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Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways

 

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Opened Access Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways
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Author: Klein, Hannah L.
Bačinskaja, Giedré
Che, Jun
Cheblal, Anais
Elango, Rajula
Epshtein, Anastasiya
Fitzgerald, Devon M.
Gómez González, Belén
Khan, Sharik R.
Kumar, Sandeep Mothish
Leland, Bryan A.
Marie, Léa
Aguilera López, Andrés
Department: Universidad de Sevilla. Departamento de Genética
Date: 2019
Published in: Microbial Cell, 6 (1), 1-64.
Document type: Article
Abstract: Understanding the plasticity of genomes has been greatly aided by assays for recombination, repair and mutagenesis. These assays have been developed in microbial systems that provide the advantages of genetic and molecular reporters that can readily be manipulated. Cellular assays comprise genetic, molecular, and cytological reporters. The assays are powerful tools but each comes with its particular advantages and limitations. Here the most commonly used assays are reviewed, discussed, and presented as the guidelines for future studies.
Cite: Klein, H.L., Bačinskaja, G., Che, J., Cheblal, A., Elango, R., Epshtein, A.,...,Aguilera López, A. (2019). Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways. Microbial Cell, 6 (1), 1-64.
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URI: https://hdl.handle.net/11441/86449

DOI: 10.15698/mic2019.01.664

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