary Benzylic Amines using Pd0-CalB CLEA as a Biohybrid Catalyst

Gustafson, Karl P.J.; Görbe, Tamás; Gonzalo Calvo, Gonzalo de; Yuan, Ning; Schreiber, Cynthia L.; Shchukarev, Andrey; Tai, Cheuk Wai; Persson, Ingmar; Zou, Xiaodong; Bäckvall, Jan E. (Wiley, 2019)
Herein, we report on the use a biohybrid catalyst consisting of palladium nanoparticles immobilized on cross-linked enzyme ...
Article
Icon

Cyclopentyl Methyl Ether (CPME): A Versatile Eco-Friendly Solvent for Applications in Biotechnology and Biorefineries

Gonzalo Calvo, Gonzalo de; Alcántara, Andrés R.; Domínguez de María, Pablo (Wiley, 2019)
The quest for sustainable solvents is currently a matter of intense research and development, as solvents significantly ...
Article
Icon

P450BM3-Catalyzed Oxidations Employing Dual Functional Small Molecules

Willot, Sébastien Jean-Paul; Tieves, Florian; Girhard, Marco; Urlacher, Vlada B.; Hollmann, Frank; Gonzalo Calvo, Gonzalo de (MDPI, 2019)
A set of dual functional small molecules (DFSMs) containing different amino acids has been synthesized and employed together ...
Article
Icon

Preparation of Chitosan-supported Urea Materials and their Application in Some Organocatalytic Procedures

Gonzalo Calvo, Gonzalo de; Franconetti García, Antonio; Fernández Fernández, Rosario Fátima; Lassaletta, José M.; Cabrera Escribano, Francisca (Elsevier, 2018)
An efficient and mild procedure was developed for the preparation of three chitosan-supported ureas containing ...
Article
Icon

Stereoselective enzymatic reduction of 1,4-diaryl-1,4-diones to the corresponding diols employing alcohol dehydrogenases

Mourelle Insua, Ángela; Gonzalo Calvo, Gonzalo de; Lavandera, Iván; Gotor Fernández, Vicente (MDPI, 2018)
Due to the steric hindrance of the starting prochiral ketones, the preparation of chiral 1,4-diaryl-1,4-diols through the ...
Article
Article
Icon

Lipase catalysed kinetic resolution of racemic 1,2-diols containing a chiral quaternary center

Gonzalo Calvo, Gonzalo de (MDPI, 2018)
Optically active 1,2-diols are valuable buildings blocks in organic synthesis. In the present paper, a set of racemic ...
Article
Icon

Asymmetric organocatalytic synthesis of tertiary azomethyl alcohols: key intermediates towards azoxy compounds and α-hydroxy-β-amino esters

Carmona, José A.; Gonzalo Calvo, Gonzalo de; Serrano Vallez, Inmaculada; Crespo-Peña, Ana; Šimek, Michal; Monge Fernández, David; Fernández, Rafael; Lassaletta, José M. (Royal Society of Chemistry (Great Britain), 2017)
A series of peracylated glycosamine-derived thioureas have been synthesized and their behavior as bifunctional organocatalysts ...
Article
Icon

Polycyclic Ketone Monooxygenase (PockeMO): A Robust Biocatalyst for the Synthesis of Optically Active Sulfoxides

Gonzalo Calvo, Gonzalo de; Fürst, Maximilian J. L. J.; Fraaije, Marco W. (Multidisciplinary Digital Publishing Institute (MDPI), 2017)
recently discovered, moderately thermostable Baeyer-Villiger monooxygenase, polycyclic ketone monooxygenase (PockeMO), ...
Article
Icon

Organocatalysis and Biocatalysis Hand in Hand: Combining Catalysts in One-Pot Procedures

Bisogno, Fabricio R.; López-Vidal, Martín G.; Gonzalo Calvo, Gonzalo de (Wiley, 2017)
Multi-step processes catalysed by several catalysts working concurrently have been developed in nature, thus improving ...
Article
Icon

Bacterial enzymes involved in lignin degradation

Gonzalo Calvo, Gonzalo de; Colpa, Dana I.; Habib, Mohamed H.; Fraaije, Marco Wilhelmus (Elsevier, 2016)
Lignin forms a large part of plant biomass. It is a highly heterogeneous polymer of 4-hydroxyphenylpropanoid units and is ...
Article
Icon

Biocatalytic Properties and Structural Analysis of Eugenol Oxidase from Rhodococcus jostii RHA1: A Versatile Oxidative Biocatalyst

Nguyen, Quoc‐Thai; Gonzalo Calvo, Gonzalo de; Binda, Claudia; Rioz Martínez, Ana; Mattevi, Andrea; Fraaije, Marco W. (wiley, 2016)
Eugenol oxidase (EUGO) from Rhodococcus jostii RHA1 had previously been shown to convert only a limited set of phenolic ...