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Intracellular proton pumps as targets in chemotherapy: V-ATPases and cancer

 

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Opened Access Intracellular proton pumps as targets in chemotherapy: V-ATPases and cancer
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Author: Hernández López, Agustín
Serrano Bueno, Gloria
Pérez Castiñeira, José Román
Serrano Delgado, Aurelio
Department: Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular
Date: 2012
Published in: Current Pharmaceutical Design, 18 (10), 1383-1394.
Document type: Article
Abstract: Cancer cells show a metabolic shift that makes them overproduce protons; this has the potential to disturb the cellular acid-base homeostasis. However, these cells show cytoplasmic alkalinisation, increased ...
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Cite: Hernández López, A., Serrano Bueno, G., Pérez Castiñeira, J.R. y Serrano Delgado, A. (2012). Intracellular proton pumps as targets in chemotherapy: V-ATPases and cancer. Current Pharmaceutical Design, 18 (10), 1383-1394.
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URI: https://hdl.handle.net/11441/85159

DOI: 10.2174/138161212799504821

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