Author profile: Miguel Rodríguez, Manuel de
Institutional data
Name | Miguel Rodríguez, Manuel de |
Department | Citología e Histología Normal y Patológica |
Knowledge area | Histología |
Professional category | Catedrático de Universidad |
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No. publications
40
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No. visits
6315
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13312
Publications |
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Article
Effects of polyphenolic maqui ( Aristotelia chilensis ) extract on the inhibition of NLRP3 inflammasome and activation of mast cells in a mouse model of Crohn's disease-like colitis
(Frontiers Media S.A., 2024)
Introduction: Crohn’s disease (CD) involves activation of mast cells (MC) and NFкB in parallel with the PPAR-a/NLRP3 ... |
Article
Native Chilean Berries Preservation and In Vitro Studies of a Polyphenol Highly Antioxidant Extract from Maqui as a Potential Agent against Inflammatory Diseases
(MDPI, 2021)
The best conservation method for native Chilean berries has been investigated in combination with an implemented large-scale ... |
Article
Quantification of Boron Compound Concentration for BNCT Using Positron Emission Tomography
(MDPI, 2020)
Boron neutron capture therapy requires a 2 mM 10B concentration in the tumor. The well-known BNCT patient treatment method ... |
Article
Mitochondrial imbalance as a new approach to the study of fibromyalgia
(Dovepress, 2020)
Background: Fibromyalgia (FM) is a common chronic pain disease, whose pathogenic mechanism still remains elusive. Oxidative ... |
Article
Polyphenolic Maqui Extract as a Potential Nutraceutical to Treat TNBS-Induced Crohn' s Disease by the Regulation of Antioxidant and Anti-Inflammatory Pathways
(MDPI, 2020)
Nutraceuticals include a wide variety of bioactive compounds, such as polyphenols, which have been highlighted for their ... |
PhD Thesis
Nuevas terapias bioactivas preventivas y terapéuticas en un modelo animal de enfermedad de Crohn
(2019)
La enfermedad inflamatoria intestinal (EII), como la enfermedad de Crohn (EC) y la colitis ulcerosa (CU), son un trastorno ... |
PhD Thesis |
Article
Fibroblasts Collagen Production and Histological Alterations in Hereditary Gingival Fibromatosis
(MDPI, 2019)
Hereditary gingival fibromatosis is a disorder for which the etiology remains unknown. We aimed to evaluate the fibroblasts ... |
Article
Preclinical [18F]tetrafluoroborate-PET/CT imaging of pituitary gland hyperplasia
(Oxford, 2018)
By blocking of sodium–iodide symporter (NIS) in thyroid gland with potassium perchlorate administered in drinking water ... |
Article
Amitriptyline down-regulates coenzyme Q10 biosynthesis in lung cancer cells
(Elsevier, 2017)
Amitriptyline, a tricyclic antidepressant, has been proposed as an antitumoral drug in oxidative therapy. Its ... |
Article
Fibromyalgia syndrome and temporomandibular disorders with muscular pain. A review
(2017)
Objectives: Temporomandibular disorders (TMD) refer to a group of clinical picture affecting the masticatory muscles and ... |
Article
Amitriptyline induces mitophagy that precedes apoptosis in human HepG2 cells
(2016)
Systemic treatments for hepatocellular carcinoma (HCC) have been largely unsuccessful. This study investigated the antitumoral ... |
PhD Thesis
Influencia de los parámetros mitocondriales en el agradamiento gingival inducido por ciclosporina y nifedipina: ensayo sobre modelo animal
(2016)
El agrandamiento gingival es una entidad patológica englobada dentro de la clasificación de la enfermedad periodontal. Las ... |
Article
Targeted multifunctional tannic acid nanoparticles
(The Royal Society of Chemistry, 2016)
Tannic acid (TA) has multiple effects against cancer, being especially promising in those types that overexpress the ... |
Patent. Invention
Modelo de roedor para fibromialgia y dolor crónico
(Oficina Española de Patentes y Marcas (OEPM), 2015)
El objeto de la presente invención se refiere a un modelo de roedor para fibromialgia y dolor crónico, inducido por ... |
Article
Coenzyme Q(10) Therapy
(KARGER, 2014)
For a number of years, coenzyme Q 10 (CoQ 10 ) was known for its key role in mitochondrial bioenergetics; later ... |
Master's Final Project |
Article
Apoptotic microtubules delimit an active caspase free area in the cellular cortex during the execution phase of apoptosis
(NATURE PUBLISHING GROUP, 2013)
Apoptotic microtubule network (AMN) is organized during apoptosis, forming a cortical structure beneath plasma membrane, which ... |
Article
Is Inflammation a Mitochondrial Dysfunction-Dependent Event in Fibromyalgia?
(Mary Ann Liebert, Inc., 2013)
Fibromyalgia (FM) is a complex disorder that affects up to 5% of the general population worldwide. Both mitochondrial ... |
Article |
Article
Melatonin-synthesizing enzymes and melatonin receptor in rat thyroid cells
(Universidad de Murcia. Departamento de Biología Celular e Histología, 2012)
Melatonin is an indoleamine with a wide spectrum of biological activities other than transmitting photoperiod information, ... |
Article |
Article
Oxidative Stress Correlates with Headache Symptoms in Fibromyalgia: Coenzyme Q10 Effect on Clinical Improvement
(Public Library of Science, 2012)
Background: Fibromyalgia (FM) is a chronic pain syndrome with unknown etiology and a wide spectrum of symptoms such as ... |
Patent. Invention
Uso de amitriptilina como agente antitumoral para el tratamiento de cáncer de pulmón.
(Oficina Española de Patentes y Marcas , 2011)
Uso de amitriptilina como agente antitumoral para el tratamiento de cáncer de pulmón.Composición farmacéutica que comprende ... |
PhD Thesis
Estudio etiopatogénico del linfoepitelioma no endémico
(2011)
El carcinoma nasofaríngeo (CNF) es una neoplasia que tiene una alta incidencia en China y algunas áreas del sudeste asiático, ... |
Article
Clinical symptoms in fibromyalgia are better associated to lipid peroxidation levels in blood mononuclear cells rather than in plasma
(Public Library of Science, 2011)
Background: We examined lipid peroxidation (LPO) in blood mononuclear cells (BMCs) and plasma, as a marker of oxidative ... |
Article
The cadherin–catenin complex in nasopharyngeal carcinoma
(SPRINGER, 2011)
Abnormal Wnt signaling and impaired cell–cell adhesion due to abnormal E-cadherin and b-catenin func tion have been ... |
Article
Inmunohistochemical Profile of Solid Cell Nest of Thyroid Gland
(Humana Press Inc., 2011)
It It is widely held that solid cell nests (SCN) of the thyroid are ultimobranchial body remnants. SCNs are composed of ... |
PhD Thesis
Estudio molecular del cáncer de tiroides experimental
(2010)
La tiroides es una glándula endocrina de origen ectodérmico que se desarrolla precozmente en la porción cefálica del tubo ... |
Article
Acute oxidant damage promoted on cancer cells by amitriptyline in comparison with some common chemotherapeutic drugs
(Wolters Kluwer Health, 2010)
Oxidative therapy is a relatively new anticancer strategy based on the induction of high levels of oxidative stress, achieved ... |
PhD Thesis
Aproximación al estudio biomolecular del carcinoma nasofaríngeo
(2010)
El carcinoma nasofaríngeo se presenta con baja incidencia en los países occidentales, siendo muy frecuente en países ... |
Article
Mitochondrial dysfunction and mitophagy activation in blood mononuclear cells of fibromyalgia patients: implications in the pathogenesis of the disease
(BioMed Central, 2010)
Introduction: Fibromyalgia is a chronic pain syndrome with unknown etiology. Recent studies have shown some evidence ... |
Article
Thyrotropin-releasing hormone receptor expression in thyroid follicular cells: a new paracrine role of C-cells?
(Universidad de Murcia. Departamento de Biología Celular e Histología, 2005)
Thyrotropin-releasing hormone (TRH) synthesized in the hypothalamus has the capability of inducing the release of ... |
Article
Contribution of the microvessel network to the clonal and kinetic profiles of adrenal cortical proliferative lesions
(W.B. Saunders Co., 2001)
Monoclonal adrenocortical lesions have been characterized by an inverse correlation between proliferation and apoptosis, ... |
Article
Germline RET 634 Mutation Positive MEN 2A-related C-Cell Hyperplasias Have Genetic Features Consistent with Intraepithelial Neoplasia
(The Endocrine Society, 2001)
C-cell hyperplasias are normally multifocal in multiple endocrine neoplasia type 2A. We compared clonality, microsatellite ... |
Article
Clonal patterns in phaeochromocytomas and MEN-2A adrenal medullary hyperplasias: histological and kinetic correlates
(John Wiley & Sons, 2000)
The relationship among histological features, cell kinetics, and clonality has not been studied in adrenal medullary ... |
Article
cDNA Sequence and Genomic Structure of the Rat Ret Proto-Oncogene
(Informa Healthcare, 2000)
The RET proto-oncogene, a member of the Receptor Tyrosine Kinase family, plays a crucial role during the development of ... |
Article
Kinetic profiles of intraepithelial and invasive prostatic neoplasias: the key role of down-regulated apoptosis in tumor progression
(Springer, 2000)
The cell kinetic of prostatic intraepithelial neoplasia (PIN) is poorly understood. Herein we report the kinetic pattern ... |
Article
Clonality as Expression of Distinctive Cell Kinetics Patterns in Nodular Hyperplasias and Adenomas of the Adrenal Cortex
(Elsevier Science, 2000)
Although histopathologic criteria for adrenal cortical nodular hyperplasias (ACNHs) and adenomas (ACAs) have been developed, ... |
PhD Thesis
Análisis de ADN y cuantificación de la microvascularización en lesiones proliferativas córtico-suprarrenales
(1996)
En varias neoplasias de origen endocrino o neuroendocrino, existe el dilema de la clasificación correcta en cuanto a su ... |