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Human mitochondrial degradosome prevents harmful mitochondrial R loops and mitochondrial genome instability

 

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Opened Access Human mitochondrial degradosome prevents harmful mitochondrial R loops and mitochondrial genome instability
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Author: Silva, Sonia
Pérez de Camino Cantos, Dolores
Aguilera López, Andrés
Department: Universidad de Sevilla. Departamento de Genética
Date: 2018
Published in: Proceedings of the National Academy of Science, 115 (43), 11024-11029.
Document type: Article
Abstract: R loops are nucleic acid structures comprising an DNA-RNA hybrid and a displaced single-stranded DNA. These structures may occur transiently during transcription, playing essential biological functions. However, persistent R loops may become patholo...
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Cite: Silva, S., Pérez de Camino Cantos, D. y Aguilera López, A. (2018). Human mitochondrial degradosome prevents harmful mitochondrial R loops and mitochondrial genome instability. Proceedings of the National Academy of Science, 115 (43), 11024-11029.
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URI: https://hdl.handle.net/11441/80447

DOI: 10.1073/pnas.1807258115

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