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Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways

 

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Opened Access Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways
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Author: Gómez González, Belén
Klein, Hannah L.
Chebal, Anais
Che, Jun
Bačinskaja, Giedrė
Department: Universidad de Sevilla. Departamento de Genética
Date: 2019
Published in: Microbial Cell, 6 (1), 1-64.
Document type: Article
Abstract: Understanding the plasticity of genomes has been greatly aided by assays for recombination, repair and mutagenesis. These assays have been developed in microbial systems that provide the advantages of genetic and molecular reporters that can readily be manipulated. Cellular assays comprise genetic, molecular, and cytological reporters. The assays are powerful tools but each comes with its particular advantages and limitations. Here the most commonly used assays are reviewed, discussed, and presented as the guidelines for future studies.
Cite: Gómez González, B., Klein, H.L., Chebal, A., Che, J. y Bačinskaja, G. (2019). Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways. Microbial Cell, 6 (1), 1-64.
Size: 3.530Mb
Format: PDF

URI: https://hdl.handle.net/11441/85678

DOI: 10.15698/mic2019.01.664

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This work is under a Creative Commons License: 
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