idUS - Perfil del autor: Sánchez Fernández, Elena Matilde

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Nombre	Sánchez Fernández, Elena Matilde
Departamento	Química Orgánica
Área de conocimiento	Química Orgánica
Categoría profesional	Profesora Titular de Universidad
Correo electrónico	Solicitar

Nº publicaciones

17
Nº visitas

2103
Nº descargas

2415

Tipología

Orden

Publicaciones
Artículo Fluoro-labelled sp2-iminoglycolipids with immunomodulatory properties Padilla Pérez, María del Carmen; Sánchez Fernández, Elena Matilde; González-Bakker, Aday; Puerta, Adrián; Padrón, José M.; Martín-Loro, Francisco; García Fernández, José Manuel; Ortiz Mellet, Carmen (Elsevier, 2023) The unique electronic properties of the fluorine atom make its strategic incorporation into a bioactive compound a very ...
Artículo Unravelling the Inflammatory Processes in the Early Stages of Diabetic Nephropathy and the Potential Effect of (Ss)-DS-ONJ Gómez Jaramillo, Laura; Cano Cano, Fátima; Sánchez Fernández, Elena Matilde; Ortiz Mellet, Carmen; García Fernández, José Manuel; Alcalá, Martín; Álvarez Gallego, Fabiola; Iturregui, Marta; González Montelongo, M. Carmen; Campos Caro, Antonio; Arroba, Ana I.; Aguilar Diosdado, Manuel (Multidisciplinary Digital Publishing Institute (MDPI), 2022) Inflammatory processes play a central role in the pathogenesis of diabetic nephropathy (DN) in the early stages of the ...
Artículo Synthesis of sp2-Iminosugar Selenoglycolipids as Multitarget Drug Candidates with Antiproliferative, Leishmanicidal and Anti-Inflammatory Properties Sánchez Fernández, Elena Matilde; García Hernández, Raquel; Gamarro, Francisco; Arroba, Ana I.; Aguilar Diosdado, Manuel; Padrón, José M.; García Fernández, José Manuel; Ortiz Mellet, Carmen (Multidisciplinary Digital Publishing Institute (MDPI), 2021) sp2-Iminosugar glycolipids (sp2-IGLs) represent a consolidated family of glycoconjugate mimetics encompassing a ...
Artículo Anti-Inflammatory (M2) Response Is Induced by a sp2-Iminosugar Glycolipid Sulfoxide in Diabetic Retinopathy Cano Cano, Fátima; Alcalde Estévez, Elena; Gómez Jaramillo, Laura; Iturregui, Marta; Sánchez Fernández, Elena Matilde; García Fernández, José Manuel; Ortiz Mellet, Carmen; Campos Caro, Antonio; López Tinoco, Cristina (Frontiers, 2021) Diabetic retinopathy (DR) is one of the most common complications of Diabetes Mellitus (DM) and is directly associated ...
Artículo Stereoselective Synthesis of Iminosugar 2-Deoxy(thio)glycosides from Bicyclic Iminoglycal Carbamates Promoted by Cerium(IV) Ammonium Nitrate and Cooperative Brønsted Acid-Type Organocatalysis Herrera González, Irene; Sánchez Fernández, Elena Matilde; Sau, Abhijit; Nativi, Cristina; Garciá Fernández, José M.; Galán, M. Carmen; Ortiz Mellet, Carmen (American Chemical Society, 2020) The first examples of iminosugar-type 2-deoxy(thio)glycoside mimetics are reported. The key step is the activation of a ...
Artículo Synthesis, conformational analysis and: In vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragment Bermejo, Iris A; Navo, Claudio D.; Castro López, Jorge; Guerreiro, Ana; Jiménez Moreno, Ester; Sánchez Fernández, Elena Matilde; Ortiz Mellet, Carmen; Corzana, Francisco (Royal Society of Chemistry, 2020) The Tn antigen (GalNAc-α-1-O-Thr/Ser) is a well-known tumor-associated carbohydrate determinant. The use of glycopeptides ...
Artículo Thiol-ene "Click" Synthesis and Pharmacological Evaluation of C-Glycoside sp2-Iminosugar Glycolipids Sánchez Fernández, Elena Matilde; García Moreno, M. Isabel; García Hernández, Raquel; Padrón, José M.; García Fernández, José Manuel; Gamarro, Francisco; Ortiz Mellet, Carmen (MDPI, 2019) The unique stereoelectronic properties of sp2-iminosugars enable their participation in glycosylation reactions, thereby ...
Artículo Nuevas estrategias en el proceso de enseñanza-aprendizaje de la asignatura Experimentación Química II del Grado en Ingeniería Química Industrial Sánchez Fernández, Elena Matilde (Universidad de Sevilla, 2018) El trabajo realizado durante el desarrollo del ciclo de mejora experimentado en la asignatura Experimentación en Química ...
Artículo Fluorinated chaperone-ß-cyclodextrin formulations for ß-glucocerebrosidase activity enhancement in neuronopathic Gaucher disease García Moreno, M. Isabel; Mata, Mario de la; Sánchez Fernández, Elena Matilde; Benito, Juan M.; Díaz Quintana, Antonio Jesús; Fustero, Santos; Nanba, Eiji; Higaki, Katsumi; Sánchez-Alcazar, José Antonio; García Fernández, José Manuel; Ortiz Mellet, Carmen (American Chemical Society, 2017) Amphiphilic glycomimetics encompassing a rigid, undistortable nor-tropane skeleton based on 1,6-anhydro-L-idonojirimycin ...
Tesis Doctoral Glicoterapias contra el cáncer, la leishmania y enfermedades de depósito lisosomal Gonçalves Pereira, Rita Alexandra; Sánchez Fernández, Elena Matilde; García Fernández, José Manuel; Ortiz Mellet, Carmen (2016)
Artículo Conformationally-Locked C-Glycosides: Tuning Aglycone Interactions for Optimal Cheperone Behaviour in Gaucher Fibroblasts Navo, C.D.; Corzana, F.; Sánchez Fernández, Elena Matilde; Busto, J.H.; Avenoza, A.; Namba, E.; Higaki, Katsumi; Ortiz Mellet, Carmen; García Fernández, José Manuel; Peregrina, J.M. (Royal Society of Chemistry, 2016) A series of conformationally locked C-glycosides based on the 3-aminopyrano[3,2-b]pyrrol-2(1H)-one (APP) scaffold has been ...
Artículo Glycomimetic-based pharmacological chaperones for lysosomal storage disorders: lessons from Gaucher, GM1-gangliosidosis and Fabry diseases Sánchez Fernández, Elena Matilde; García Fernández, José Manuel; Ortiz Mellet, Carmen (Royal Society of Chemistry, 2016) Lysosomal storage disorders (LSDs) are often caused by mutations that destabilize native folding and impair the trafficking ...
Trabajo Fin de Máster Iminoazúcares sp2 en inmunoterapias contra el cáncer Guillén Poza, Pablo Adrián; Ortiz Mellet, Carmen; Sánchez Fernández, Elena Matilde (2016) En la actualidad, los tratamientos más utilizados para combatir el cáncer se basan en el uso de quimioterapia, radioterapia ...
Artículo Antileishmanial activity of sp2-iminosugar derivatives Sánchez Fernández, Elena Matilde; Gómez Pérez, Veronica; García Hernández, Raquel; García Fernández, José Manuel; Plata, Gabriela B.; Padrón, José M.; Ortiz Mellet, Carmen; Catanys, Santiago; Gamarro, Francisco (Royal Society of Chemistry, 2015) A series of sp2-iminosugar-type glycomimetics bearing S-linked pseudoglycoside substituents (sulfide, sulfoxide and sulfone ...
Artículo New Castanospermine Glycoside Analogues Inhibit Breast Cancer Cell Proliferation and Induce Apoptosis without Affecting Normal Cells Allan, Ghada; Ouadid-Ahidouch, Halima; Sánchez Fernández, Elena Matilde; Risquez Cuadrado, Rocío; García Fernández, José Manuel; Ortiz Mellet, Carmen; Ahidouch, Ahmed (Public Library of Science, 2013) sp2-Iminosugar-type castanospermine analogues have been shown to exhibit anti-tumor activity. However, their effects on ...
Patente Derivados sp2, imnoazúcar como inhibidores de las alfa-glicosidasas. Garcia Fernandez, Jose M.; Risquez-Cuadro, Rocio; Sánchez Fernández, Elena Matilde; Ortiz Mellet, Carmen (Oficina Española de Patentes y Marcas , 2011) Derivados sp2 imnoazúcar como inhibidores de las ?-glicosidasas.Derivados glicosilados de fórmula I, donde los significados ...
Artículo sp2-Iminosugar Glycolipids as Inhibitors of Lipopolysaccharide-mediated Human Dendritic Cell Activation in Vitro and of Acute Inflammation in Mice in Vivo Schaeffer, Evelyne; Sánchez Fernández, Elena Matilde; Gonçalves-Pereira, Rita; Flacher, Vincent; Lamon, Delphine; Duval, Monique; Fauny, Jean Daniel; García Fernández, José Manuel; Mueller, Christopher G.; Ortiz Mellet, Carmen (Elsevier, 219) Glycolipid mimetics consisting of a bicyclic polyhydroxypiperidine-cyclic carbamate core and a pseudoanomeric hydrophobic ...