Perfil del autor: López Barneo, José
Datos institucionales
| Nombre | López Barneo, José |
| Departamento | Fisiología Médica y Biofísica |
| Área de conocimiento | Fisiología |
| Categoría profesional | Profesor Emérito |
| Correo electrónico | Solicitar |
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Estadísticas
-
Nº publicaciones
115
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Nº visitas
20258
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Nº descargas
27447
| Publicaciones |
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Artículo
 Protection and repair of the nigrostriatal pathway with stem-cell-derived carotid body glomus cell transplants in chronic MPTP Parkinsonian model
(MDPI, 2023)
Antiparkinsonian carotid body (CB) cell therapy has been proven to be effective in rodent and nonhuman primate models of ... |
Artículo
Full protection from SARS-CoV-2 brain infection and damage in susceptible transgenic mice conferred by MVA-CoV2-S vaccine candidate
(Nature Publishing Group, 2023)
Vaccines against SARS-CoV-2 have been shown to be safe and effective but their protective efficacy against infection in ... |
Artículo
Transgenic NADH dehydrogenase restores oxygen regulation of breathing in mitochondrial complex I-deficient mice
(NATURE PUBLISHING GROUP, 2023)
The hypoxic ventilatory response (HVR) is a life-saving reflex, triggered by the activation of chemoreceptor glomus cells ... |
Tesis Doctoral
Participación de la mitocondria en la biología de los progenitores neurales y la sensibilidad al oxígeno en los quimiorreceptores arteriales
(2022)
Las mitocondrias son orgánulos que asumen tareas muy diversas y de gran relevancia para la célula eucariota y la homeostasis ... |
Artículo
Oxygen regulation of breathing is abolished in mitochondrial complex III-deficient arterial chemoreceptors
(National Academy of Sciences, 2022)
Acute oxygen (O2) sensing is essential for adaptation of organisms to hypoxic environments or medical conditions with ... |
Artículo
Reduced expression of mitochondrial complex I subunit Ndufs2 does not impact healthspan in mice
(Nature Publishing Group, 2022)
Aging in mammals leads to reduction in genes encoding the 45-subunit mitochondrial electron transport chain complex I. ... |
Artículo
Succinate dehydrogenase/complex II is critical for metabolic and epigenetic regulation of T cell proliferation and inflammation
(American Association for the Advancement of Science, 2022)
Effective T cell-mediated immune responses require the proper allocation of metabolic resources to sustain growth, ... |
Artículo
Editorial: Hypoxia and Cardiorespiratory Control
(Frontiers Media, 2021)
To maintain adequate oxygen levels in the body, which is essential for a healthy life, the respiratory and cardiovascular ... |
Artículo
Is Carotid Body Infection Responsible for Silent Hypoxemia in COVID-19 Patients?
(Oxford University Press (OUP), 2021)
|
Artículo
Using redox-sensitive fluorescent probes to record real-time reactive oxygen species production in cells from mouse carotid body slices
(Cell Press, 2021)
Reactive oxygen species (ROS) are important signaling molecules for physiologic processes such as acute response to hypoxia. ... |
Artículo
Unexpected obesity, rather than tumorigenesis, in a conditional mouse model of mitochondrial complex II deficiency
(Federation amer soc exp biol, 2021)
Mutations in any of the genes encoding the four subunits of succinate dehydrogenase (SDH), a mitochondrial membrane-bound ... |
Artículo
Hypoxia compromises the mitochondrial metabolism of Alzheimer’s disease microglia via HIF1
(Springer, 2021)
Genetic Alzheimer’s disease (AD) risk factors associate with reduced defensive amyloid β plaque-associated microglia (AβAM), ... |
Artículo
Lactate sensing mechanisms in arterial chemoreceptor cells
(2021)
Classically considered a by-product of anaerobic metabolism, lactate is now viewed as a fundamental fuel for oxidative ... |
Artículo
Neurotransmitter Modulation of Carotid Body Germinal Niche
(MDPI AG, 2020)
The carotid body (CB), a neural-crest-derived organ and the main arterial chemoreceptor in mammals, is composed of clusters ... |
Artículo
Cellular adaptation to oxygen deficiency beyond the Nobel award
(Willey, 2020)
Understanding the cellular adaptation to oxygen deficiency -hypoxia- has a profound impact on our knowledge of the ... |
Artículo
Molecular mechanisms of acute oxygen sensing by arterial chemoreceptor cells. Role of Hif2α
(Frontiers Research Foundation, 2020)
Carotid body glomus cells are multimodal arterial chemoreceptors able to sense and integrate changes in several physical ... |
Artículo
Molecular targets for endogenous glial cell line-derived neurotrophic factor modulation in striatal parvalbumin interneurons
(Oxford University Press, 2020)
Administration of recombinant glial cell line-derived neurotrophic factor into the putamen has been tested in preclinical ... |
| Tesis Doctoral |
Patente. Invención
Composiciones capaces de modular la estimulación de GDNF endógeno para el tratamiento de enfermedades neurodegenerativas
(Organización Mundial de la Propiedad Intelectual (OMPI), 2019)
Compuestos y composiciones capaces de modular la estimulación de GDNF endógeno mediante la activación de los genes GPR83, ... |
| Tesis Doctoral |
Artículo
Mitochondrial Complex I Function Is Essential for Neural Stem/Progenitor Cells Proliferation and Differentiation
(Frontiers Research Foundation, 2019)
Neurogenesis in developing and adult mammalian brain is a tightly regulated process that relies on neural stem cell (NSC) ... |
Artículo
HIF-2a is essential for carotid body development and function
(eLife Sciences Publications, 2018)
Mammalian adaptation to oxygen flux occurs at many levels, from shifts in cellular metabolism to physiological adaptations ... |
Artículo
Gene expression analyses reveal metabolic specifications in acute O-2-sensing chemoreceptor cells
(Wiley, 2017)
Acute O2sensing is a fundamental property of cells in the peripheral chemoreceptors,e.g. glomus cells in the carotid body ... |
Artículo
Genetic Rescue of Mitochondrial and Skeletal Muscle Impairment in an Induced Pluripotent Stem Cells Model of Coenzyme Q10 Deficiency
(Wiley-Blackwell, 2017)
Coenzyme Q10 (CoQ10) plays a crucial role in mitochondria as an electron carrier within the mitochondrial respiratory chain ... |
Artículo
Highly efficient neural conversion of human pluripotent stem cells in adherent and animal-free conditions
(Wiley, 2017)
Neural differentiation of human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) can produce a ... |
Artículo
Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-β Peptide Generation In Vivo
(Public Library of Science, 2017)
Background Recent epidemiological evidence has linked hypoxia with the development of Alzheimer disease (AD). A number ... |
Artículo
Selective accumulation of biotin in arterial chemoreceptors: requirement for carotid body exocytotic dopamine secretion
(2016)
Biotin is a water-soluble vitamin required for the function of carboxylases as well asfor the regulation of gene expression. ... |
Artículo
Striatal GDNF Production Is Independent to Circulating Estradiol Level Despite Pan- Neuronal Activation in the Female Mouse.
(2016)
Gender difference in Parkinson’s disease (PD) suggests that female sex steroids may promote dopaminergic neuron survival ... |
Artículo
Gene expression profiling supports the neural crest origin of adult rodent carotid body stem cells and identifies CD10 as a marker for mesectoderm-committed progenitors
(WILEY, 2016)
Neural stem cells (NSCs) are promising tools for understanding nervous system plasticity and repair, but their use is ... |
Artículo
Carotid body oxygen sensing and adaptation to hipoxia
(Springer, 2015)
The carotid body (CB) is the principal arterial chemoreceptor that mediates the hyperventilatory response to hypoxia. Our ... |
Tesis Doctoral
 Mecanismos moleculares de la sensibilidad aguda al oxígeno en los quimiorreceptores arteriales: función del complejo I mitocondrial
(2015)
El oxígeno (O2) es una molécula esencial para la vida de los animales debido a su metabolismo celular aeróbico, ya que la ... |
Artículo
Resistance of subventricular neural stem cells to chronic hypoxemia despite structural disorganization of the germinal center and impairment of neuronal and oligodendrocyte survival
(Dove Medical Press Ltd., 2015)
Chronic hypoxemia, as evidenced in de-acclimatized high-altitude residents or in patients with chronic obstructive respiratory ... |
Tesis Doctoral
Mecanismos Moleculares de Formación de Tumores en Modelos Genéticos Animales con Defectos Mitocondriales por Deleción del Gen SdhD
(2015)
La disfunción mitocondrial está ampliamente vinculada con la tumorogénesis. Una de las características principales de las ... |
Artículo
Glucose sensing by carotid body glomus cells: potential implications in disease
(Frontiers Media, 2014)
The carotid body (CB) is a key chemoreceptor organ in which glomus cells sense changes in blood O2, CO2, and pH levels. ... |
Tesis Doctoral
Hipertrofia del cuerpo carotídeo en hipoxia crónica: mecanismos de activación, proliferación y diferenciación de los progenitores neurales en el sistema nervioso periférico
(2014)
The goal of this doctoral thesis is to achieve a better understanding of the biology and behavior of the recently discovered ... |
Artículo
An O-2-sensitive glomus cell-stem cell synapse induces carotid body growth in chronic hipoxia
(CELL PRESS, 2014)
Neural stem cells (NSCs) exist in germinal centers of the adult brain and in the carotid body (CB), an oxygen-sensing organ ... |
Artículo
Effect of hypoxia on lung gene expression and proteomic profile: insights into the pulmonary surfactant response
(Elsevier, 2014)
Exposure of lung to hypoxia has been previously reported to be associated with significant alterations in the protein ... |
Artículo
Deletion of the von Hippel-Lindau gene causes sympathoadrenal cell death and impairs chemoreceptor-mediated adaptation to hypoxia
(Wiley, 2014)
Mutations of the von Hippel–Lindau (VHL) gene are associated with pheochromocytomas and paragangliomas, but the role of ... |
| Artículo |
Patente. Invención
Procedimiento para detectar el precipitado de x-gal u otros precipitados opacos mediante microscopia confocal
(Oficina Española de Patentes y Marcas , 2013)
La presente solicitud de patente se refiere a un procedimiento para la obtención de imágenes confocales de la tinción ... |
Artículo
Age-mediated transcriptomic changes in adult mouse substantia nigra
(2013)
Substantia nigra pars compacta (SNpc) is highly sensitive to normal aging and selectively degenerates in Parkinson’s disease ... |
| Artículo |
Capítulo de Libro
Carotid Body Transplants as a Therapy for Parkinson’s Disease
(The Royal Society of Chemistry, 2013)
Affecting over 1.5 million people across the world, Parkinson's disease is a progressive neurological condition characterized, ... |
| Artículo |
Artículo
Prolyl Hydroxylase-dependent Modulation of Eukaryotic Elongation Factor 2 Activity and Protein Translation under Acute Hypoxia
(American Society for Biochemistry and Molecular Biology, 2012)
Early adaptive responses to hypoxia are essential for cell survival, but their nature and underlying mechanisms are poorly ... |
Artículo
Differential impairment of catecholaminergic cell maturation and survival by genetic mitochondrial complex II dysfunction
(2012)
The SDHD gene (subunit D of succinate dehydrogenase) has been shown to be involved in the generation of paragangliomas and ... |
Tesis Doctoral
Generación y análisis del ratón mutante condicional en la subunidad D del complejo II mitocondrial: efecto sobre el sistema nervioso central y el periférico
(2012)
SDHD es un gen supresor de tumores en humanos. Este gen codifica para una (SDHD) de las cuatro proteínas que forman parte ... |
| Artículo |
Artículo
GDNF Is predominantly expressed in the PV+ neostriatal interneuronal ensemble in normal mouse and after Injury of the nigrostriatal pathway
(2012)
Glial cell line-derived neurotrophic factor (GDNF) is absolutely required for survival of dopaminergic (DA) nigrostriatal ... |
Tesis Doctoral
Participación de hemoproteínas en la función uimiosensora de células neurosecretoras
(2011)
En los mamíferos existe un sistema homeostático de tejidos con células sensibles a las variaciones en los niveles sanguíneos ... |
Capítulo de Libro
La fisiología celular, los canales iónicos y la creación de una biofísica española
(Manuel Cortijo Mérida, 2011)
|
Capítulo de Libro
Neuroprotection in Parkinson’s Disease
(Royal Society of Chemistry, 2011)
|
Artículo
Functional and transcriptional induction of Aquaporin-1 gene by hypoxia; analysis of promoter and role of Hif-1α
(2011)
Aquaporin-1 (AQP1) is a water channel that is highly expressed in tissues with rapid O2 transport. It has been reported ... |
Artículo
 The carotid body, a neurogenic niche in the adult peripheral nervous system
(Univ pisa, 2010)
We have described a new population of adult neural stem cells residing in the carotid body, a chemoreceptor organ in the ... |
Capítulo de Libro
Clinical applications of cell therapy
(Edikamed, 2010)
|
Artículo
Carotid body chemosensory responses in mice deficient of TASK channels
(2010)
Background K+ channels of the TASK family are believed to participate in sensory transduction by chemoreceptor (glomus) ... |
Artículo
First aid kit for hypoxic survival: sensors and strategies
(University of Chicago Press, 2010)
Survival success under conditions of acute oxygen deprivation depends on efficiency of the central and peripheral ... |
Patente. Invención
Células madre derivadas del cuerpo carotideo y usos de las mismas
(Oficina Española de Patentes y Marcas , 2009)
Células madre derivadas del cuerpo carotídeo y usos de las mismas caracterizadas porque son positivas para el marcador ... |
Tesis Doctoral
Hipoxia en cardiomiocitos; regulación de la expresión de la subunidad b1 del canal maxi-k y participación en el precondicionamiento cardíaco
(2009)
The presence of maxi-K channels has been reported in the mitochondria of the cardiac myocytes where it plays a cytoprotective ... |
Patente. Invención
Método y kit de diagnóstico para la determinación cuantitativa de la expresión del canal maxi-K
(Oficina Española de Patentes y Marcas (OEPM), 2009)
Método y kit de diagnóstico para la determinación cuantitativa de la expresión del canal maxi-K. La presente invención se ... |
Artículo
Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice
(2008)
Cell culture studies have implicated the oxygen-sensitive hypoxia-inducible factor (HIF) prolyl hydroxylase PHD3 in the ... |
Tesis Doctoral
GDNF y cuerpo carotídeo: implicaciones funcionales y uso en terapia celular
(2007)
El proyecto que se desarrolla en esta Tesis Doctoral se ha centrado en el estudio de los mecanismos celulares y moleculares ... |
Tesis Doctoral
Quimiorrecepción del CO2 en la médula adrenal y facilitación de la permeabilidad a O2 por la acuaporina-1
(2007)
El desarrollo de esta Tesis se ha centrado en el estudio de los mecanismos celulares que permiten la quimiotransducción ... |
Artículo
Development of cytosolic hypoxia and hypoxia-inducible factor stabilization are facilitated by aquaporin-1 expression
(Elsevier, 2007)
O2 is essential for aerobic life, and the classic view is that it diffuses freely across the plasma membrane. However, ... |
Tesis Doctoral
Neuroprotección en un nuevo modelo de animal transgénico
(2006)
El objetivo general de este proyecto fue analizar en un modelo de parkinsonismo experimental en ratones, si el aumento del ... |
Tesis Doctoral
Acoplamiento excitación-contracción en músculo liso: nuevo papel metabotrópico de los canales de calcio en la regulación del tono vascular
(2006)
El músculo liso es un tejido que se encuentra generalmente recubriendo órganos (músculo liso visceral: tubo digestivo, ... |
Artículo
Metabotropic Ca2+ channel-induced Ca2+ release and ATP-dependent facilitation of arterial myocyte contraction
(2006)
Voltage-gated Ca2_ channels in arterial myocytes can mediate Ca2_ release from the sarcoplasmic reticulum and, thus, induce ... |
Ponencia
Oxygen-sensing by ion channels and mitochondrial function in carotid body glomus cells
(John Wiley & Sons, 2006)
Carotid body glomus cells release transmitters in response to hypoxia due to the increase of excitability resulting from ... |
Artículo
Acute oxygen sensing in heme oxygenase-2 null mice
(2006)
Hemeoxygenase-2 (HO-2) is an antioxidant enzyme that can modulate recombinant maxi-K+ channels and has been proposed to ... |
Tesis Doctoral
Regulación de la expresión génica de canales iónicos por hipoxia crónica en células cromafines
(2005)
El objetivo general de este proyecto fue el estudio de la regulación por hipoxia de la expresión de genes que codifican ... |
Tesis Doctoral
Células neurosecretoras sensoras de oxígeno y glucosa
(2005)
El mantenimiento de un medio interno estable, u homesotasia, es especial para los seres vivos. Por ello existen sistemas ... |
Artículo
Rat Adrenal Chromaffin Cells Are Neonatal CO2 Sensors
(2005)
We studied the participation of adrenal medulla (AM) chromaffin cells in hypercapnic chemotransduction. Using amperometric ... |
Artículo
Selective Glial Cell Line-Derived Neurotrophic Factor Production in Adult Dopaminergic Carotid Body Cells In Situ and after Intrastriatal Transplantation
(2005)
Glial cell line-derived neurotrophic factor (GDNF) exerts a notable protective effect on dopaminergic neurons in rodent ... |
| Artículo |
Artículo
MECHANISMS OF DISEASE Acute Oxygen-Sensing Mechanisms
(Massachusetts Medical Society, 2005)
JOSEPH PRIESTLEY, ONE OF THE THREE SCIENTISTS CREDITED WITH THE discovery of oxygen, described the death of mice that were ... |
| Artículo |
Artículo
Regulation of oxygen sensing by ion channels
(2004)
O2 sensing is of critical importance for cell survival and adaptation of living organisms to changing environments or ... |
Artículo
The Mitochondrial SDHD Gene Is Required for Early Embryogenesis, and Its Partial Deficiency Results in Persistent Carotid Body Glomus Cell Activation with Full Responsiveness to Hypoxia
(2004)
The SDHD gene encodes one of the two membrane-anchoring proteins of the succinate dehydrogenase (complex II) of the ... |
Artículo
Rotenone selectively occludes sensitivity to hypoxia in rat carotid body glomus cells
(Wiley-Blackwell Publishing Ltd., 2003)
Carotid body glomus cells release transmitters in response to hypoxia due to the increase of excitability resulting from ... |
Artículo
Trophic restoration of the nigrostriatal dopaminergic pathway in long-term carotid body-grafted parkinsonian rats
(2003)
We studied the mechanisms underlying long-term functional recovery of hemiparkinsonian rats grafted intrastriatally with ... |
Tesis Doctoral
Sensibilidad a hipoxia e hipoglucemia de células glómicas en rodajas de cuerpo carotídeo
(2000)
Los objetivos generales del presente trabajo fueron los siguientes: 1. Puesta a punto de la preparación de rodajas finas ... |
Tesis Doctoral
Homeostasis del calcio en miocitos del árbol arterial pulmonar
(2000)
En el presente trabajo se ha estudiado la homeostasis de la (Ca2+) i en miocitos aislados de la arteria pulmonar y el ... |
Patente. Invención
Método de aislamiento de un agregado celular y agregado celular resultante
(Oficina Española de Patentes y Marcas , 2000)
Método de aislamiento de un agregado celular y agregado celular resultante.La invención se refiere al uso de células o ... |
Artículo
Collapse of conductance Is prevented by a Glutamate residue conserved in voltage-dependent K+ channels
(2000)
Voltage-dependent K 1 channel gating is influenced by the permeating ions. Extracellular K 1 determines the occupation of ... |
Artículo
Secretory responses of intact glomus cells in thin slices of rat carotid body to hypoxia and tetraethylammonium
(2000)
We have developed a thin-slice preparation of whole rat carotid body that allows us to perform patch-clamp recording of ... |
Patente. Invención
Utilización en composiciones farmacológicas de agentes con efecto reductor o inductor de hipoxia
(Oficina Española de Patentes y Marcas (OEPM), 1999)
Utilización en composiciones farmacológicas de agentes con efecto reductor o inductor de hipoxia. Se propone como nueva ... |
| Tesis Doctoral |
| Artículo |
Artículo
A Small Domain in the N Terminus of the Regulatory a-Subunit Kv2.3 Modulates Kv2.1 Potassium Channel Gating
(1999)
Recent work has demonstrated the existence of regulatory K1 channel a-subunits that are electrically silent but capable ... |
| Tesis Doctoral |
Artículo
Identification and Functional Characterization of a K1 Channel a- Subunit with Regulatory Properties Specific to Brain
(1997)
The physiological diversity of K1 channels mainly depends on the expression of several genes encoding different a-subunits. ... |
Artículo
Oxygen sensing by ion channels and chemotransduction in single glomus cells
(1996)
We have monitored cytosolic [Ca2+] and dopamine release in intact fura-2-loaded glomus cells with microfluoroimetry and a ... |
Artículo
Oxygen-sensitive calcium channels in vascular smooth muscle and their possible role in hypoxic arterial relaxation
(1995)
We have investigated the modifications of cytosolic [Ca2+] and the activity of Ca2+ channels in freshly dispersed arterial ... |
Artículo
Hypoxia induces voltage-dependent Ca2+ entry and quantal dopamine secretion in carotid body glomus cells
(1994)
We have investigated the changes of cytosolic [Ca2+1 and the secretory -activity in single glomus cells dispersed from ... |
Tesis Doctoral
Adaptación y modificaciones de corta y larga duración en la actividad eléctrica de neuronas de la corteza cerebral in vitro
(1993)
El sistema nervioso central lleva a cabo sus complejas funciones gracias a la actividad armónica de sus unidades básicas, ... |
Artículo
Gating of O2-sensitive K + Channels of Arterial Chemoreceptor Cells and Kinetic Modifications Induced by Low PO2
(1992)
We have studied the kinetic properties of the O2-sensitive K+ channels (KO2 channels) of dissociated glomus cells from ... |
Artículo
Potassium Channel Types in Arterial Chemoreceptor Cells and Their Selective Modulation by Oxygen
(1992)
Single K+ channel currents were recorded in excised membrane patches from dispersed chemoreceptor cells of the rabbit ... |
Tesis Doctoral
Canales de calcio de las células glómicas y su modulación por dopamina
(1991)
El presente trabajo se centra en el estudio de los canales de Ca2+ de alto umbral y de su modulación metabólica y por ... |
Artículo
Single K+ channels in membrane patches of arterial chemoreceptor cells are modulated by 02 tension
(1991)
Type I cells of the carotid body are known to participate in the detection of 02 tension in arterial blood but the primary ... |
Artículo
Sodium and Calcium Currents in Dispersed Mammalian Septal Neurons
(1991)
Voltage-gated Na+ and Ca2+ conductances of freshly dissociated septal neurons were studied in the whole-cell configuration ... |
Tesis Doctoral
Efecto de la estimulación eléctrica periférica sobre la evolución del dolor lumbar
(1990)
El presente trabajo trata sobre la evolución del dolor lumbar al ser tratado con estimulación eléctrica periférica ... |
Artículo
Thyrotropin-releasing-hormone (TRH) and its physiological metabolite TRH-OH inhibit Na+ channel activity in mammalian septal neurons
(1990)
The interaction of thyrotropin-releasing hormone (TRH) and its physiological metabolite TRH-OH with Na+ channels was studied ... |
Tesis Doctoral
Canales iónicos de neuronas septales aisladas: Caracterización electrofisiológica y modulación por TRH y LHRH
(1989)
El presente trabajo continua con una de las líneas de investigación de nuestro grupo que trata del estudio de las propiedades ... |
Tesis Doctoral
Adaptación morfofuncional renal tras nefrectomía unilateral en el adulto
(1989)
En el presente estudio se analizaron los cambios morfológicos y funcionales del riñón remanente tras la nefrectomía de ... |
Artículo
Properties of Calcium and Potassium Currents of Clonal Adrenocortical Cells
(1989)
The ionic currents of clonal Y-1 adrenocortical cells were studied using the whole-cell variant of the patch-clamp technique. ... |
Artículo
Ionic currents in dispersed chemoreceptor cells of the mammalian carotid body
(1989)
Ionic currents of enzymatically dispersed type I and type II cells of the carotid body have been studied using the whole ... |
Artículo
Low pO2 selectively inhibits K channel activity in chemoreceptor cells of the mammalian carotid body
(1989)
The hypothesis that changes in environmental O2 tension (pO2) could affect the ionic conductances of dissociated type I ... |
Tesis Doctoral
Repercusión de las alteraciones en la función respiratoria sobre el síndrome de apnea del sueño
(1988)
El síndrome de apnea del sueño (SAS), provoca episodios de desaturación nocturna que a la larga provoca hipertensión ... |
| Tesis Doctoral |
Tesis Doctoral
Sistema para la adquisición, almacenamiento y análisis de corrientes iónicas transmembrana
(1987)
El objetivo general del presente trabajo ha sido el diseño e implementación de un sistema automatizado para el control del ... |
Artículo
Effects of membrane depolarization and divalent-cations on anaphylactic histamine secretion
(1986)
The effects of membrane depolariz.ation and divalent cations on histamine release have been studied in sensitized mast ... |
Tesis Doctoral
Electrofisiología de células adrenocorticales: Estudio mediante el registro intracelular y la técnica de “patch clamp”
(1985)
El presente trabajo se centra en el estudio de las características electrofisiológicas de células adrenocorticales en ... |
Artículo
Depolarizing response of rat parathyroid cells to divalent cations
(1983)
Membrane potentials were recorded from rat parathyroid glands continuously perfused in vitro. At 1 .5 mM external Ca", the ... |
Artículo
Currents recorded through small areas of squid axon membrane with an internal virtual ground voltage clamp
(1981)
A new voltage-clamp apparatus for the squid axon has been implemented to enable recording of currents through small areas ... |
| Tesis Doctoral |