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Nitration of tyrosine 74 prevents human cytochrome c to play a key role in apoptosis signaling by blocking caspase-9 activation

 

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Opened Access Nitration of tyrosine 74 prevents human cytochrome c to play a key role in apoptosis signaling by blocking caspase-9 activation
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Author: García Heredia, José Manuel
Díaz Moreno, Irene
Nieto Mesa, Pedro Manuel
Orzáez, Mar
Kocanis, Stella
Teixeira, Miguel
Pérez Payá, Enrique
Díaz Quintana, Antonio Jesús
Rosa Acosta, Miguel Ángel de la
Department: Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular
Date: 2010
Published in: BBA - Bioenergetics, 1797 (6-7), 981-993.
Document type: Article
Abstract: Tyrosine nitration is one of the most common post-transcriptional modifications of proteins, so affecting their structure and function. Human cytochrome c, with five tyrosine residues, is an excellent case study as it is a well-known protein playing...
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Cite: García Heredia, J.M., Díaz Moreno, I., Nieto Mesa, P.M., Orzáez, M., Kocanis, S., Teixeira, M.,...,Rosa Acosta, M.Á.d.l. (2010). Nitration of tyrosine 74 prevents human cytochrome c to play a key role in apoptosis signaling by blocking caspase-9 activation. BBA - Bioenergetics, 1797 (6-7), 981-993.
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URI: https://hdl.handle.net/11441/84857

DOI: 10.1016/j.bbabio.2010.03.009

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