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RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation

 

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Opened Access RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation
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Author: Buchrieser, Julian
Oliva Martín, María José
Moore, Michael D.
Long, Joshua C. D.
Cowley, Sally A.
Long, Joshua C. D.
Pérez Simón, José Antonio
Venero Recio, José Luis
Department: Universidad de Sevilla. Departamento de Bioquímica y Biología Molecular
Date: 2018
Published in: Cell Death and Disease, 9 (10), 1-13.
Document type: Article
Abstract: In this study, we took advantage of human-induced pluripotent stem cells (hiPSC) and CRISPR/Cas9 technology to investigate the potential roles of RIPK1 in regulating hematopoiesis and macrophage differentiation, proinflammatory activation, and cell ...
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Cite: Buchrieser, J., Oliva Martín, M.J., Moore, M.D., Long, J.C.D., Cowley, S.A., Long, J.C.D.,...,Venero Recio, J.L. (2018). RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation. Cell Death and Disease, 9 (10), 1-13.
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URI: https://hdl.handle.net/11441/79212

DOI: 10.1038/s41419-018-1053-4

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