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Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson’s Disease

 

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Opened Access Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson’s Disease
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Author: García Domínguez, Irene
Veselá, Karolina
García Revilla, Juan
Carrillo Jiménez, Alejandro
Roca Ceballos, María Angustias
Santiago, Marti
Martínez de Pablos, Rocío
Venero Recio, José Luis
Department: Universidad de Sevilla. Departamento de Bioquímica y Biología Molecular
Date: 2018
Published in: Frontiers in Cellular Neuroscience, 12 (art.398), 1-16.
Document type: Article
Abstract: The impact of systemic inflammation in nigral dopaminergic cell loss remains unclear. Here, we have investigated the role of peripheral inflammation induced by systemic lipopolysaccharide (LPS) administration in the MPTP-based model of Parkinson’s d...
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Cite: García Domínguez, I., Veselá, K., García Revilla, J., Carrillo Jiménez, A., Roca Ceballos, M.A., Santiago, a.,...,Venero Recio, J.L. (2018). Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson’s Disease. Frontiers in Cellular Neuroscience, 12 (art.398), 1-16.
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URI: https://hdl.handle.net/11441/81011

DOI: 10.3389/fncel.2018.00398

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