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Divergent Effects of Metformin on an Inflammatory Model of Parkinson’s Disease

 

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Opened Access Divergent Effects of Metformin on an Inflammatory Model of Parkinson’s Disease
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Author: Tayara, Khadija
Espinosa Oliva, Ana María
García Domínguez, Irene
Ismaiel, Afrah Abdul
Boza Serrano, Antonio
Deierborg, Tomas
Martínez de Pablos, Rocío
Machado de la Quintana, Alberto
Herrera Carmona, Antonio José
Venero Recio, José Luis
Department: Universidad de Sevilla. Departamento de Bioquímica y Biología Molecular
Date: 2018
Published in: Frontiers in Cellular Neuroscience, 12 (440), 1-16.
Document type: Article
Abstract: The oral antidiabetic drug metformin is known to exhibit anti-inflammatory properties through activation of AMP kinase, thus protecting various brain tissues as cortical neurons, for example. However, the effect of metformin on the substantia nigra ...
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Cite: Tayara, K., Espinosa Oliva, A.M., García Domínguez, I., Ismaiel, A.A., Boza Serrano, A., Deierborg, T.,...,Venero Recio, J.L. (2018). Divergent Effects of Metformin on an Inflammatory Model of Parkinson’s Disease. Frontiers in Cellular Neuroscience, 12 (440), 1-16.
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Format: PDF

URI: https://hdl.handle.net/11441/80975

DOI: 10.3389/fncel.2018.00440

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