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dc.creatorDomínguez-Trujillo, Cristinaes
dc.creatorGarvi Higueras, María Doloreses
dc.creatorSalazar-Moya, Albaes
dc.creatorLebrato Martínez, Juliánes
dc.creatorRodríguez-Ortiz, José Antonioes
dc.creatorLebrato Vázquez, Claraes
dc.creatorTorres Hernández, Yadires
dc.creatorBeltrán, A.M.es
dc.date.accessioned2018-11-13T20:06:16Z
dc.date.available2018-11-13T20:06:16Z
dc.date.issued2019
dc.identifier.citationDomínguez Trujillo, C., Garvi Higueras, M.D., Salazar-Moya, A., Lebrato Martínez, J., Rodríguez-Ortiz, J.A., Lebrato Vázquez, C.,...,Beltrán Custodio, A.M. (2019). Bacterial behavior on coated porous titanium substrates for biomedical applications. Surface and Coatings Technology, 357, 896-902.
dc.identifier.issn0257-8972es
dc.identifier.urihttps://hdl.handle.net/11441/80132
dc.description.abstractIn this work, bacterial behavior on dense and porous titanium substrates is discussed. Porous titanium was fabricated by a space holder technique (using 50 vol%, NH4HCO3 with particle sizes between 250 and 355 μm). These substrates were coated by sulfonated PEEK (termed SPEEK). Characterization of the porous substrate was carried out using the Archimedes Method, Image Analysis, and three-dimensional X-ray Micro-Computed Tomography (including total and interconnected porosity, equivalent diameter, and pore shape factor), as well as mechanical characterization (specifically stiffness and yield strength). A detailed study was performed here to investigate the influence of substrate porosity on the adhesion and proliferation of E. coli, MRSA, and P. aeruginosa (common causes of orthopedic device-associated infections). Bacterial colonization was examined in terms of the initial bacterial concentration, as well as bacterial adherence to and growth on the surface and inside the pores. Results suggest that fully dense titanium supported the least bacterial colonization, while the porous titanium promoted bacterial growth in the medium and inside the cavities. Furthermore, the SPEEK coating deposited onto the samples inhibited bacteria growth inside the porous materials. In this manner, this study showed for the first time that SPEEK could have potential antibacterial properties to offset the increase in bacteria growth commonly observed in porous materials.es
dc.description.sponsorshipJunta de Andalucía-FEDER (Spain) Ref. P12-TEP-1401es
dc.description.sponsorshipMinistry of Economy and Competitiveness of Spain, MAT2015-71284-Pes
dc.formatapplication/pdfes
dc.language.isoenges
dc.publisherElsevieres
dc.relation.ispartofSurface and Coatings Technology, 357, 896-902.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectPorous titaniumes
dc.subjectStress shieldinges
dc.subjectBacterial behaviores
dc.subjectNovel sulfonated PEEKes
dc.titleBacterial behavior on coated porous titanium substrates for biomedical applicationses
dc.typeinfo:eu-repo/semantics/articlees
dc.type.versioninfo:eu-repo/semantics/acceptedVersiones
dc.rights.accessrightsinfo:eu-repo/semantics/embargoAccesses
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Ingeniería y Ciencia de los Materiales y del Transportees
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Ingeniería Química y Ambientales
dc.relation.projectIDP12-TEP-1401es
dc.relation.projectIDMAT2015-71284-Pes
dc.date.embargoEndDate2021-02-01
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S0257897218312052es
dc.identifier.doi10.1016/j.surfcoat.2018.10.098es
dc.contributor.groupRNM159: Grupo TAR-Bioingenieríaes
dc.contributor.groupTEP123: Metalurgia e Ingeniería de los Materialeses
idus.format.extent7 p.es
idus.validador.nota24 meses de embargo según sherpa romeoes
dc.journaltitleSurface and Coatings Technologyes
dc.publication.volumen357es
dc.publication.initialPage896es
dc.publication.endPage902es
dc.contributor.funderJunta de Andalucía
dc.contributor.funderMinisterio de Economía y Competitividad (MINECO). España

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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Except where otherwise noted, this item's license is described as: Attribution-NonCommercial-NoDerivatives 4.0 Internacional