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A Carotenogenic Enzyme Aggregate in Phycomyces: Evidence from Quantitive Complementation

 

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Opened Access A Carotenogenic Enzyme Aggregate in Phycomyces: Evidence from Quantitive Complementation
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Author: Guardia, M.D. de la
González Aragón, Carlos
Murillo, F. Javier
Cerdá Olmedo, Enrique
Department: Universidad de Sevilla. Departamento de Genética
Date: 1971
Published in: Proceedings of the National Academy of Sciences, 68 (9), 2012-2015.
Document type: Article
Abstract: Wild-type Phycomyces blakesleeanus accumulates β-carotene, while the mutant strain C2 is unable to synthesize carotenoids, and the mutant strain C9 accumulates lycopene. Heterokaryons containing a proportion, p, of C2 nuclei and (l — p) of C9 nuclei accumulate lycopene, γ-carotene, and β-carotene in the relative amounts (l — p), p(l — p), and p2, respectively, for different values of p. It is shown that these results are expected from the operation of a carotenogenic enzyme aggregate that works as an assembly line and contains two copies of a cyclase, which is defective in strain C9, as well as other enzymes.
Cite: Guardia, M.D.d.l., González Aragón, C., Murillo, F.J. y Cerdá Olmedo, E. (1971). A Carotenogenic Enzyme Aggregate in Phycomyces: Evidence from Quantitive Complementation. Proceedings of the National Academy of Sciences, 68 (9), 2012-2015.
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URI: https://hdl.handle.net/11441/79039

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